Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Matthew S Lawrence"'
Autor:
Jeffrey O’Callaghan, Conor Delaney, Merissa O’Connor, Joseph van Batenburg-Sherwood, Martin Schicht, Elke Lütjen-Drecoll, Natalie Hudson, Sorcha Ni Dhubhghaill, Peter Humphries, Chris Stanley, Annahita Keravala, Thomas Chalberg, Matthew S. Lawrence, Matthew Campbell
Publikováno v:
Science Advances
Approximately 80 million people globally are affected by glaucoma, with a projected increase to over 110 million by 2040. Substantial issues surrounding patient compliance remain with topical eye drops, and up to 10% of patients become treatment resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2163670e3efbc40f0669a05cfbd865
https://doi.org/10.1126/sciadv.adf6537
https://doi.org/10.1126/sciadv.adf6537
Publikováno v:
Journal of Maritime Archaeology. 16:223-251
The barque Vicar of Bray (1842) is a historically well-documented vessel which has transitioned from a beached hulk to a shipwreck at Goose Green in the Falkland Islands. The barque’s historical and archaeological contexts and its ties to the emerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0634a8e86748bb95b4fecf9666cc1b15
https://doi.org/10.1007/s11457-021-09298-w
https://doi.org/10.1007/s11457-021-09298-w
Autor:
Dustin R. Wakeman, Michael R. Weed, Sylvia E. Perez, Erika N. Cline, Kirsten L. Viola, Kyle C. Wilcox, David S. Moddrelle, Ernell Z. Nisbett, Anish M. Kurian, Amanda F. Bell, Ricaldo Pike, Peer B. Jacobson, William L. Klein, Elliott J. Mufson, Matthew S. Lawrence, John D. Elsworth
Publikováno v:
Neuropathology and applied neurobiologyREFERENCES. 48(4)
An obstacle to developing new treatment strategies for Alzheimer's disease (AD) has been the inadequate translation of findings in current AD transgenic rodent models to the prediction of clinical outcomes. By contrast, nonhuman primates (NHPs) share
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e008c988d7d44fd1dd22787c703de9e0
https://pubmed.ncbi.nlm.nih.gov/35156715
https://pubmed.ncbi.nlm.nih.gov/35156715
Autor:
Donnicia James, Anish Kurian, Chintan Patel, Lori-Ann Christie, Thomas C. Hohman, Wenzheng Hu, Matthew S Lawrence, Richard Torres, Robin J Goody
Publikováno v:
Exp Eye Res
The purpose of this study was to characterize and develop a primate model of chronic retinal neovascularization and vascular leakage that can be employed to assess efficacy of experimental therapeutics targeting retinal ischemic and neovascular disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a490ff26080236809ae0de0a348599af
https://europepmc.org/articles/PMC7335215/
https://europepmc.org/articles/PMC7335215/
Publikováno v:
International Journal of Nautical Archaeology. 46:149-163
During 2015, the NOAA Office of National Marine Sanctuaries led a systematic seabed mapping survey along the Arctic coast of Alaska in search of whaling ships abandoned in 1871. The purpose of the expedition was to determine if wreckage from these ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::040f4aa9d26ebe787cb6882043f538fb
https://doi.org/10.1111/1095-9270.12205
https://doi.org/10.1111/1095-9270.12205
Autor:
Ema Ozaki, Sofia Theodoropoulou, Matthew Campbell, Akeem Browne, Federica Storti, Erin Fahey, Chris H. Greene, Shervin Liddie, Alan Hopkins, Mark Cahill, Marian M. Humphries, Eleanor Demmons, Paul F. Kenna, Christian Grimm, Sarah L. Doyle, Anne M. Curtis, Matthew S. Lawrence, Peter Humphries, Lucia Celkova, Natalie Hudson
Publikováno v:
