Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Matthew T. Goulet"'
Autor:
Matthew Hitron, Michael D. Karol, Marjie L. Hard, Xiaoshu Dai, Colleen F. Mclaughlin, Scott J. Brantley, Matthew T. Goulet
Publikováno v:
Clinical Pharmacology in Drug Development
Napabucasin is an orally administered reactive oxygen species generator that is bioactivated by the intracellular antioxidant nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase 1. Napabucasin induces cell death in cancer cells, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd249a6a220f2dc5c28a0e4212bd82e9
http://europepmc.org/articles/PMC8453567
http://europepmc.org/articles/PMC8453567
Autor:
Michael D. Karol, Marjie L. Hard, Scott J. Brantley, Xiaoshu Dai, Matthew T. Goulet, Colleen F. Mclaughlin, Matthew Hitron
Publikováno v:
Journal of Clinical Oncology. 38:142-142
142 Background: Napabucasin is an NQO1-bioactivatable investigational agent hypothesized to affect multiple oncogenic cellular pathways including pSTAT3 through the generation of reactive oxygen species. This phase 1 open-label study evaluated the DD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fba3583533ad2021968f62cf1ae4f80
https://doi.org/10.1200/jco.2020.38.4_suppl.142
https://doi.org/10.1200/jco.2020.38.4_suppl.142
Autor:
Sunghee Park, Suzanne E. Wardell, Matthew T. Goulet, John R. Guyton, Erik R. Nelson, Ching-Yi Chang, Donald P. McDonnell, J. Jasper, John D. Norris
Publikováno v:
Cancer Research. 74:4976-4982
Obesity and altered lipid metabolism are risk factors for breast cancer in pre- and post-menopausal women. These pathologic relationships have been attributed in part to the impact of cholesterol on the biophysical properties of cell membranes and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654fdaaf9ec7a41929d4b9eb3a04157b
https://doi.org/10.1158/0008-5472.can-14-1756
https://doi.org/10.1158/0008-5472.can-14-1756
Autor:
Zachary Sexton, Brett J. Pellock, Matthew T Goulet, Taylor Mezoian, Nicholas Q. Mazzucca, Katherine E Douglas, Jessica M Osborn, Meghan Keane, Christopher M. Brennan, Taylor M. Hunt
Publikováno v:
BMC Microbiology
BMC Microbiology, Vol 13, Iss 1, p 33 (2013)
BMC Microbiology, Vol 13, Iss 1, p 33 (2013)
Background Hfq is an RNA chaperone protein that has been broadly implicated in sRNA function in bacteria. Here we describe the construction and characterization of a null allele of the gene that encodes the RNA chaperone Hfq in Shewanella oneidensis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07db862aa0fd3887737775533db2a727
https://pubmed.ncbi.nlm.nih.gov/23394078
https://pubmed.ncbi.nlm.nih.gov/23394078
Autor:
Matthew T Goulet, Brian Tjaden, Christopher M. Brennan, Karl Hoegler, Brett J. Pellock, Zachary Sexton, Christine D'Agostino, Meaghan Keane
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844a88931ae51203ad0d60394e129b61
https://doi.org/10.1096/fasebj.26.1_supplement.952.2
https://doi.org/10.1096/fasebj.26.1_supplement.952.2