Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Matthew S Holdren"'
Autor:
W. Tony Parks, Jean S. Campbell, Gabriela D. Guncay, Annie Liu, José Mordoh, Estrella Levy, Michele Bianchini, Momoko H. Furuya, Anthony P. Nguyen, Matthew S. Holdren, Lananh N. Nguyen
Supplementary Table 1 from Sorting Nexin 1 Down-Regulation Promotes Colon Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812cef897ce0f0073b713afc846cfd20
https://doi.org/10.1158/1078-0432.22441384
https://doi.org/10.1158/1078-0432.22441384
Autor:
W. Tony Parks, Jean S. Campbell, Gabriela D. Guncay, Annie Liu, José Mordoh, Estrella Levy, Michele Bianchini, Momoko H. Furuya, Anthony P. Nguyen, Matthew S. Holdren, Lananh N. Nguyen
Purpose: Colon cancer is one of the most common human malignancies, yet studies have only begun to identify the multiple mechanisms that underlie the development of this tumor. In this study, we have identified a novel mechanism, dysregulation of end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3231093391adbe3c8213eee054144fa4
https://doi.org/10.1158/1078-0432.c.6518464
https://doi.org/10.1158/1078-0432.c.6518464
Autor:
Katherine E. Lewis, Mark J. Selby, Gregg Masters, Jose Valle, Gennaro Dito, Wendy R. Curtis, Richard Garcia, Kathy A. Mink, Kimberly S. Waggie, Matthew S. Holdren, Joseph F. Grosso, Alan J. Korman, Maria Jure-Kunkel, Stacey R. Dillon
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
Recent advances in cancer treatment with checkpoint blockade of receptors such as CTLA-4 and PD-1 have demonstrated that combinations of agents with complementary immunomodulatory effects have the potential to enhance antitumor activity as compared t
Externí odkaz:
https://doaj.org/article/54e3b8070e6e4ea1b4254c709405e4a3
Autor:
Yan Wu, Jean-Michel Vernes, Wei-Ching Liang, Karla Lancaster, Melissa Schutten, Y. Gloria Meng, Gopinath S. Palanisamy, Rutwij A. Dave, Matthew S Holdren, Adeyemi O Adedeji, Fiona Zhong, Mayur S. Mitra, Shannon J. Turley
Publikováno v:
Toxicological Sciences. 175:24-34
Transforming growth factor β (TGFβ) signaling has been recently shown to reduce antitumor response to PD-L1 blockade, leading to a renewed enthusiasm in developing anti-TGFβ therapies for potential combination with cancer immunotherapy agents. Inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93edf8656b6bd4003a8a622169a138a7
https://doi.org/10.1093/toxsci/kfaa024
https://doi.org/10.1093/toxsci/kfaa024
Autor:
Susan H. Julien, Kelly Byrnes-Blake, Jeremy A Freeman, Katherine E. Lewis, Mark W. Rixon, Matthew S. Holdren, M.F. Maurer, Brent Meengs, Stacey R. Dillon, S. Underwood, Thomas R. Bukowski, Nels Hamacher, A.C. Wolf
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 31:142-150
Background Overexpression or administration of interleukin 31 (IL-31) has been shown to induce a profound itch response in mice and dogs. The chronic pruritus observed in mouse IL-31 transgenic mice results in the development of skin lesions and alop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a467f62858b148afbeda19d209f05236
https://doi.org/10.1111/jdv.13794
https://doi.org/10.1111/jdv.13794
Autor:
Joseph F. Grosso, Stacey R. Dillon, Kimberly S Waggie, Wendy R Curtis, Gennaro Dito, Mark J. Selby, Jose Valle, Richard Garcia, Katherine E. Lewis, Alan J. Korman, Kathy A Mink, Gregg Masters, Matthew S. Holdren, Maria Jure-Kunkel
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
Oncoimmunology
Oncoimmunology
Recent advances in cancer treatment with checkpoint blockade of receptors such as CTLA-4 and PD-1 have demonstrated that combinations of agents with complementary immunomodulatory effects have the potential to enhance antitumor activity as compared t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732a94cf3361d3e83735b8c5e27a6bab
https://doaj.org/article/54e3b8070e6e4ea1b4254c709405e4a3
https://doaj.org/article/54e3b8070e6e4ea1b4254c709405e4a3
Autor:
Helen G. Haggerty, Matthew S. Holdren, R. Daniel Mellon, Rafael Ponce, Herve Lebrec, Shawn Heidel, Thomas Gelzleichter, Marc Pallardy
Publikováno v:
Journal of Immunotoxicology. 11:1-12
Observational and clinical studies have associated increased cancer risks with primary or acquired immunodeficiencies, autoimmunity, and use of immunotherapies to treat chronic inflammation (e.g. autoimmunity) or support organ engraftment. Understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb931be0464fece0d57d180d92f97bff
https://doi.org/10.3109/1547691x.2013.798388
https://doi.org/10.3109/1547691x.2013.798388
Autor:
Momoko H. Furuya, Jean S. Campbell, Nelson Fausto, Lawrence A. Wolfraim, Matthew S. Holdren, W. Tony Parks, Anthony P. Nguyen, Lananh N. Nguyen, George C.T. Yeoh, Belinda Knight
Publikováno v:
Hepatology. 45:31-41
Oval cells are hepatocytic precursors that proliferate in late-stage cirrhosis and that give rise to a subset of human hepatocellular carcinomas. Although liver regeneration typically occurs through replication of existing hepatocytes, oval cells pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daadf84393960150f6f79f728ead357
https://doi.org/10.1002/hep.21466
https://doi.org/10.1002/hep.21466
Autor:
Matthew Yeh, Steven D. Hughes, Hong-Ping Ren, Thomas E. Palmer, Melissa M. Odell, Jean S. Campbell, Renay L. Bauer, Debra G. Gilbertson, Harald S. Haugen, Aaron C. Haran, Nelson Fausto, Matthew S. Holdren
Publikováno v:
Proceedings of the National Academy of Sciences. 102:3389-3394
Members of the platelet-derived growth factor (PDGF) ligand family are known to play important roles in wound healing and fibrotic disease. We show that both transient and stable expression of PDGF-C results in the development of liver fibrosis consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75058c0045218cb3ccb0453c6848b95
https://doi.org/10.1073/pnas.0409722102
https://doi.org/10.1073/pnas.0409722102
Autor:
Elif G. Sozmen, W. Tony Parks, Judith Romero-Gallo, William E. Russell, Shiva Gautam, Harold L. Moses, Anna Chytil, Matthew S. Holdren, Momoko F Her, William M. Grady, Robert H. Whitehead, Mark A. Magnuson
Publikováno v:
Oncogene. 24:3028-3041
The transforming growth factor beta (TGF-beta) signaling pathway, which is activated by the TGF-beta receptor complex consisting of type I and type II TGF-beta receptors (TGFBR1 and TGFBR2), regulates cell growth and death. TGF-beta and components of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1452141f50e12be06d785029873bd322
https://doi.org/10.1038/sj.onc.1208475
https://doi.org/10.1038/sj.onc.1208475