Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Matthew Tippin"'
Autor:
Liankun Song, Merci Mino, Jana Yamak, Vyvyan Nguyen, Derron Lopez, Victor Pham, Ali Fazelpour, Vinh Le, Dongjun Fu, Matthew Tippin, Edward Uchio, Xiaolin Zi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
We have previously demonstrated the in vivo chemopreventive efficacy of flavokawain A (FKA), a novel chalcone from the kava plant, in prostate carcinogenesis models. However, the mechanisms of the anticarcinogenic effects of FKA remain largely unknow
Externí odkaz:
https://doaj.org/article/967770aa20404a1397ca52cd525ede26
Autor:
Xuesen Li, Victor Pham, Matthew Tippin, Dongjun Fu, Raymond Rendon, Liankun Song, Edward Uchio, Bang H. Hoang, Xiaolin Zi
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Flavokawain B (FKB) has been identified from kava root extracts as a potent apoptosis inducer for inhibiting the growth of various cancer cell lines, including prostate cancer. However, the molecular targets of FKB in prostate can
Externí odkaz:
https://doaj.org/article/eb097e67226a4574a6e3d78c315113a9
Autor:
Liankun Song, Vyvyan Nguyen, Jun Xie, Matthew Tippin, Le TP Truong, Christopher A. Blair, Beverly Wang, Edward Uchio, Xiaolin Zi
Publikováno v:
Cancer Research. 83:1687-1687
Docetaxel has been the standard first-line chemotherapy for lethal metastatic prostate cancer (mPCa) since 2004, but the resistance to docetaxel treatment is common. The molecular mechanisms of docetaxel resistance remain largely unknown and could be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fae357525c5a7268d860560c0b94650
https://doi.org/10.1158/1538-7445.am2023-1687
https://doi.org/10.1158/1538-7445.am2023-1687
Autor:
Matthew Tippin, Xuesen Li, Xiaolin Zi, Jun Xie, Shuan Meng, Edward Uchio, Liankun Song, Shan Xu
Publikováno v:
Journal of translational genetics and genomics
Aim Here, we aim to evaluate the chemopreventive efficacy of kava root extracts (KRE) in transgenic adenocarcinoma of the mouse prostate (TRAMP) mice and investigate potential molecular targets of kavalactones, the main components of kava. Methods TR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0c3371e842f980d509da29078416cc
https://pubmed.ncbi.nlm.nih.gov/34368644
https://pubmed.ncbi.nlm.nih.gov/34368644
Autor:
Thanh H Le, Vinh X Le, Raymond Rendon, Victor Pham, Xiaolin Zi, Jose Cedano, Dong-Jun Fu, Matthew Tippin, Marvin Miller, Ericka Agredano
Publikováno v:
Molecular carcinogenesis, vol 59, iss 2
Mol Carcinog
Mol Carcinog
Gartanin, a 4-prenylated xanthone, has been identified from the purple mangosteen fruit as a potent growth inhibitor of various cancer cell lines, including prostate cancer. However, much of Gartanin’s anti-cancer mechanism remains unknown. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cd89a7a8fa5d5c522bfd7dc41a9ca4
https://doi.org/10.1002/mc.23140
https://doi.org/10.1002/mc.23140
Autor:
Liankun Song, Vyvyan Nguyen, Shan Xu, Jana Yamak, Kia Arabzadehkaffash, Ali Fazelpour, Merci Mino, Matthew Tippin, Shuang Meng, Xiaolin Zi
Publikováno v:
Cancer Research. 82:1-1
S-phase kinase associated protein 2 (Skp2) is a promising drug target as studies have demonstrated that Skp2 is required for spontaneous tumor development that occurs in the retinoblastoma protein (pRb), Pten, or p53 deficient mice. We, therefore, ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a401c37187883676ad563d3db0b0d6
https://doi.org/10.1158/1538-7445.am2022-1
https://doi.org/10.1158/1538-7445.am2022-1
Autor:
Liankun Song, Merci Mino, Jana Yamak, Vyvyan Nguyen, Derron Lopez, Victor Pham, Ali Fazelpour, Vinh Le, Dongjun Fu, Matthew Tippin, Xiaolin Zi
Publikováno v:
Cancer Research. 82:2-2
Prostate cancer stem cells (PCSC) are small tumor subpopulations capable of self-renewal and driving prostate cancer heterogeneity, which is critical for cancer initiation, recurrence, and development of therapeutic resistance. Thus, there’s an urg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d14d5e752dec7073d09e06c5537d0be
https://doi.org/10.1158/1538-7445.am2022-2
https://doi.org/10.1158/1538-7445.am2022-2
Autor:
Liankun Song, Jia-Jia Yang, Sheng-Nan Huang, Yu-Hui Hou, Ping Li, Victor Pham, Li-Rong Zhang, Dong-Jun Fu, Xiaolin Zi, Wei-Li Xue, Sai-Yang Zhang, Matthew Tippin
Publikováno v:
European Journal of Medicinal Chemistry. 157:50-61
Novel bioactive heterocycles containing a 3,4,5-trimethoxyphenyl fragment as antiproliferative agents by targeting tubulin were synthesized and their preliminary structure activity relationships (SARs) were explored. Among all these chemical agents,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee859e6f93dc9eaa7b92ba41054c3cb3
https://doi.org/10.1016/j.ejmech.2018.07.060
https://doi.org/10.1016/j.ejmech.2018.07.060
Autor:
Kia Arabzadehkaffash, Ali Fazelpour, Matthew Tippin, Dongjun Fu, Liankun Song, Shan Xu, Xiaolin Zi
Publikováno v:
Cancer Research. 80:1146-1146
S-phase kinase associated protein 2 (Skp2) is a promising drug target as studies have demonstrated that Skp2 is required for spontaneous tumor development that occurs in the retinoblastoma protein (pRb), Pten or p53 deficient mice. We therefore have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e99a1afb4d21036fba89fc01ef2df8d
https://doi.org/10.1158/1538-7445.am2020-1146
https://doi.org/10.1158/1538-7445.am2020-1146
Autor:
Dong-Jun Fu, Matthew Tippin, Xuesen Li, Victor Pham, Bang H. Hoang, Shan Xu, Liankun Song, Xiaolin Zi
Publikováno v:
Cancer Research. 78:275-275
Flavokawain B, a chalcone isolated from kava root extracts, has been shown to inhibit the in vitro and in vivo growth of various cancer cell lines via induction of apoptosis. However, the mechanism of flavokawain B's action remains largely unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a699b38c2337139da8833e1c93ab451
https://doi.org/10.1158/1538-7445.am2018-275
https://doi.org/10.1158/1538-7445.am2018-275