Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Matthew S. Ward"'
Publikováno v:
Clinical Ophthalmology (Auckland, N.Z.)
Matthew S Ward,1 Andrew C Hou,2 David A Murphy,2 Mason A Schmutz,3 Kamran M Riaz2 1Riverwoods Eye Center, Provo, UT, USA; 2Dean McGee Eye Institute, University of Oklahoma, Oklahoma City, OK, USA; 3Excel Eye Center, Saratoga Springs, UT, USACorrespon
Publikováno v:
Applied Microbiology and Biotechnology. 98:5551-5566
One of the challenges in antibiotic lead discovery is the difficulty and time-consuming task of determining the mechanism of action (MOA) of antibacterial compounds. In this report, we describe the development and validation of a facile and inexpensi
Autor:
Lance Roppiyakuda, Isba Silva, Divya Kanichar, Shakila Rahman, Feimeng Zhou, Jeanie M. Garcia, Ewa Kosmowska, Walfre Martinez, Jameka Jefferson, Felicia Chow, Matthew S. Ward, Michael P. Groziak, Elena Buglo, Kim P. Tran, Michelle Faust, H. Howard Xu
Publikováno v:
Bioorganicmedicinal chemistry. 24(15)
One of the hurdles in the discovery of antibiotics is the difficulty of linking antibacterial compounds to their cellular targets. Our laboratory has employed a genome-wide approach of over-expressing essential genes in order to identify cellular tar
Publikováno v:
Inorganica Chimica Acta. 343:231-243
The {Ru II (NO) + } 3+ derivatives of bleomycin-A 2 and bleomycin-B 2 have been prepared from the reaction of Ru(NO)Cl 3 (H 2 O) 2 with the commercially available Blenoxane antitumor agent. The coordination identity of the BLM donor groups in [RuNO)(
Publikováno v:
Biotechnology Progress. 17:712-719
[Pd(II)(mida)(peptide)] complexes for the series of peptides of sequence X(1)-His-X(3)-His-His were studied by molecular mechanics methods using Spartan, MMFF94, and SYBYL programs with X(1) = X(3) = glycine (G), phenylalanine (F), tyrosine (Y), tryp
Publikováno v:
Inorganica Chimica Acta. 317:290-303
trans -[Ru(NO)X(dioxocyclam)], X=Cl − and OH − , dioxocyclam=(1,4,8,11-tetraazacyclotetradecane-5,7-dione) have been prepared and characterized by NMR, IR and ESI-MS techniques. The trans -[Ru(NO)Cl(dioxocyclam)] shows the nitrosyl stretch at 184
Publikováno v:
Transition Metal Chemistry. 26:351-364
The 'caged NO' reagent, RuCl3NO(H2O)2, has been studied by n.m.r. and i.r. methods with imidazole, histidine, histamine, and N-methyliminodiacetate as complexing ligands. These ligands are representative of cellular donors that would be encountered a
Autor:
Matthew S. Ward, Rex E. Shepherd
Publikováno v:
Inorganica Chimica Acta. 311:57-68
Molecular mechanics calculations were performed using the mm 2, Spartan, mmff 94 and sybyl programs to examine the stabilities of complexes of the formulation [Pd II (mida)L 3 ] and [Pd II (mida)(hexamer peptide)] (mida 2− = N -methyliminodiacetate
Publikováno v:
Polyhedron. 19:1339-1346
The combination of [RuIII(edta)(H2O)]− (edta4−=ethylenediamine-N,N,N′N′-tetraacetate) and [FeIII(CN)6]3− in aqueous solution results in the rapid formation of [RuIII(edta)(NC)FeIII(CN)5]4− (1), which has been isolated and characterized by
Publikováno v:
Inorganica Chimica Acta. 304:60-71
[Pd(II) 2 (hdta)(H 2 O) 2 ], the Pd(II) binuclear analogue of the previously characterized [[Pt(II) 2 (hdta)Cl 2 ] 2− complex (F.-T. Lin, R.E. Shepherd, Inorg. Chim. Acta , 271 (1998) 124; R.A. Kortes, S.J. Geib, F.-T. Lin, R.E. Shepherd, Inorg. Ch