Hudson, N, Celkova, L, Hopkins, A, Greene, C, Storti, F, Ozaki, E, Fahey, E, Theodoropoulou, S, Kenna, P F, Humphries, M M, Curtis, A M, Demmons, E, Browne, A, Liddie, S, Lawrence, M S, Grimm, C, Cahill, M T, Humphries, P, Doyle, S L & Campbell, M 2019, ' Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy ', JCI Insight, vol. 4, no. 15, 130273 . https://doi.org/10.1172/jci.insight.130273
Age-related macular degeneration (AMD) is the leading cause of central retinal vision loss worldwide, with an estimated 1 in 10 people over the age of 55 showing early signs of the condition. There are currently no forms of therapy available for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6e73e0d8f14543916d8e047e70781b
https://europepmc.org/articles/PMC6693834/
https://europepmc.org/articles/PMC6693834/
Autor:
Paul Halley, Marco Magistri, Beena M. Kadakkuzha, Mohammad Ali Faghihi, Claes Wahlestedt, Zane Zeier, Carlos Coito, Olga Khorkova, Matthew S Lawrence, Jane Hsiao
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 222-230 (2014)
SummaryApolipoprotein A1 (APOA1) is the major protein component of high-density lipoprotein (HDL) in plasma. We have identified an endogenously expressed long noncoding natural antisense transcript, APOA1-AS, which acts as a negative transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ea174c8928a2fa379acb73a65ec85b
https://doi.org/10.1016/j.celrep.2013.12.015
https://doi.org/10.1016/j.celrep.2013.12.015
Autor:
Darragh E. Crosbie, Anna-Sophia Kiang, Matthew S. Lawrence, Elke Lütjen-Drecoll, Colm O'Brien, Jeffrey O'Callaghan, Kristin Perkumas, Ester Reina-Torres, W. Daniel Stamer, Marian M. Humphries, Joseph M. Sherwood, Matthew Campbell, John J. Callanan, Lawrence C. S. Tam, Darryl R. Overby, Cassandra Flügel-Koch, Peter Humphries, Paul S. Cassidy, A. Thomas Read, C. Ross Ethier
Publikováno v:
Scientific Reports
The juxtacanalicular connective tissue of the trabecular meshwork together with inner wall endothelium of Schlemm’s canal (SC) provide the bulk of resistance to aqueous outflow from the anterior chamber. Endothelial cells lining SC elaborate tight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fc806f8671f157845801d0b0cd1bf6
https://pubmed.ncbi.nlm.nih.gov/28091584
https://pubmed.ncbi.nlm.nih.gov/28091584
Autor:
Julia Strathmann, John D. Elsworth, Robert H. Roth, Claes Wahlestedt, David Willoughby, Matthew S Lawrence, Thomas A. Lanz, Brooke H. Miller, Paul J. Kenny, Li Xi, Shibing Deng, Robin J. Kleiman, Dieter Edbauer, Zane Zeier
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 109(8), 3125-3130 (2012). doi:10.1073/pnas.1113793109
Schizophrenia is characterized by affective, cognitive, neuromorphological, and molecular abnormalities that may have a neurodevelopmental origin. MicroRNAs (miRNAs) are small noncoding RNA sequences critical to neurodevelopment and adult neuronal pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6dfe8e4b2fbf333367e5ade41fc7160
https://doi.org/10.1073/pnas.1113793109
https://doi.org/10.1073/pnas.1113793109
Autor:
Afshin Shafiee, Robin J Goody, Stephen P. Bartels, Francisco J. López, Wenzheng Hu, Michael Struharik, Matthew S Lawrence
Publikováno v:
Experimental Eye Research. 92:464-472
We developed and validated a new nonhuman primate model of laser-induced choroidal neovascularization (CNV) that addresses study design limitations prevalent in laser-induced CNV-based efficacy studies. Laser-induced Bruch’s membrane disruption tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b209bdb4d4c5eeac9485cb17cc8b5909
https://doi.org/10.1016/j.exer.2011.03.006
https://doi.org/10.1016/j.exer.2011.03.006