Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Matthew R. Ramsey"'
Autor:
Julia Holzgruber, Christina Martins, Zsofi Kulcsar, Alexandra Duplaine, Erik Rasbach, Laure Migayron, Praveen Singh, Edith Statham, Jennifer Landsberg, Katia Boniface, Julien Seneschal, Wolfram Hoetzenecker, Emma L. Berdan, Shannan Ho Sui, Matthew R. Ramsey, Steven R. Barthel, Tobias Schatton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Programmed cell death 1 (PD-1) is a premier cancer drug target for immune checkpoint blockade (ICB). Because PD-1 receptor inhibition activates tumor-specific T-cell immunity, research has predominantly focused on T-cell-PD-1 expression and
Externí odkaz:
https://doaj.org/article/209ec2809d724247864f9587c7cce533
Autor:
Kotaro Sato, Kshitij Parag-Sharma, Masahiko Terajima, Adele M. Musicant, Ryan M. Murphy, Matthew R. Ramsey, Hideharu Hibi, Mitsuo Yamauchi, Antonio L. Amelio
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 6, Pp 594-606 (2021)
Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide and incidence rates are continuing to rise globally. HNSCC patient prognosis is closely related to the occurrence of tumor metastases, and collagen within the tumor
Externí odkaz:
https://doaj.org/article/d8f5418cce2442aeba6dabbe14e135a5
Autor:
Steven R. Barthel, Matthew R. Ramsey, Thomas S. Kupper, George F. Murphy, Christine G. Lian, Christoph Schlapbach, Jennifer Landsberg, Martin C. Mihm, Charles J. Dimitroff, Jennifer Liang, Anne Brandenburg, Kate Stewart, Jenna Geddes-Sweeney, Markus V. Heppt, Kyla Mucciarone, Mariana Silva, Praveen Singh, Erik Rasbach, Christina Martins, Yuta Itoh, Tobias Schatton
T-cell immunoglobulin mucin family member 3 (Tim-3) is an immune checkpoint receptor that dampens effector functions and causes terminal exhaustion of cytotoxic T cells. Tim-3 inhibitors are under investigation in immuno-oncology (IO) trials, because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::997588a1168fc6e4daee8e1fd7d501a6
https://doi.org/10.1158/0008-5472.c.6514280.v1
https://doi.org/10.1158/0008-5472.c.6514280.v1
Autor:
Steven R. Barthel, Matthew R. Ramsey, Thomas S. Kupper, George F. Murphy, Christine G. Lian, Christoph Schlapbach, Jennifer Landsberg, Martin C. Mihm, Charles J. Dimitroff, Jennifer Liang, Anne Brandenburg, Kate Stewart, Jenna Geddes-Sweeney, Markus V. Heppt, Kyla Mucciarone, Mariana Silva, Praveen Singh, Erik Rasbach, Christina Martins, Yuta Itoh, Tobias Schatton
Supplementary Data from Inhibition of Melanoma Cell–Intrinsic Tim-3 Stimulates MAPK-Dependent Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ae4e8e7422664ac2bb35f1c79054cf
https://doi.org/10.1158/0008-5472.22432958
https://doi.org/10.1158/0008-5472.22432958
Autor:
Norman E. Sharpless, Yue Xiong, Keith L. Ligon, Daniel R. Carrasco, Weili Lin, Chad Torrice, Xin-Hai Pei, Janakiraman Krishnamurthy, Matthew R. Ramsey
Supplementary Figures 1-2 from Expression of p16Ink4a Compensates for p18Ink4c Loss in Cyclin-Dependent Kinase 4/6–Dependent Tumors and Tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d09cc4da5541b24571c5d57f8d4f48e
https://doi.org/10.1158/0008-5472.22366829
https://doi.org/10.1158/0008-5472.22366829
Autor:
Norman E. Sharpless, Yue Xiong, Keith L. Ligon, Daniel R. Carrasco, Weili Lin, Chad Torrice, Xin-Hai Pei, Janakiraman Krishnamurthy, Matthew R. Ramsey
Cell cycle progression from G1 to S phase depends on phosphorylation of pRb by complexes containing a cyclin (D type or E type) and cyclin-dependent kinase (e.g., cdk2, cdk4, or cdk6). Ink4 proteins function to oppose the action of cdk4/6-cyclin D co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7204c9e1282fce8aa2ad1e9e9b036424
https://doi.org/10.1158/0008-5472.c.6495311.v1
https://doi.org/10.1158/0008-5472.c.6495311.v1
Supplementary Figures 1-4, Table 1, Methods from Physical Association of HDAC1 and HDAC2 with p63 Mediates Transcriptional Repression and Tumor Maintenance in Squamous Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f02fec8764755a75a41d7ab9d7c5ce
https://doi.org/10.1158/0008-5472.22389168
https://doi.org/10.1158/0008-5472.22389168
Autor:
Rafik Boudra, Bethany L. Patenall, Sandra King, Diana Wang, Sarah A. Best, Joo Yeon Ko, Shuyun Xu, Maria G. Padilla, Chrysalyne D. Schmults, Steven R. Barthel, Christine G. Lian, Matthew R. Ramsey
Publikováno v:
bioRxiv
SummarySquamous Cell Carcinoma (SCC) develops in stratified epithelial tissues and demonstrates frequent alterations in transcriptional regulators. We sought to discover SCC-specific transcriptional programs and identified the transcription factor Ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0441be16980c740d3ca9304c9df815d
https://europepmc.org/articles/PMC10081292/
https://europepmc.org/articles/PMC10081292/
Autor:
Hideharu Hibi, Mitsuo Yamauchi, Masahiko Terajima, Antonio L. Amelio, Kshitij Parag-Sharma, Adele M. Musicant, Ryan M. Murphy, Matthew R. Ramsey, Kotaro Sato
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 6, Pp 594-606 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 6, Pp 594-606 (2021)
Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide and incidence rates are continuing to rise globally. HNSCC patient prognosis is closely related to the occurrence of tumor metastases, and collagen within the tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7683064dfa14d0bc66905c537286b0f
https://doi.org/10.1016/j.neo.2021.05.014
https://doi.org/10.1016/j.neo.2021.05.014
Publikováno v:
Journal of Investigative Dermatology. 137:506-512
CCAR2 is a widely expressed protein involved in the regulation of a variety of transcriptional complexes. High expression of CCAR2 correlates with poor outcomes in a variety of human tumor types such as Squamous Cell Carcinoma (SCC). Paradoxically, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ba71ace391679be605d825f6ea90a5
https://doi.org/10.1016/j.jid.2016.09.027
https://doi.org/10.1016/j.jid.2016.09.027