Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthew S. Graus"'
Autor:
Caroline T. Seebauer, Matthew S. Graus, Lan Huang, Alex McCann, Jill Wylie-Sears, Frank Fontaine, Tara Karnezis, David Zurakowski, Steven J. Staffa, Frédéric Meunier, John B. Mulliken, Joyce Bischoff, Mathias Francois
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
Propranolol and atenolol, current therapies for problematic infantile hemangioma (IH), are composed of R(+) and S(–) enantiomers: the R(+) enantiomer is largely devoid of beta blocker activity. We investigated the effect of R(+) enantiomers of prop
Externí odkaz:
https://doaj.org/article/5e6caa76ca894a93a267f1f0dc061b4f
Autor:
Kristen Feher, Matthew S. Graus, Simao Coelho, Megan V. Farrell, Jesse Goyette, Katharina Gaus
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2021)
Single molecule localisation microscopy (SMLM) is a powerful tool that has revealed the spatial arrangement of cell surface signalling proteins, producing data of enormous complexity. The complexity is partly driven by the convolution of technical an
Externí odkaz:
https://doaj.org/article/22dc07f67622419abb6aca0a7dceedb2
Autor:
Ivy K N Chiang, Matthew S Graus, Nils Kirschnick, Tara Davidson, Winnie Luu, Richard Harwood, Keyi Jiang, Bitong Li, Yew Yan Wong, Mehdi Moustaqil, Emmanuelle Lesieur, Renae Skoczylas, Valerie Kouskoff, Jan Kazenwadel, Luis Arriola‐Martinez, Emma Sierecki, Yann Gambin, Kari Alitalo, Friedmann Kiefer, Natasha L Harvey, Mathias Francois
Refereed/Peer-reviewed Despite a growing catalog of secreted factors critical for lymphatic network assembly, little is known about the mechanisms that modulate the expression level of these molecular cues in blood vascular endothelial cells (BECs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b743e950455b85e2c844ab2d4d566703
https://hdl.handle.net/11541.2/32559
https://hdl.handle.net/11541.2/32559
Autor:
Mehdi Moustaqil, Frederic A. Meunier, Alex Jade McCann, Frank Fontaine, Yann Gambin, Peter Koopman, Ailisa Blum, Winnie Luu, Jieqiong Lou, Hui Liu, Mathias Francois, Matthew S Graus, Paulina Rudolffi-Soto, Zhe Liu, Emma Sierecki, Elizabeth Hinde
Publikováno v:
Nucleic Acids Research
Few genetically dominant mutations involved in human disease have been fully explained at the molecular level. In cases where the mutant gene encodes a transcription factor, the dominant-negative mode of action of the mutant protein is particularly p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23264690e289c3a75afda1ee8736b435
http://europepmc.org/articles/PMC8565327
http://europepmc.org/articles/PMC8565327
Autor:
Caroline T. Seebauer, Matthew S. Graus, Lan Huang, Alex McCann, Sears Jill Wylie, Frank Fontaine, Tara Karnezis, David Zurakowski, Steven J. Staffa, John B. Mulliken, Joyce Bischoff, Mathias Francois
Publikováno v:
Abstract- und Posterband - 93. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn Interface - Fokus Mensch im Zeitalter der technisierten Medizin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2afb5b135f9c3b39569adaaa3bf60e4d
https://doi.org/10.1055/s-0042-1747539
https://doi.org/10.1055/s-0042-1747539
Autor:
Michelle S Itano, Matthew S Graus, Carolyn ePehlke, Michael J Wester, Ping eLiu, Keith A Lidke, Nancy L Thompson, Ken eJacobson, Aaron K Neumann
Publikováno v:
Frontiers in Physics, Vol 2 (2014)
Dendritic cells express DC-SIGN and CD206, C-type lectins (CTLs) that bind a variety of pathogens and may facilitate pathogen uptake for subsequent antigen presentation. Both proteins form punctate membrane nanodomains (~80 nm) on naïve cells. We an
Externí odkaz:
https://doaj.org/article/3b53ccae7b03414281af8451095170f7
Autor:
Matthew S Graus, Carolyn Pehlke, Michael J Wester, Lisa B Davidson, Stanly L Steinberg, Aaron K Neumann
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 5, p e1003639 (2014)
To understand the process of innate immune fungal recognition, we developed computational tools for the rigorous quantification and comparison of receptor recruitment and distribution at cell-cell contact sites. We used these tools to quantify patter
Externí odkaz:
https://doaj.org/article/263374a4f4324948a34b06a4e2caeeef
Autor:
Jesse Goyette, Rashmi R. Pillai, Varun K. A. Sreenivasan, Matthew S. Graus, Zhengmin Yang, Katharina Gaus
Publikováno v:
Biomed Opt Express
Protein-protein interactions at the plasma membrane mediate transmembrane signaling. Dual-channel fluorescence cross-correlation spectroscopy (dc-FCCS) is a method with which these interactions can be quantified in a cellular context. However, factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5172951d213a18016b3a3128dcb674c6
https://pubmed.ncbi.nlm.nih.gov/33282480
https://pubmed.ncbi.nlm.nih.gov/33282480
Autor:
Matthew S. Graus, Jongho Baek, Kristen Feher, Simao Coelho, Philip R. Nicovich, James M Halstead, Hetvi Gandhi, Katharina Gaus, J. Justin Gooding
Publikováno v:
Science Advances
Feedback SMLM achieves ultrahigh localization precision and in situ distance measurements on the biological relevant scales.
Single-molecule localization microscopy (SMLM) has the potential to quantify the diversity in spatial arrangements of mo
Single-molecule localization microscopy (SMLM) has the potential to quantify the diversity in spatial arrangements of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84964bf3e2e670b5a678d53b28f896a7
https://pubmed.ncbi.nlm.nih.gov/32494604
https://pubmed.ncbi.nlm.nih.gov/32494604
Autor:
Patrick L. Donabedian, David G. Whitten, Harry C. Pappas, Matthew S. Graus, Aaron K. Neumann, Rina Sylejmani
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:4519-4529
Candida species are the cause of many bloodstream infections through contamination of indwelling medical devices. These infections account for a 40% mortality rate, posing a significant risk to immunocompromised patients. Traditional treatments again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9eaf6f3b56034b7c68d9b88def6858
https://doi.org/10.1128/aac.00317-16
https://doi.org/10.1128/aac.00317-16