Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Matthew Taliaferro"'
Autor:
Jason Hartwig, J. N. Chung, Jun Dong, Bo Han, Hao Wang, Samuel Darr, Matthew Taliaferro, Shreykumar Jain, Michael Doherty
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract The enabling of in-space cryogenic engines and cryogenic fuel depots for future manned and robotic space exploration missions begins with technology development of advanced cryogenic fluid management systems upstream in the propellant feed s
Externí odkaz:
https://doaj.org/article/3cb7648c9e734dd488ad4bb68f073af5
Autor:
Seungjae Lee, Yen-Chung Chen, FCA Consortium, Austin E. Gillen, J. Matthew Taliaferro, Bart Deplancke, Hongjie Li, Eric C. Lai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Single cell data provides cellular resolution on gene expression, but is rarely mined for isoforms. Analysis of 3' isoforms across ~250 Drosophila cell types reveals the cellular bases for numerous tissue-specific 3' programs, identifies new 3' progr
Externí odkaz:
https://doaj.org/article/819428a6b3ea4eb7910be5712585850b
Publikováno v:
eLife, Vol 12 (2023)
RNA molecules are localized to specific subcellular regions through interactions between RNA regulatory elements and RNA binding proteins (RBPs). Generally, our knowledge of the mechanistic details behind the localization of a given RNA is restricted
Externí odkaz:
https://doaj.org/article/4e25877ba12a40c7921efb1d428d0bdf
Autor:
Raeann Goering, Krysta L. Engel, Austin E. Gillen, Nova Fong, David L. Bentley, J. Matthew Taliaferro
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background The sequence content of the 3′ UTRs of many mRNA transcripts is regulated through alternative polyadenylation (APA). The study of this process using RNAseq data, though, has been historically challenging. Results To combat this
Externí odkaz:
https://doaj.org/article/139d0500d48949fbb75060e908f3fdf8
Autor:
Ankita Arora, Raeann Goering, Hei Yong G. Lo, Joelle Lo, Charlie Moffatt, J. Matthew Taliaferro
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Alternative polyadenylation (APA) is a widespread and conserved regulatory mechanism that generates diverse 3′ ends on mRNA. APA patterns are often tissue specific and play an important role in cellular processes such as cell proliferation, differe
Externí odkaz:
https://doaj.org/article/d58aeafb1eb14adcaa32231bba74675a
Autor:
Nisha Raj, Zachary T. McEachin, William Harousseau, Ying Zhou, Feiran Zhang, Megan E. Merritt-Garza, J. Matthew Taliaferro, Magdalena Kalinowska, Samuele G. Marro, Chadwick M. Hales, Elizabeth Berry-Kravis, Marisol W. Wolf-Ochoa, Veronica Martinez-Cerdeño, Marius Wernig, Lu Chen, Eric Klann, Stephen T. Warren, Peng Jin, Zhexing Wen, Gary J. Bassell
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108991- (2021)
Summary: Transcriptional silencing of the FMR1 gene in fragile X syndrome (FXS) leads to the loss of the RNA-binding protein FMRP. In addition to regulating mRNA translation and protein synthesis, emerging evidence suggests that FMRP acts to coordina
Externí odkaz:
https://doaj.org/article/76c647a47e0f490d9394ecbde774aa77
Autor:
Seungjae Lee, Lu Wei, Binglong Zhang, Raeann Goering, Sonali Majumdar, Jiayu Wen, J Matthew Taliaferro, Eric C Lai
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009439 (2021)
ELAV/Hu factors are conserved RNA binding proteins (RBPs) that play diverse roles in mRNA processing and regulation. The founding member, Drosophila Elav, was recognized as a vital neural factor 35 years ago. Nevertheless, little was known about its
Externí odkaz:
https://doaj.org/article/ad2a20e13969435ebb449e246176d61a
Autor:
Sara Espinosa, Francesca De Bortoli, Xueni Li, John Rossi, Marisa E. Wagley, Hei-Yong G. Lo, J. Matthew Taliaferro, Rui Zhao
Publikováno v:
RNA. 29:97-110
Human PRPF39 is a homolog of the yeast Prp39 and Prp42 paralogs. We have previously shown that human PRPF39 forms a homodimer that interacts with the CTD of U1C, mirroring the yeast Prp39/Prp42 heterodimer. We demonstrate here that PRPF39 knockdown i
Autor:
Ankita Arora, Roberto Castro-Gutierrez, Charlie Moffatt, Davide Eletto, Raquel Becker, Maya Brown, Andreas E Moor, Holger A Russ, J Matthew Taliaferro
Publikováno v:
Nucleic Acids Research. 50:10626-10642
Hundreds of RNAs are enriched in the projections of neuronal cells. For the vast majority of them, though, the sequence elements that regulate their localization are unknown. To identify RNA elements capable of directing transcripts to neurites, we d
Autor:
Chun Hao Wong, Steven W. Wingett, Chen Qian, J. Matthew Taliaferro, Douglas Ross-Thriepland, Simon L. Bullock
The cytoplasmic dynein-1 (dynein) motor plays a key role in cellular organisation by transporting a wide variety of cellular constituents towards the minus ends of microtubules. However, relatively little is known about how the biosynthesis, assembly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21355d6db357473e56d262f912da4507
https://doi.org/10.1101/2023.03.01.530592
https://doi.org/10.1101/2023.03.01.530592