Zobrazeno 1 - 10
of 402
pro vyhledávání: '"Matthew T Weirauch"'
Autor:
Chengyi Sun, Casey O. Swoboda, Fabian Montecino Morales, Cristofer Calvo, Michael J. Petrany, Sreeja Parameswaran, Andrew VonHandorf, Matthew T. Weirauch, Christoph Lepper, Douglas P. Millay
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Multinucleated skeletal muscle cells need to acquire additional nuclei through fusion with activated skeletal muscle stem cells when responding to both developmental and adaptive growth stimuli. A fundamental question in skeletal muscle biol
Externí odkaz:
https://doaj.org/article/8c56113a1c204bb3a256923ff6709e46
Autor:
Qiang Wang, Taehyeung Kim, Marta Martínez-Bonet, Vitor R. C. Aguiar, Sangwan Sim, Jing Cui, Jeffrey A. Sparks, Xiaoting Chen, Marc Todd, Brian Wauford, Miranda C. Marion, Carl D. Langefeld, Matthew T. Weirauch, Maria Gutierrez-Arcelus, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utiliz
Externí odkaz:
https://doaj.org/article/1e3df32c4843408cb3495d4e0d4bcf9e
Autor:
Kenyatta C. M. F. Viel, Sreeja Parameswaran, Omer A. Donmez, Carmy R. Forney, Matthew R. Hass, Cailing Yin, Sydney H. Jones, Hayley K. Prosser, Arame A. Diouf, Olivia E. Gittens, Lee E. Edsall, Xiaoting Chen, Hope Rowden, Katelyn A. Dunn, Rui Guo, Andrew VonHandorf, Merrin Man Long Leong, Kevin Ernst, Kenneth M. Kaufman, Lucinda P. Lawson, Ben Gewurz, Bo Zhao, Leah C. Kottyan, Matthew T. Weirauch
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background There are two major genetic types of Epstein-Barr Virus (EBV): type 1 (EBV-1) and type 2 (EBV-2). EBV functions by manipulating gene expression in host B cells, using virus-encoded gene regulatory proteins including Epstein-Barr N
Externí odkaz:
https://doaj.org/article/155fc47c06e74fd5b11dee66241b344d
Autor:
Taehyeung Kim, Marta Martínez-Bonet, Qiang Wang, Nicolaj Hackert, Jeffrey A. Sparks, Yuriy Baglaenko, Byunghee Koh, Roxane Darbousset, Raquel Laza-Briviesca, Xiaoting Chen, Vitor R. C. Aguiar, Darren J. Chiu, Harm-Jan Westra, Maria Gutierrez-Arcelus, Matthew T. Weirauch, Soumya Raychaudhuri, Deepak A. Rao, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Fine-mapping and functional studies implicate rs117701653, a non-coding single nucleotide polymorphism in the CD28/CTLA4/ICOS locus, as a risk variant for rheumatoid arthritis and type 1 diabetes. Here, using DNA pulldown, mass spectrometry,
Externí odkaz:
https://doaj.org/article/89591f74d78449f789de95d34d7df2b8
Autor:
John B Harley, Viktoryia Laurynenka, Sreeja Parameswaran, Xiaoting Chen, Leah C Kottyan, Matthew T Weirauch, Kenneth M Kaufman, Iouri Chepelev
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/78b17783b62447819ce41c9c2d6c3904
Autor:
Li Wang, Robert M. Rossi, Xiaoting Chen, Jing Chen, Jilian Runyon, Mehak Chawla, Daniel Miller, Carmy Forney, Arthur Lynch, Xuzhe Zhang, Fansheng Kong, Bo Jacobsson, Leah C. Kottyan, Matthew T. Weirauch, Ge Zhang, Louis J. Muglia
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Preterm birth (PTB), defined as delivery before 37 gestational weeks, imposes significant public health burdens. A recent maternal genome-wide association study of spontaneous PTB identified a noncoding locus near the angiotensin
Externí odkaz:
https://doaj.org/article/be5cdb1ceca847a8807404f5cbf105e9
Autor:
Mary C. Bedard, Tafadzwa Chihanga, Adrean Carlile, Robert Jackson, Marion G. Brusadelli, Denis Lee, Andrew VonHandorf, Mark Rochman, Phillip J. Dexheimer, Jeffrey Chalmers, Gerard Nuovo, Maria Lehn, David E. J. Williams, Aditi Kulkarni, Molly Carey, Amanda Jackson, Caroline Billingsley, Alice Tang, Chad Zender, Yash Patil, Trisha M. Wise-Draper, Thomas J. Herzog, Robert L. Ferris, Ady Kendler, Bruce J. Aronow, Matthew Kofron, Marc E. Rothenberg, Matthew T. Weirauch, Koenraad Van Doorslaer, Kathryn A. Wikenheiser-Brokamp, Paul F. Lambert, Mike Adam, S. Steven Potter, Susanne I. Wells
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The role of keratinocyte subpopulations in the different phases of the viral cycle during HPV16 infection remains to be characterised. Here, single cell RNA sequencing of HPV16 infected and uninfected organoids identifies 12 distinct keratinocyte pop
Externí odkaz:
https://doaj.org/article/944133d8df914bc3ab573aab9d9f4d14
Autor:
Chong Wang, Xiang Liu, Jun Liang, Yohei Narita, Weiyue Ding, Difei Li, Luyao Zhang, Hongbo Wang, Merrin Man Long Leong, Isabella Hou, Catherine Gerdt, Chang Jiang, Qian Zhong, Zhonghui Tang, Carmy Forney, Leah Kottyan, Matthew T. Weirauch, Benjamin E. Gewurz, Mu-sheng Zeng, Sizun Jiang, Mingxiang Teng, Bo Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The dynamic and temporal changes of host genome architecture during Epstein-Barr virus (EBV) transformation are not well known. Here the authors transform human primary B lymphocyte into lymphoblastoid cell lines (LCLs) with EBV and show that the hos
Externí odkaz:
https://doaj.org/article/59cb7a98e57741bda7d5d423987fef6d
Autor:
Hailu Fu, Haizi Zheng, Xiaoting Chen, Matthew T. Weirauch, Louis J. Muglia, Li Wang, Yaping Liu
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Cis-regulatory elements are coordinated to regulate the expression of their targeted genes. However, the joint measurement of cis-regulatory elements’ activities and their interactions in spatial proximity is limited by the current sequenc
Externí odkaz:
https://doaj.org/article/52b3c226b97f4a43a7f7a6d0e0f0cf5f
Autor:
Ruhi Gulati, Michael Johnston, Maria Rivas, Ashley Cast, Meenasri Kumbaji, Margaret A. Hanlon, Sanghoon Lee, Ping Zhou, Charissa Lake, Emily Schepers, Kyung‐Won Min, Je‐Hyun Yoon, Rebekah Karns, Lola M. Reid, Dolores Lopez‐Terrada, Lubov Timchenko, Sreeja Parameswaran, Matthew T. Weirauch, Sarangarajan Ranganathan, Alexander Bondoc, James Geller, Gregory Tiao, Soona Shin, Nikolai Timchenko
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2950-2963 (2022)
Abstract Fibrolamellar hepatocellular carcinoma (FLC) is a disease that occurs in children and young adults. The development of FLC is associated with creation of a fusion oncoprotein DNAJB1‐PKAc kinase, which activates multiple cancer‐associated
Externí odkaz:
https://doaj.org/article/3b39dff74afb4b70b221609038dea359