Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Matthew S. Bryant"'
Publikováno v:
Chemical Research in Toxicology. 36:243-250
Autor:
Xilin Li, Xiaobo He, Yuan Le, Xiaoqing Guo, Matthew S. Bryant, Aisar H. Atrakchi, Timothy J. McGovern, Karen L. Davis-Bruno, David A. Keire, Robert H. Heflich, Nan Mei
Publikováno v:
Archives of Toxicology. 96:3077-3089
Autor:
Xilin, Li, Xiaobo, He, Yuan, Le, Xiaoqing, Guo, Matthew S, Bryant, Aisar H, Atrakchi, Timothy J, McGovern, Karen L, Davis-Bruno, David A, Keire, Robert H, Heflich, Nan, Mei
Publikováno v:
Archives of toxicology. 96(11)
Many nitrosamines are recognized as mutagens and potent rodent carcinogens. Over the past few years, nitrosamine impurities have been detected in various drugs leading to drug recalls. Although nitrosamines are included in a 'cohort of concern' becau
Autor:
Darshan Mehta, Miao Li, Noriko Nakamura, Mani Chidambaram, Xiaobo He, Matthew S. Bryant, Ralph Patton, Kelly Davis, Jeffrey Fisher
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 111
Although the use of medication during pregnancy is common, information on exposure to the developing fetus and potential teratogenic effects is often lacking. This study used a rat model to examine the placental transfer of three small-molecule drugs
Autor:
Shu-Chieh Hu, Seonggi Min, Hyun-Ki Kang, Dong-Jin Yang, Mallikarjuna Basavarajappa, Sherry M. Lewis, Kelly J. Davis, Ralph E. Patton, Matthew S. Bryant, Estatira Sepehr, Raul Trbojevich, Mason G. Pearce, Michelle E. Bishop, Wei Ding, Robert H. Heflich, MacKean P. Maisha, Robert Felton, Susan Chemerynski, Steven B. Yee, Melis Coraggio, Hans Rosenfeldt, R. Philip Yeager, Paul C. Howard, Yunan Tang
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 160
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is one of the key tobacco-specific nitrosamines that plays an important role in human lung carcinogenesis. Repeated dose inhalation toxicity data on NNK, particularly relevant to cigarette smoking,
Autor:
Yiying, Wang, Qiangen, Wu, Levan, Muskhelishvili, Kelly, Davis, Rebecca, Wynne, Priya, Tripathi, Matthew S, Bryant, Diego, Rua, Xuefei, Cao
Publikováno v:
Chemical research in toxicology. 34(3)
Ortho-phthalaldehyde (OPA) is a chemical disinfectant used for the high-level sterilization of heat-sensitive medical instruments. Although OPA is considered a safer alternative to glutaraldehyde, no exposure limits have been established for respirat
Publikováno v:
Environmental Epidemiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeacbaba7d848f47b87a18dc7ceefa42
https://doi.org/10.1201/9780367810870-5
https://doi.org/10.1201/9780367810870-5
Publikováno v:
Rapid Communications in Mass Spectrometry. 19:1943-1950
Bioanalytical support of plasma pharmacokinetic (PK) studies for drug discovery programs primarily involves the quantitative analysis of dosed compounds using liquid chromatography/atmospheric pressure ionization tandem mass spectrometry (LC/MS/MS) o
Publikováno v:
Rapid Communications in Mass Spectrometry. 18:2343-2350
Isoniazid and cetirizine do not retain well on reversed-phase columns due to their high polarity. Silica columns, when operated under hydrophilic interaction conditions, do provide excellent retention of these compounds. We have developed simple and
Autor:
Shirley M. Williams, Matthew S. Bryant, Mccormick Kevin D, John A. Hey, L. M. Varty, Garfield G. Mingo, Robert G. Aslanian, Neng-Yang Shih, Yunsheng Hsieh, Walter A. Korfmacher, Robert E. West, Robbie L. McLeod, Robert W. Egan, Charlie A. Rizzo
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:1037-1044
We present the pharmacological and pharmacokinetic profiles of a novel histamine H3 receptor antagonist, N-(3,5-dichlorophenyl)-N′-[[4-(1H-imidazol-4-ylmethyl)phenyl]-methyl]-urea (SCH 79687). The H3-receptor binding Ki values for SCH 79687 were 1.