Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Matthew S. Rodeheffer"'
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112390- (2023)
Summary: White adipose tissue (WAT) distribution is sex dependent. Adipocyte hyperplasia contributes to WAT distribution in mice driven by cues in the tissue microenvironment, with females displaying hyperplasia in subcutaneous and visceral WAT, whil
Externí odkaz:
https://doaj.org/article/77bd1ad6c0034868a67813e4d7f459f3
Autor:
Rohan Varshney, Snehasis Das, G. Devon Trahan, Jacob W. Farriester, Gregory P. Mullen, Gertrude Kyere-Davies, David M. Presby, Julie A. Houck, Patricia G. Webb, Monika Dzieciatkowska, Kenneth L. Jones, Matthew S. Rodeheffer, Jacob E. Friedman, Paul S. MacLean, Michael C. Rudolph
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105750- (2023)
Summary: Establishing metabolic programming begins during fetal and postnatal development, and early-life lipid exposures play a critical role during neonatal adipogenesis. We define how neonatal consumption of a low omega-6 to −3 fatty acid ratio
Externí odkaz:
https://doaj.org/article/9bad93f7d4e444bcbb9d60d4a40fb54f
Autor:
Zachary L. Sebo, Matthew S. Rodeheffer
Publikováno v:
Molecular Metabolism, Vol 44, Iss , Pp 101141- (2021)
Objective: Low testosterone in men (hypogonadism) is associated with obesity and type II diabetes. Testosterone replacement therapy has been shown to reverse these effects. However, the mechanisms by which testosterone regulates total fat mass, fat d
Externí odkaz:
https://doaj.org/article/fa62fde5750e419dbeceaaa24af79014
Autor:
Josefine Tratwal, Rossella Labella, Nathalie Bravenboer, Greet Kerckhofs, Eleni Douni, Erica L. Scheller, Sammy Badr, Dimitrios C. Karampinos, Sarah Beck-Cormier, Biagio Palmisano, Antonella Poloni, Maria J. Moreno-Aliaga, Jackie Fretz, Matthew S. Rodeheffer, Parastoo Boroumand, Clifford J. Rosen, Mark C. Horowitz, Bram C. J. van der Eerden, Annegreet G. Veldhuis-Vlug, Olaia Naveiras
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The interest in bone marrow adiposity (BMA) has increased over the last decade due to its association with, and potential role, in a range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation, chemot
Externí odkaz:
https://doaj.org/article/929e88673c9c403abff3407ea2ce9664
Autor:
Rachel K. Zwick, Michael C. Rudolph, Brett A. Shook, Brandon Holtrup, Eve Roth, Vivian Lei, Alexandra Van Keymeulen, Victoria Seewaldt, Stephanie Kwei, John Wysolmerski, Matthew S. Rodeheffer, Valerie Horsley
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
During mammary gland involution, the organ undergoes extensive remodeling. Here, the authors explore the role of mammary gland adipose tissue (mgWAT) in this process and demonstrate that adipocyte hypertrophy and lipid trafficking underlie mgWAT expa
Externí odkaz:
https://doaj.org/article/6df449e761d24bb9b6a16a56627b5f82
Autor:
Nathan L. Price, Abhishek K. Singh, Noemi Rotllan, Leigh Goedeke, Allison Wing, Alberto Canfrán-Duque, Alberto Diaz-Ruiz, Elisa Araldi, Ángel Baldán, Joao-Paulo Camporez, Yajaira Suárez, Matthew S. Rodeheffer, Gerald I. Shulman, Rafael de Cabo, Carlos Fernández-Hernando
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2133-2145 (2018)
