Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Matthew S. Brook"'
Autor:
Natalie F. Shur, Elizabeth J. Simpson, Hannah Crossland, Despina Constantin, Sally M. Cordon, Dumitru Constantin‐Teodosiu, Francis B. Stephens, Matthew S. Brook, Philip J. Atherton, Kenneth Smith, Daniel J. Wilkinson, Olivier E. Mougin, Christopher Bradley, Ian A. Macdonald, Paul L. Greenhaff
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 603-614 (2024)
Abstract Background Bed‐rest (BR) of only a few days duration reduces muscle protein synthesis and induces skeletal muscle atrophy and insulin resistance, but the scale and juxtaposition of these events have not been investigated concurrently in th
Externí odkaz:
https://doaj.org/article/d580a30a9b8542378951c31db57ce3e4
Autor:
Matthew S. Brook, Tanner Stokes, Stefan H.M. Gorissen, Joseph J. Bass, Chris McGlory, Jessica Cegielski, Daniel J. Wilkinson, Bethan E. Phillips, Ken Smith, Stuart M. Phillips, Philip J. Atherton
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2005-2016 (2022)
Abstract Background We determined the short‐term (i.e. 4 days) impacts of disuse atrophy in relation to muscle protein turnover [acute fasted‐fed muscle protein synthesis (MPS)/muscle protein breakdown (MPB) and integrated MPS/estimated MPB]. Met
Externí odkaz:
https://doaj.org/article/27b1f69c856247ca8b2a4d28ec34564f
Autor:
Nima Gharahdaghi, Supreeth Rudrappa, Matthew S. Brook, Wesam Farrash, Iskandar Idris, Muhammad Hariz Abdul Aziz, Fawzi Kadi, Konstantinos Papaioannou, Bethan E. Phillips, Tanvir Sian, Philip J. Herrod, Daniel J. Wilkinson, Nathaniel J. Szewczyk, Kenneth Smith, Philip J. Atherton
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1134-1150 (2022)
Abstract Background The relative role of skeletal muscle mechano‐transduction in comparison with systemic hormones, such as testosterone (T), in regulating hypertrophic responses to exercise is contentious. We investigated the mechanistic effects o
Externí odkaz:
https://doaj.org/article/64719bb9cf8640d18f2490a529924d9c
Autor:
James E.M. Blackwell, Nima Gharahdaghi, Matthew S. Brook, Shinya Watanabe, Catherine L. Boereboom, Brett Doleman, Jonathan N. Lund, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, John P. Williams, Bethan E. Phillips
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 4, Pp 866-879 (2021)
Abstract Background Declines in cardiorespiratory fitness (CRF) and fat‐free mass (FFM) with age are linked to mortality, morbidity and poor quality of life. High‐intensity interval training (HIIT) has been shown to improve CRF and FFM in many gr
Externí odkaz:
https://doaj.org/article/2e48ca71949d4702b72e53eaf97a0ff8
Publikováno v:
Clinical Nutrition Open Science, Vol 45, Iss , Pp 112- (2022)
Externí odkaz:
https://doaj.org/article/ca3f78aa57af4898bfb84def33b457bd
Publikováno v:
Clinical Nutrition Open Science, Vol 36, Iss , Pp 111-125 (2021)
Summary: The key to understanding the mechanisms regulating disease stems from the ability to accurately quantify the dynamic nature of the metabolism underlying the physiological and pathological changes occurring as a result of the disease. Stable
Externí odkaz:
https://doaj.org/article/84ae585ace9e4f18963cc2b063faa9ee
Autor:
Benoit Smeuninx, Yasir S. Elhassan, Konstantinos N. Manolopoulos, Elizabeth Sapey, Alison B. Rushton, Sophie J. Edwards, Paul T. Morgan, Andrew Philp, Matthew S. Brook, Nima Gharahdaghi, Kenneth Smith, Philip J. Atherton, Leigh Breen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 52-69 (2021)
Abstract Background Poor recovery from periods of disuse accelerates age‐related muscle loss, predisposing individuals to the development of secondary adverse health outcomes. Exercise prior to disuse (prehabilitation) may prevent muscle deteriorat
Externí odkaz:
https://doaj.org/article/dd767f5982414a148eda2a2db9a28333
Autor:
Christopher G. Vann, Casey L. Sexton, Shelby C. Osburn, Morgan A. Smith, Cody T. Haun, Melissa N. Rumbley, Petey W. Mumford, Nathan T. Montgomery, Bradley A. Ruple, James McKendry, Jonathan Mcleod, Adil Bashir, Ronald J. Beyers, Matthew S. Brook, Kenneth Smith, Philip J. Atherton, Darren T. Beck, James R. McDonald, Kaelin C. Young, Stuart M. Phillips, Michael D. Roberts
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
We evaluated the effects of higher-load (HL) versus (lower-load) higher-volume (HV) resistance training on skeletal muscle hypertrophy, strength, and muscle-level molecular adaptations. Trained men (n = 15, age: 23 ± 3 years; training experience: 7
Externí odkaz:
https://doaj.org/article/5aa99eb02ed84b8f8de7ffd18497c62f
Autor:
Nima Gharahdaghi, Supreeth Rudrappa, Matthew S. Brook, Iskandar Idris, Hannah Crossland, Claire Hamrock, Muhammad Hariz Abdul Aziz, Fawzi Kadi, Janelle Tarum, Paul L. Greenhaff, Dumitru Constantin‐Teodosiu, Jessica Cegielski, Bethan E. Phillips, Daniel J. Wilkinson, Nathaniel J. Szewczyk, Kenneth Smith, Philip J. Atherton
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 6, Pp 1276-1294 (2019)
Abstract Background The andropause is associated with declines in serum testosterone (T), loss of muscle mass (sarcopenia), and frailty. Two major interventions purported to offset sarcopenia are anabolic steroid therapies and resistance exercise tra
Externí odkaz:
https://doaj.org/article/1ebefde7779242ebbdc0bf779b91f2aa
Autor:
Rita Civil, Matthew S. Brook, Kirsty J. Elliott‐Sale, Lívia Santos, Ian Varley, Sanna Lensu, Heikki Kainulainen, Lauren G. Koch, Steven L. Britton, Daniel J. Wilkinson, Kenneth Smith, Craig Sale, Philip J. Atherton
Publikováno v:
Physiological Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract The development of safe and practical strategies to prevent weakening of bone tissue is vital, yet attempts to achieve this have been hindered by a lack of understanding of the short‐term (days‐weeks) physiology of bone collagen turnover
Externí odkaz:
https://doaj.org/article/687d13d28dcf45149dd60441f6e198d0