Zobrazeno 1 - 10
of 374
pro vyhledávání: '"Matthew T V Chan"'
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250777 (2021)
IntroductionIn adults with cardiovascular risk factors undergoing major noncardiac surgery, unrecognized obstructive sleep apnea (OSA) was associated with postoperative cardiovascular complications. There is a need for an easy and accessible home dev
Externí odkaz:
https://doaj.org/article/12106a7b8ba34731a6f25a566765c326
Autor:
Wenye Xu, Yuchen Zhang, Dongjiao Chen, Dan Huang, Yang Zhao, Wei Hu, Ling Lin, Yingzhi Liu, Shilan Wang, Judeng Zeng, Chuan Xie, Hung Chan, Qing Li, Huarong Chen, Xiaodong Liu, Sunny H. Wong, Jun Yu, Francis K. L. Chan, Matthew T. V. Chan, Siew C. Ng, William K. K. Wu, Lin Zhang
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Fusobacterium nucleatum (F. nucleatum) is one of the key tumorigenic bacteria in colorectal cancer (CRC), yet how F. nucleatum is involved in colorectal cancer carcinogenesis remains unknown. Results In the present study, we carri
Externí odkaz:
https://doaj.org/article/b61bd6e59fff42d584fb0a93eec26fe1
Autor:
Judeng Zeng, Chuan Xie, Ziheng Huang, Chi H. Cho, Hung Chan, Qing Li, Hassan Ashktorab, Duane T. Smoot, Sunny H. Wong, Jun Yu, Wei Gong, Cong Liang, Hongzhi Xu, Huarong Chen, Xiaodong Liu, Justin C. Y. Wu, Margaret Ip, Tony Gin, Lin Zhang, Matthew T. V. Chan, Wei Hu, William K. K. Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The role of N6-methyladenosine (m6A) modification of host mRNA during bacterial infection is unclear. Here, we show that Helicobacter pylori infection upregulates host m6A methylases and increases m6A levels in gastric epithelial cells. Redu
Externí odkaz:
https://doaj.org/article/faf3d02f8eca48d192ffb1a37c4210da
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75804 (2013)
BACKGROUND: Signal transducer and activator of transcription 3 (Stat3) is known to induce cell proliferation and inflammation by regulating gene transcription. Recent studies showed that Stat3 modulates nociceptive transmission by reducing spinal ast
Externí odkaz:
https://doaj.org/article/20a7de4b84f944198f7dfed1606b7797
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50845 (2012)
ObjectivesWe compared the expelled air dispersion distances during coughing from a human patient simulator (HPS) lying at 45° with and without wearing a surgical mask or N95 mask in a negative pressure isolation room.MethodsAirflow was marked with i
Externí odkaz:
https://doaj.org/article/64ee3c8419fe4d95b2c6964bcedda46d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionEmerging preclinical and clinical studies suggest that altered gut microbiome composition and functions are associated with coronavirus 2019 (COVID- 19) severity and its long-term complications. We hypothesize that COVID-19 outcome is ass
Externí odkaz:
https://doaj.org/article/38fd4c22b4c940dcb2027f6b0199e443
Autor:
Amit X. Garg, Meaghan Cuerden, Juan Cata, Matthew T. V. Chan, P. J. Devereaux, Edith Fleischmann, Ascensión Martín Grande, Barbara Kabon, Giovanni Landoni, Donna E. Maziak, Sean McLean MD, Chirag Parikh, Ekaterine Popova, Cara Reimer, Juan Carlos Trujillo Reyes, Pavel Roshanov, Daniel I. Sessler, Sadeesh Srinathan, Jessica M. Sontrop, Anna Gonzalez Tallada, Michael Ke Wang, Jennifer R. Wells, David Conen
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 10 (2023)
Background: Inflammation during and after surgery can lead to organ damage including acute kidney injury. Colchicine, an established inexpensive anti-inflammatory medication, may help to protect the organs from pro-inflammatory damage. This protocol
Externí odkaz:
https://doaj.org/article/60645a9184ac400b939f552bd0a0b3d6
Autor:
Emmanuelle Duceppe, Flavia K. Borges, David Conen, Maria Tiboni, Matthew T. V. Chan, Ameen Patel, Daniel I. Sessler, Peter A. Kavsak, Sandra Ofori, Sadeesh Srinathan, Rupert Pearse, Allan S. Jaffe, Diane Heels-Ansdell, Amit X. Garg, Shirley Pettit, Robert Sapsford, P. J. Devereaux
Publikováno v:
Anesthesiology. 138:508-522
Background The association between growth differentiation factor-15 concentrations and cardiovascular disease has been well described. The study hypothesis was that growth differentiation factor-15 may help cardiac risk stratification in noncardiac s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe7cdadf3770be7232eb9ea6a98e8fd4
https://doi.org/10.1097/aln.0000000000004539
https://doi.org/10.1097/aln.0000000000004539
Autor:
Yun Liu, Zeyao Zhu, Idy H. T. Ho, Yujian Shi, Jianzhen Li, Xia Wang, Matthew T. V. Chan, Christopher H. K. Cheng
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
MiR-430 is considered an important regulator during embryonic development, but genetic loss-of-function study is still lacking. Here we demonstrated that genetic deletion of the miR-430 cluster resulted in developmental defects in cell movement, germ
Externí odkaz:
https://doaj.org/article/fdab69c74fd8483fbb44e2c9e061dc23
Autor:
Sofie S. Pedersen, Cecilie Holse, Clara E. Mathar, Matthew T. V. Chan, Daniel I. Sessler, Yingzhi Liu, Lin Zhang, Andrea Kurz, Mike Jacka, Alexandra Torborg, Thuli Biyase, Felix R. Montes, Chew Yin Wang, Shirley Pettit, P. J. Devereaux, Christian S. Meyhoff
Publikováno v:
Anesthesia & Analgesia. 135:1021-1030
Two trials reported that a high inspiratory oxygen fraction (F io2 ) does not promote myocardial infarction or death. Observational studies can provide larger statistical strength, but associations can be due to unobserved confounding. Therefore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4cb1bacb34b8c254c13d72ca0b87f82
https://doi.org/10.1213/ane.0000000000006042
https://doi.org/10.1213/ane.0000000000006042