Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Matthew R. Zanotelli"'
Autor:
Wenjun Wang, Matthew R. Zanotelli, Lindsey N. Sabo, Emily D. Fabiano, Natalie M. Goldfield, Chloe Le, Elle P. Techasiriwan, Santiago Lopez, Emily D. Berestesky, Cynthia A. Reinhart-King
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026120-026120-9 (2024)
Tumor vasculature plays a crucial role in tumor progression, affecting nutrition and oxygen transportation as well as the efficiency of drug delivery. While targeting pro-angiogenic growth factors has been a significant focus for treating tumor angio
Externí odkaz:
https://doaj.org/article/063ed9fe566747cc816bfb97adfc8a28
Autor:
Matthew R. Zanotelli, Aniqua Rahman-Zaman, Jacob A. VanderBurgh, Paul V. Taufalele, Aadhar Jain, David Erickson, Francois Bordeleau, Cynthia A. Reinhart-King
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Migrating cells tune their energy utilization in response to their microenvironment, but how cellular energetics direct navigation remains unclear. Here, the authors report that energetic costs for motility, regulated by cell mechanics and confinemen
Externí odkaz:
https://doaj.org/article/d89947d85d604810a3c24366f9f1743c
Autor:
Joseph P. Miller, Brandon H. Borde, Francois Bordeleau, Matthew R. Zanotelli, Danielle J. LaValley, Dylan J. Parker, Lawrence J. Bonassar, Susan C. Pannullo, Cynthia A. Reinhart-King
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031901-031901-11 (2018)
Cells receive mechanical cues from their extracellular matrix (ECM), which direct migration, differentiation, apoptosis, and in some cases, the transition to a cancerous phenotype. As a result, there has been significant research to develop methods t
Externí odkaz:
https://doaj.org/article/223ef4ec142d441abf2b1ed6d41a7e83
Autor:
Matthew R. Zanotelli, Aniqua Rahman-Zaman, Jacob A. VanderBurgh, Paul V. Taufalele, Aadhar Jain, David Erickson, Francois Bordeleau, Cynthia A. Reinhart-King
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/06b0615186df433ca7d9cb4f9f4ab60f
Autor:
Julia L. Jin, BS, Matthew R. Zanotelli, MS, Jaime L. Bernstein, BS, Yoshiko Toyoda, BA, Andrew I. Abadeer, Meng, Sarah J. Karinja, BA, Omer Kaymakcalan, MD, Peter A. Torzilli, PhD, Jason A. Spector, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 5, Iss 9S, Pp 111-112 (2017)
Externí odkaz:
https://doaj.org/article/8f2f051a376b4a99b62a17eab515cc43
Autor:
Oriana Y. Teran, Matthew R. Zanotelli, Miao-chong Joy Lin, Richard A. Cerione, Kristin F. Wilson
Cancer cells, both within a developing tumor and during metastatic spread, encounter many stresses that require adaptive mechanisms to survive and maintain malignant progression. Here we describe a signaling complex involving the small GTPase Cdc42 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::660736ab97cc7695fb1621f9244cd1a4
https://doi.org/10.1101/2023.01.03.522657
https://doi.org/10.1101/2023.01.03.522657
Publikováno v:
Cell Metab
Altered tissue mechanics and metabolism are defining characteristics of cancer that impact not only proliferation but also migration. While migrating through a mechanically and spatially heterogeneous microenvironment, changes in metabolism allow cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b2a91573ec6a8a89dd5647190846ad
https://doi.org/10.1016/j.cmet.2021.04.002
https://doi.org/10.1016/j.cmet.2021.04.002
Autor:
Matthew R. Zanotelli, Jian Zhang, Ismael Ortiz, Wenjun Wang, Neil C. Chada, Cynthia A. Reinhart-King
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(18)
Altered tissue mechanics and metabolism have gained significant attention as drivers of tumorigenesis, and mechanoresponsive metabolism has been implicated in migration and metastasis. However, heterogeneity in cell populations makes it difficult to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1da3d7eeacc26486a84f247d0b0909
https://pubmed.ncbi.nlm.nih.gov/35471912
https://pubmed.ncbi.nlm.nih.gov/35471912
Publikováno v:
Biophysical Reviews and Letters. 15:51-82
The tumor microenvironment plays a critical role in tumorigenesis and metastasis. As tightly controlled extracellular matrix homeostasis is lost during tumor progression, a dysregulated extracellular matrix can significantly alter cellular phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63c7ff209e9122df50857c6d297afb10
https://doi.org/10.1142/s1793048020300029
https://doi.org/10.1142/s1793048020300029
Autor:
Yoshiko Toyoda, Karel-Bart Celie, Xue Dong, Ryan Bender, Matthew R. Zanotelli, Julia L. Jin, Peipei Zhang, Rachel C. Hooper, Kerry A. Morrison, Jason A. Spector, Omer Kaymakcalan, Ope Asanbe
Publikováno v:
Acta Biomaterialia. 91:144-158
Introduction Insufficient vascularization of currently available clinical biomaterials has limited their application to optimal wound beds. We designed a hydrogel scaffold with a unique internal microstructure of differential collagen densities to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ac2926a3330b2b72daef369c1e8c90
https://doi.org/10.1016/j.actbio.2019.04.027
https://doi.org/10.1016/j.actbio.2019.04.027