Summary: While therapeutic modulation of miRNAs provides a promising approach for numerous diseases, the promiscuous nature of miRNAs raises concern over detrimental off-target effects. miR-33 has emerged as a likely target for treatment of cardiovas
Externí odkaz:
https://doaj.org/article/e344e7cdc5634e7db68d175d5c1581a0
Autor:
Arthe Raajendiran, Geraldine Ooi, Jackie Bayliss, Paul E. O’Brien, Ralf B. Schittenhelm, Ashlee K. Clark, Renea A. Taylor, Matthew S. Rodeheffer, Paul R. Burton, Matthew J. Watt
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1528-1540.e7 (2019)
Summary: Adipocyte progenitor cells (APCs) provide the reservoir of regenerative cells to produce new adipocytes, although their identity in humans remains elusive. Using FACS analysis, gene expression profiling, and metabolic and proteomic analyses,
Externí odkaz:
https://doaj.org/article/20f296ab02ac4555afaf35da238c3207
Autor:
John R. Speakman, Jasper M. A. de Jong, Srishti Sinha, Klaas R. Westerterp, Yosuke Yamada, Hiroyuki Sagayama, Philip N. Ainslie, Liam J. Anderson, Lenore Arab, Kweku Bedu-Addo, Stephane Blanc, Alberto G. Bonomi, Pascal Bovet, Soren Brage, Maciej S. Buchowski, Nancy F. Butte, Stefan G.J.A. Camps, Jamie A. Cooper, Richard Cooper, Sai Krupa Das, Peter S. W. Davies, Lara R. Dugas, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W. Fudge, Melanie Gillingham, Santu Ghosh, Annelies H. Goris, Michael Gurven, Lewis G. Halsey, Catherine Hambly, Hinke H. Haisma, Daniel Hoffman, Sumei Hu, Annemiek M. Joosen, Jennifer L. Kaplan, Peter Katzmarzyk, William E. Kraus, Robert F. Kushner, William R. Leonard, Marie Löf, Corby K. Martin, Eric Matsiko, Anine C. Medin, Erwin P. Meijer, Marian L. Neuhouser, Theresa A. Nicklas, Robert M. Ojiambo, Kirsi H. Pietiläinen, Jacob Plange-Rhule, Guy Plasqui, Ross L. Prentice, Susan B. Racette, David A. Raichlen, Eric Ravussin, Leanne M. Redman, Susan B. Roberts, Michael C. Rudolph, Luis B. Sardinha, Albertine J. Schuit, Analiza M. Silva, Eric Stice, Samuel S. Urlacher, Giulio Valenti, Ludo M. Van Etten, Edgar A. Van Mil, Brian M. Wood, Jack A. Yanovski, Tsukasa Yoshida, Xueying Zhang, Alexia J. Murphy-Alford, Cornelia U. Loechl, Anura Kurpad, Amy H. Luke, Herman Pontzer, Matthew S. Rodeheffer, Jennifer Rood, Dale A. Schoeller, William W. Wong
Publikováno v:
Nature Metabolism, 5(4), 579-588. Springer Berlin
Obesity is caused by a prolonged positive energy balance1,2. Whether reduced energy expenditure stemming from reduced activity levels contributes is debated3,4. Here we show that in both sexes, total energy expenditure (TEE) adjusted for body composi
Autor:
Jerrold J. Heindel, Jessica A. Alvarez, Ella Atlas, Matthew C. Cave, Vaia Lida Chatzi, David Collier, Barbara Corkey, Douglas Fischer, Michael I. Goran, Sarah Howard, Scott Kahan, Matthias Kayhoe, Suneil Koliwad, Catherine M. Kotz, Michele La Merrill, Tim Lobstein, Carey Lumeng, David S. Ludwig, Robert H. Lustig, Pete Myers, Angel Nadal, Leonardo Trasande, Leanne M. Redman, Matthew S. Rodeheffer, Robert M. Sargis, Jacqueline M. Stephens, Thomas R. Ziegler, Bruce Blumberg
Publikováno v:
The American Journal of Clinical Nutrition.
Autor:
Zachary L. Sebo, Matthew S. Rodeheffer
Publikováno v:
Stem Cell Reports. 17:1081-1088
Fat distribution is sexually dimorphic and is associated with metabolic disease risk. It is unknown if prepubertal sex-hormone signaling influences adult fat distribution. Here, we show that karyotypically male androgen-insensitive mice exhibit prono