Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Matthew S. Hanson"'
Autor:
Juan S. Danobeitia, Matthew S. Hanson, Peter Chlebeck, Elisa Park, Jamie M. Sperger, Alice Schwarznau, Luis A. Fernandez M.D.
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Most pancreas and islet grafts are recovered from brain-dead (BD) donors. In this study we characterized the early inflammatory response induced by brain death in pancreata and islets from nonhuman primate donors and evaluated the effect of targeted
Externí odkaz:
https://doaj.org/article/87157835ac0948188d83c8dc28552b6d
Autor:
John S. Kaddis, Matthew S. Hanson, James Cravens, Dajun Qian, Barbara Olack, Martha Antler, Klearchos K. Papas, Itzia Iglesias, Barbara Barbaro, Luis Fernandez, Alvin C. Powers, Joyce C. Niland Ph.D.
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Preservation of cell quality during shipment of human pancreatic islets for use in laboratory research is a crucial, but neglected, topic. Mammalian cells, including islets, have been shown to be adversely affected by temperature changes in vitro and
Externí odkaz:
https://doaj.org/article/b6bd2ff7770441c48e000052fca668b0
Publikováno v:
Cell Transplantation, Vol 17 (2008)
The objective of this study was to develop a multiparametric flow cytometry assay to simultaneously quantify isolated pancreatic islet cell viability, apoptosis, and glucose-induced metabolic flux. INS-1 and rat islet β-cells were stained with fluor
Externí odkaz:
https://doaj.org/article/c6b4c55011444b04af7de4c4c9a4ca92
Autor:
Martha Antler, Barbara Olack, Alvin C. Powers, James Cravens, Itzia Iglesias, Joyce C. Niland, Luis A. Fernandez, Barbara Barbaro, John S. Kaddis, Klearchos K. Papas, Dajun Qian, Matthew S. Hanson
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Preservation of cell quality during shipment of human pancreatic islets for use in laboratory research is a crucial, but neglected, topic. Mammalian cells, including islets, have been shown to be adversely affected by temperature changes in vitro and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad085522f21861864aa1412bce6ffd6
https://doi.org/10.3727/096368912x653219
https://doi.org/10.3727/096368912x653219
Autor:
Juan S. Danobeitia, Peter J. Chlebeck, Jamie M. Sperger, Mallory L. Sears, Matthew S. Hanson, Elisa E. Park, Alice Schwarznau, Luis A. Fernandez, Drew A. Roenneburg, Jolien X. Connor
Publikováno v:
Journal of Surgical Research. 176:639-648
Background Donor brain death (BD) triggers a systemic inflammatory response that reduces organ quality and increases immunogenicity of the graft. We characterized the early innate immune response induced by BD in the liver and peripheral blood of hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907550b2619b217e5b710366e6577680
https://doi.org/10.1016/j.jss.2011.10.042
https://doi.org/10.1016/j.jss.2011.10.042
Autor:
Rodolfo Alejandro, David A. Baidal, Nancy Radke, Jon S. Odorico, Luis A. Fernandez, Juan S. Danobeitia, D. Hirsch, Michael R. Rickels, Dixon B. Kaufman, Debra A. Hullett, Ali Naji, Matthew S. Hanson, Camillo Ricordi
Publikováno v:
American Journal of Transplantation. 12:1275-1289
The objective of this study was to identify predictors of insulin independence and to establish the best clinical tools to follow patients after pancreatic islet transplantation (PIT). Sequential metabolic responses to intravenous (I.V.) glucose (I.V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af5ad1762fe27c8938ec76086581fc1
https://doi.org/10.1111/j.1600-6143.2011.03947.x
https://doi.org/10.1111/j.1600-6143.2011.03947.x
Autor:
Michael J. MacDonald, Toshiyuki Fukao, Sarawut Jitrapakdee, Melissa J. Longacre, Ansaya Thonpho, Luis A. Fernandez, Mindy A. Kendrick, Noaman Hasan, Jon S. Odorico, Scott W. Stoker, Laura J. Brown, Matthew S. Hanson
Publikováno v:
Journal of Biological Chemistry. 286:18383-18396
Anaplerosis, the net synthesis in mitochondria of citric acid cycle intermediates, and cataplerosis, their export to the cytosol, have been shown to be important for insulin secretion in rodent beta cells. However, human islets may be different. We o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb79cb2a96c123867e88439fa22a48e4
https://doi.org/10.1074/jbc.m111.241182
https://doi.org/10.1074/jbc.m111.241182
Autor:
Nancy Radke, Rodolfo Alejandro, D. Hirsch, Juan S. Danobeitia, Matthew S. Hanson, Jon S. Odorico, Camillo Ricordi, Luis A. Fernandez, Debra A. Hullett
Publikováno v:
Diabetes, Obesity and Metabolism. 12:994-1003
Aims: Pancreatic islet transplantation (PIT) represents a potential curative treatment for patients with type 1 diabetes, but only 10-15% of patients remain insulin independent 5 years post-transplant. It is not known whether intrinsic insulin resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5358cbd667692784357927bc29cb338b
https://doi.org/10.1111/j.1463-1326.2010.01290.x
https://doi.org/10.1111/j.1463-1326.2010.01290.x
Autor:
Mallory L. Sears, Elisa E. Park, Matthew S. Hanson, Debra A. Hullett, Luis A. Fernandez, Krista K. Greenwood, Juan S. Danobeitia
Publikováno v:
Transplantation. 89:1178-1188
Background The successful treatment of patients with type 1 diabetes by islet transplantation is affected by a multitude of factors of which infusion of the highest quality tissue is essential. The current standard pretransplant quality assessments l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfec8d718c491fd89f2ee0019c3ca9a7
https://doi.org/10.1097/tp.0b013e3181d54bce
https://doi.org/10.1097/tp.0b013e3181d54bce
Publikováno v:
American Journal of Transplantation. 7:38-47
We have developed a luminol-based assay using intact islets, which allows for quantification of reactive oxygen species (ROS). In addition, an index capable of characterizing metabolic and mitochondrial integrity prior to transplantation was created
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2d2517577095d737d5618a863007e4
https://doi.org/10.1111/j.1600-6143.2006.01577.x
https://doi.org/10.1111/j.1600-6143.2006.01577.x