Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Matthew S Gentry"'
Autor:
Michael Xiao, Chia-Hua Wu, Graham Meek, Brian Kelly, Dara Buendia Castillo, Lyndsay EA Young, Sara Martire, Sajina Dhungel, Elizabeth McCauley, Purbita Saha, Altair L Dube, Matthew S Gentry, Laura A Banaszynski, Ramon C Sun, Chintan K Kikani
Publikováno v:
eLife, Vol 12 (2023)
Quiescent stem cells are activated in response to a mechanical or chemical injury to their tissue niche. Activated cells rapidly generate a heterogeneous progenitor population that regenerates the damaged tissues. While the transcriptional cadence th
Externí odkaz:
https://doaj.org/article/697189baa2334a1aa47ad10289eafb8e
Autor:
Lyndsay E A Young, Lindsey R Conroy, Harrison A Clarke, Tara R Hawkinson, Kayli E Bolton, William C Sanders, Josephine E Chang, Madison B Webb, Warren J Alilain, Craig W Vander Kooi, Richard R Drake, Douglas A Andres, Tom C Badgett, Lars M Wagner, Derek B Allison, Ramon C Sun, Matthew S Gentry
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 11, Pp n/a-n/a (2022)
Abstract Glycogen dysregulation is a hallmark of aging, and aberrant glycogen drives metabolic reprogramming and pathogenesis in multiple diseases. However, glycogen heterogeneity in healthy and diseased tissues remains largely unknown. Herein, we de
Externí odkaz:
https://doaj.org/article/a448069261be43559f4205eb79956a31
Autor:
Michael D Schaller, Gary McDowell, André Porter, Dorothy Shippen, Katherine L Friedman, Matthew S Gentry, Tricia R Serio, Wesley I Sundquist
Publikováno v:
eLife, Vol 6 (2017)
Numerous concerns have been raised about the sustainability of the biomedical research enterprise in the United States. Improving the postdoctoral training experience is seen as a priority in addressing these concerns, but even identifying who the po
Externí odkaz:
https://doaj.org/article/4a22288ddf17473281626fa8a17bebaf
Autor:
Pablo Sánchez-Martín, Madushi Raththagala, Travis M Bridges, Satrio Husodo, Matthew S Gentry, Pascual Sanz, Carlos Romá-Mateo
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69523 (2013)
Laforin, encoded by a gene that is mutated in Lafora Disease (LD, OMIM 254780), is a modular protein composed of a carbohydrate-binding module and a dual-specificity phosphatase domain. Laforin is the founding member of the glucan-phosphatase family
Externí odkaz:
https://doaj.org/article/7122f49752f34a8eb9688f8e4986fdbc
Autor:
Vikas V Dukhande, Devin M Rogers, Carlos Romá-Mateo, Jordi Donderis, Alberto Marina, Adam O Taylor, Pascual Sanz, Matthew S Gentry
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24040 (2011)
Lafora Disease (LD) is a fatal neurodegenerative epileptic disorder that presents as a neurological deterioration with the accumulation of insoluble, intracellular, hyperphosphorylated carbohydrates called Lafora bodies (LBs). LD is caused by mutatio
Externí odkaz:
https://doaj.org/article/bdc9b1f38fd34510afa2b27da3cb1db0
Autor:
Federica Pondrelli, Raffaella Minardi, Lorenzo Muccioli, Corrado Zenesini, Luca Vignatelli, Laura Licchetta, Barbara Mostacci, Paolo Tinuper, Craig W. Vander Kooi, Matthew S. Gentry, Francesca Bisulli
Background: Lafora disease (LD) is a fatal form of progressive myoclonic epilepsy caused by biallelic pathogenic variants in EPM2A or NHLRC1. With a few exceptions, the influence of genetic factors on disease progression has yet to be confirmed. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b51965b78cac5342e7842c2827fd1d2d
https://doi.org/10.21203/rs.3.rs-2845960/v1
https://doi.org/10.21203/rs.3.rs-2845960/v1
Autor:
Lindsey R. Conroy, Harrison A. Clarke, Derek B. Allison, Samuel Santos Valenca, Qi Sun, Tara R. Hawkinson, Lyndsay E. A. Young, Juanita E. Ferreira, Autumn V. Hammonds, Jaclyn B. Dunne, Robert J. McDonald, Kimberly J. Absher, Brittany E. Dong, Ronald C. Bruntz, Kia H. Markussen, Jelena A. Juras, Warren J. Alilain, Jinze Liu, Matthew S. Gentry, Peggi M. Angel, Christopher M. Waters, Ramon C. Sun
Publikováno v:
Nature Communications. 14
Matrix assisted laser desorption/ionization imaging has greatly improved our understanding of spatial biology, however a robust bioinformatic pipeline for data analysis is lacking. Here, we demonstrate the application of high-dimensionality reduction
Autor:
Graham Meek, Chia-Hua Wu, Michael Xiao, Brian Kelly, Dara Buendia Castillo, Lyndsay EA Young, Sara Martire, Sajina Dhungel, Elizabeth McCauley, Purbita Saha, Altair L Dube, Matthew S Gentry, Laura A Banaszynski, Ramon C Sun, Chintan K Kikani
Publikováno v:
eLife. 12
Quiescent stem cells are activated in response to a mechanical or chemical injury to their tissue niche. Activated cells rapidly generate a heterogeneous progenitor population that regenerates the damaged tissues. While the transcriptional cadence th
Publikováno v:
Neurotherapeutics
Adult polyglucosan body disease (APBD) and Lafora disease (LD) are autosomal recessive glycogen storage neurological disorders. APBD is caused by mutations in the glycogen branching enzyme (GBE1) gene and is characterized by progressive upper and low
Autor:
Emily E Huffman, Brittany E Dong, Harrison A Clarke, Lyndsay E A Young, Matthew S Gentry, Derek B Allison, Ramon C Sun, Christopher M Waters, Warren J Alilain
Publikováno v:
Brain Communications. 5
High-cervical spinal cord injury often disrupts respiratory motor pathways and disables breathing in the affected population. Moreover, cervically injured individuals are at risk for developing acute lung injury, which predicts substantial mortality