Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Matthew S Grubb"'
Autor:
Elisa Galliano, Eleonora Franzoni, Marine Breton, Annisa N Chand, Darren J Byrne, Venkatesh N Murthy, Matthew S Grubb
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/55f8952da8004630ad0373af9bb4eb43
Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron
Autor:
Elisa Galliano, Eleonora Franzoni, Marine Breton, Annisa N Chand, Darren J Byrne, Venkatesh N Murthy, Matthew S Grubb
Publikováno v:
eLife, Vol 7 (2018)
Most neurogenesis in the mammalian brain is completed embryonically, but in certain areas the production of neurons continues throughout postnatal life. The functional properties of mature postnatally generated neurons often match those of their embr
Externí odkaz:
https://doaj.org/article/58e14dc476a74fd98c4dd40d85a1f906
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
The axon initial segment (AIS) is a specialised neuronal compartment involved in the maintenance of axo-dendritic polarity and in the generation of action potentials. It is also a site of significant structural plasticity – manipulations of neurona
Externí odkaz:
https://doaj.org/article/9ba1a217ca9042bb8e0bdefb5d63109a
Autor:
Matthew S Grubb, Juan Burrone
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13761 (2010)
The light-gated cation channel Channelrhodopsin-2 (ChR2) is a powerful and versatile tool for controlling neuronal activity. Currently available versions of ChR2 either distribute uniformly throughout the plasma membrane or are localised specifically
Externí odkaz:
https://doaj.org/article/b5804bbd1ed84ab3920c4f0408bf2db1
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100146- (2020)
Summary: Obtaining electrophysiological recordings and gene expression information from the same neuron (Patch-seq) brings forward a unique opportunity to study the transcriptional correlates of functional properties and vice versa. Here, we provide
Externí odkaz:
https://doaj.org/article/7cbaee99283b4f07be46e69affe7b93e
Publikováno v:
Cell Reports, Vol 13, Iss 6, Pp 1233-1245 (2015)
Neurons implement a variety of plasticity mechanisms to alter their function over timescales ranging from seconds to days. One powerful means of controlling excitability is to directly modulate the site of spike initiation, the axon initial segment (
Externí odkaz:
https://doaj.org/article/596be47e16df449e92a56ecdb24a044b
Autor:
Candida Tufo, Subathra Poopalasundaram, Ana Dorrego-Rivas, Marc C. Ford, Anthony Graham, Matthew S. Grubb
Publikováno v:
Development
The mammalian main olfactory bulb is a crucial processing centre for the sense of smell. The olfactory bulb forms early during development and is functional from birth. However, the olfactory system continues to mature and change throughout life as a
Publikováno v:
bioRxiv
European Journal of Neuroscience
European Journal of Neuroscience
In the glomerular layer of the olfactory bulb, local dopaminergic interneurons play a key role in regulating the flow of sensory information from nose to cortex. These dual dopamine- and GABA-releasing cells are capable of marked experience-dependent
Autor:
Marcela, Lipovsek, Matthew S, Grubb
Publikováno v:
The EMBO Journal
Adult neurogenesis is involved in cognitive performance but studies that manipulated this process to improve brain function are scarce. Here, we characterized a genetic mouse model in which neural stem cells (NSC) of the subventricular zone (SVZ) wer
Publikováno v:
STAR Protocols
STAR Protocols, Vol 1, Iss 3, Pp 100146-(2020)
Star Protocols
STAR Protocols, Vol 1, Iss 3, Pp 100146-(2020)
Star Protocols
Summary Obtaining electrophysiological recordings and gene expression information from the same neuron (Patch-seq) brings forward a unique opportunity to study the transcriptional correlates of functional properties and vice versa. Here, we provide a