Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Matthew Schrag"'
Autor:
Elena Solopova, Wilber Romero-Fernandez, Hannah Harmsen, Lissa Ventura-Antunes, Emmeline Wang, Alena Shostak, Jose Maldonado, Manus J. Donahue, Daniel Schultz, Thomas M. Coyne, Andreas Charidimou, Matthew Schrag
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract We report the case of a 79-year-old woman with Alzheimer’s disease who participated in a Phase III randomized controlled trial called CLARITY-AD testing the experimental drug lecanemab. She was randomized to the placebo group and subsequen
Externí odkaz:
https://doaj.org/article/980393b02c7a4f79b9007c599dd91386
Autor:
Jay B Lusk, Lauren Wilson, Vinit Nalwade, Ailin Song, Matthew Schrag, Valerie Biousse, Fan Li, Sven Poli, Jonathan Piccini, Ying Xian, Emily O'Brien, Brian Mac Grory
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0296251 (2023)
Central retinal artery occlusion (CRAO; retinal stroke or eye stroke) is an under-recognized, disabling form of acute ischemic stroke which causes severe visual loss in one eye. The classical risk factor for CRAO is ipsilateral carotid stenosis; howe
Externí odkaz:
https://doaj.org/article/abf0173fb0d44fec95f1415ee318dd7c
Autor:
Louise Kelly, Matthew Macgregor Sharp, Isabelle Thomas, Christopher Brown, Matthew Schrag, Lissa Ventura Antunes, Elena Solopova, José Martinez-Gonzalez, Cristina Rodríguez, Roxana Octavia Carare
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100171- (2023)
Alzheimer's disease is the commonest form of dementia. It is likely that a lack of clearance of amyloid beta (Aβ) results in its accumulation in the parenchyma as Aβ oligomers and insoluble plaques, and within the walls of blood vessels as cerebral
Externí odkaz:
https://doaj.org/article/5057b191f21d46e09ea57b99f9ab1014
Autor:
Brian Mac Grory, Erez Nossek, Michael E Reznik, Matthew Schrag, Mahesh Jayaraman, Ryan McTaggart, Adam de Havenon, Shadi Yaghi, Wuwei Feng, Karen Furie, Anusha Boyanpally
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257697 (2021)
IntroductionThe carotid web is a compelling potential mechanism of embolic ischemic stroke. In this study, we aim to determine the prevalence of ipsilateral carotid web in a cohort of ischemic stroke patients and to perform a systematic review and me
Externí odkaz:
https://doaj.org/article/cf691ef6e3f54b5a88bb9b97681cd63f
Publikováno v:
MethodsX, Vol 4, Iss C, Pp 166-171 (2017)
Organotypic slicing of brain tissue from young rodents has been used as a powerful model system for biomedical research [1–3]. Organotypic slicing complements cell culture and in vivo studies in multiple facets. This system can be useful for invest
Externí odkaz:
https://doaj.org/article/425d7e575a9848d98ccae43ecb7c6046
Publikováno v:
Nutrients, Vol 10, Iss 7, p 883 (2018)
The current study highlighted several changes in measures of oxidative stress and antioxidant status that take place in the mouse brain over the course of 24 h post-mortem. Ascorbic acid (vitamin C) and glutathione both decreased significantly in cor
Externí odkaz:
https://doaj.org/article/03e660d97aef445eb09d44d90da09f51
Autor:
Deborah Rose, Annie Cavalier, Wayneho Kam, Sarah Cantrell, Jay Lusk, Matthew Schrag, Shadi Yaghi, Christoph Stretz, Adam de Havenon, Ian J. Saldanha, Teddy Y. Wu, Anna Ranta, P. Alan Barber, Elizabeth Marriott, Wayne Feng, Andrzej S. Kosinski, Daniel Laskowitz, Sven Poli, Brian Mac Grory
Publikováno v:
Stroke. 54:1192-1204
Background: Prior systematic reviews have compared the efficacy of intravenous tenecteplase and alteplase in acute ischemic stroke, assigning their relative complications as a secondary objective. The objective of the present study is to determine wh
Autor:
Jay B. Lusk, Ailin Song, Shakthi Unnithan, Hussein R. Al-Khalidi, Alen Delic, Adam de Havenon, Valérie Biousse, Matthew Schrag, Sven Poli, Jonathan P. Piccini, Ying Xian, Emily C. O’Brien, Brian Mac Grory
Publikováno v:
Stroke. 54:983-991
Background: Carotid stenosis is thought to be the primary risk factor for central retinal artery occlusion (CRAO); however, it is not known whether atrial fibrillation (AF)—a cardiac arrhythmia that underlies over 25% of cerebral ischemic strokes
Autor:
Matthew Schrag, Elena Solopova, Wilber Romero-Fernandez, Hannah Harmsen, Lissa Ventura Antunes, Emmeline Wang, Jose Maldonado, Alena Shostak, Manus Donahue, Daniel Schultz, Thomas Coyne, Andreas Charidimou
We report the case of a 79-year-old woman in good general health aside from early-stage Alzheimer’s disease who was enrolled in a randomized controlled trial of the novel therapeutic monoclonal antibody lecanemab where she was treated with the plac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532b6445263812c81d785cd311cbe41b
https://doi.org/10.1101/2023.04.26.23289061
https://doi.org/10.1101/2023.04.26.23289061
Autor:
Wilber Romero-Fernandez, Cristian Carvajal-Tapia, Alex Prusky, Ketaki Katdare, Emmeline Wang, Alena Shostak, Lissa Ventura-Antunes, Hannah Harmsen, Ethan Lippmann, Dasiel Borroto-Escuela, Jason MacGurn, Kjell Fuxe, Matthew Schrag
Examination of healthy and diseased human brain is essential to translational neuroscience. Protein-protein interactions play a pivotal role in physiological and pathological processes, but their detection is difficult, especially in aged and fixed h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad98803152ac9138e0980acce6d5118e
https://doi.org/10.21203/rs.3.rs-2570335/v1
https://doi.org/10.21203/rs.3.rs-2570335/v1