Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Matthew S. Jeffers"'
Autor:
Matthew S. Jeffers, Cheng En Xi, Raj Bapuji, Hannah Wotherspoon, Jonathan Kimmelman, Patrick Bedford, Daniel I. McIsaac, Manoj M. Lalu, Dean A. Fergusson
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Regulatory applications for cell therapy face more objections compared to conventional small molecule or biological drugs, leading to delays in market approval and clinical adoption. Increased regulatory objections frequently rela
Externí odkaz:
https://doaj.org/article/7044491a50f94be9b8a292b7553bc30e
Autor:
Matthew S. Jeffers, Aileen MacLellan, Marc T. Avey, Julia ML Menon, Janet Sunohara-Neilson, Dean A. Fergusson, Manoj M. Lalu
Publikováno v:
PLoS Biology, Vol 21, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/50a01bf3de1148d5a6357078a69d37a2
Autor:
Jessica M. Livingston, Matthew W. McDonald, Therese Gagnon, Matthew S. Jeffers, Mariana Gomez-Smith, Sabina Antonescu, Greg O. Cron, Carlie Boisvert, Baptiste Lacoste, Dale Corbett
Publikováno v:
Neurobiology of Disease, Vol 137, Iss , Pp 104756- (2020)
Vascular cognitive impairment (VCI) is associated with chronic cerebral hypoperfusion (CCH) and memory deficits, and often occurs concurrently with metabolic syndrome (MetS). Despite their common occurrence, it is unknown whether CCH and MetS act syn
Externí odkaz:
https://doaj.org/article/14cd64a64d29470da6ad6f69bec04ca0
Autor:
Gustavo Balbinot, Clarissa Pedrini Schuch, Matthew S. Jeffers, Matthew W. McDonald, Jessica M. Livingston-Thomas, Dale Corbett
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract A coordinated pattern of multi-muscle activation is essential to produce efficient reaching trajectories. Disruption of these coordinated activation patterns, termed synergies, is evident following stroke and results in reaching deficits; ho
Externí odkaz:
https://doaj.org/article/4895a50ebfa6404cba7816bc28ec40a3
Autor:
Matthew W. McDonald, Kathryn S. Hayward, Ingrid C. M. Rosbergen, Matthew S. Jeffers, Dale Corbett
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Environmental enrichment (EE) has been widely used as a means to enhance brain plasticity mechanisms (e.g., increased dendritic branching, synaptogenesis, etc.) and improve behavioral function in both normal and brain-damaged animals. In spite of the
Externí odkaz:
https://doaj.org/article/b5f33ed846b7490ba57fd10f8a8b1d91
Autor:
Matthew S. Jeffers, Alison C. Pittman, Tetyana Kendzerska, Dale Corbett, Kathryn S. Hayward, Yue Chen
Publikováno v:
Canadian Medical Association Journal. 195:E354-E362
Autor:
Jamal Alkadri, Richard Hu, Matthew S. Jeffers, James Ross, Daniel I. McIsaac, Bernard McDonald
Publikováno v:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie.
Autor:
Manoj M. Lalu, Justin Presseau, Madison K. Foster, Victoria T. Hunniford, Kelly D. Cobey, Jamie C. Brehaut, Carolina Ilkow, Joshua Montroy, Analyssa Cardenas, Ayni Sharif, Matthew S. Jeffers, Dean A. Fergusson
Publikováno v:
PLoS biology. 21(1)
Use of rigorous study design methods and transparent reporting in publications are 2 key strategies proposed to improve the reproducibility of preclinical research. Despite promotion of these practices by funders and journals, assessments suggest upt
Autor:
Anthony Carter, Matthew W. McDonald, Gergely Silasi, Matthew S. Jeffers, Angela Dykes, Ralph Nevins, Dale Corbett, Allyson Ripley
Publikováno v:
Neurorehabilitation and Neural Repair
Remote ischemic conditioning (RIC) is a noninvasive procedure whereby several periods of ischemia are induced in a limb. Although there is growing interest in using RIC to improve stroke recovery, preclinical RIC research has focused exclusively on n
Autor:
Cesar H. Comin, Bernard J. Jasmin, Baptiste Lacoste, Allyson Ripley, Matthew W. McDonald, Matthew S. Jeffers, Lydia M. Kuhl, Dale Corbett, Lama Issa, Anthony Carter, Cameron J Morse
Publikováno v:
Neurorehabilitation and Neural Repair
Evidence supports early rehabilitation after stroke to limit disability. However, stroke survivors are typically sedentary and experience significant cardiovascular and muscular deconditioning. Despite growing consensus that preclinical and clinical