Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Matthew Stoner"'
Autor:
Xiulong Song, Yuan Chen, Leila Valanejad, Rajani Kaimal, Bingfang Yan, Matthew Stoner, Ruitang Deng
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3030-3044 (2013)
Expression of bile salt export pump (BSEP) is regulated by the bile acid/farnesoid X receptor (FXR) signaling pathway. Two FXR isoforms, FXRα1 and FXRα2, are predominantly expressed in human liver. We previously showed that human BSEP was isoform-d
Externí odkaz:
https://doaj.org/article/321e3c8bcb46414897464549dea7ea3e
Autor:
Nicole P Yuan, Audrey J Brooks, Molly K Burke, Robert Crocker, Gates Matthew Stoner, Paula Cook, Mei-Kuang Chen, Juan Bautista, Patricia Petralba, Shannon Whitewater, Victoria Maizes
Publikováno v:
Translational behavioral medicine. 12(6)
Underserved populations, including those from racial and ethnic groups and with low socioeconomic status, often lack access to mobile apps aimed at reducing health risk factors. This study evaluated the feasibility, acceptability, and preliminary eff
Publikováno v:
Toxicology and Applied Pharmacology. 223:28-38
The aryl hydrocarbon receptor (AhR) is expressed in estrogen receptor (ER)-positive ZR-75 breast cancer cells. Treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces CYP1A1 protein and mRNA levels and also activates inhibitory AhR-ERalpha
Autor:
Stephen Safe, Matthew Stoner, Brad Saville, Maen Abdelrahim, Chunhua Qin, Mark Wormke, Ismael Samudio
Publikováno v:
Oncogene. 23:1052-1063
Vascular endothelial growth factor (VEGF) is expressed in multiple hormone-dependent cancer cells/tumors. Treatment of ZR-75 breast cancer cells with 17beta-estradiol (E2) induced a greater than fourfold increase of VEGF mRNA levels. ZR-75 breast can
Autor:
Stephen Safe, Matthew Stoner, Jorma J. Palvimo, Mark Wormke, Olli A. Jänne, Ismael Samudio, Bradley Saville, Hetti Poukka
Publikováno v:
Journal of Biological Chemistry. 277:2485-2497
SNURF is a small RING finger protein that binds the zinc finger region of steroid hormone receptors and enhances Sp1- and androgen receptor-mediated transcription in COS and CV-1 cells. In this study, we show that SNURF coactivates both wild-type est
Autor:
Carrie A. Vyhlidal, Mark Wormke, Stephen Safe, Matthew Stoner, Dieter Marme, Fan Wang, Günter Finkenzeller, Ismael Samudio, Thu Annelise Nguyen
Publikováno v:
Journal of Biological Chemistry. 275:22769-22779
Treatment of HEC1A endometrial cancer cells with 10 nm 17beta-estradiol (E2) resulted in decreased vascular endothelial growth factor (VEGF) mRNA expression, and a similar response was observed using a construct, pVEGF1, containing a VEGF gene promot
Autor:
Stephen Safe, Robert C. Burghardt, Bradley Saville, Maen Abdelrahim, Kelcey Walker, Matthew Stoner, Mark Wormke
Publikováno v:
Molecular and cellular biology. 23(6)
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other aryl hydrocarbon receptor (AhR) ligands suppress 17beta-estradiol (E)-induced responses in the rodent uterus and mammary tumors and in human breast cancer cells. Treatment of ZR-75, T47D, and MCF-7
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 16(10)
Regulation of estrogen receptor alpha (ERalpha) plays an important role in hormone responsiveness and growth of ER-positive breast cancer cells and tumors. ZR-75 breast cancer cells were grown under conditions of normoxia (21% O(2)) or hypoxia (1% O(
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 78(1)
Structure-dependent estrogen receptor alpha (ER alpha) agonist and antagonist activities of synthetic and natural estrogenic compounds were investigated in human HepG2, MDA-MB-231 and U2 cancer cell lines. Compounds used in this study include 4'-hydr
Autor:
Fan Wang, Michael P. Kladde, Rola Barhoumi, Robert C. Burghardt, Ichen Chen, Matthew Stoner, Ismael Samudio, Carrie A. Vyhlidal, Stephen Safe
Publikováno v:
Endocrinology. 142(3)
Treatment of MCF-7 human breast cancer cells with 17beta-estradiol (E(2)) results in increased DNA synthesis and cell proliferation and enhanced enzyme activities associated with purine/pyrimidine biosynthesis. The mechanism of enhanced DNA polymeras