Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Matthew R. Nussio"'
Autor:
Kathleen M. Knights, Peter I. Mackenzie, Joseph G. Shapter, Matthew R. Nussio, David Hallifax, John O. Miners, Andrew Rowland, J. Brian Houston
Publikováno v:
Xenobiotica. 45:847-857
1. This study compared the extent, affinity, and kinetics of drug binding to human serum albumin (HSA) and liver fatty acid binding protein (LFABP) using ultrafiltration and surface plasmon resonance (SPR). 2. Binding of basic and neutral drugs to bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423c5d46e4277e8985803f3c8b043ac3
https://doi.org/10.3109/00498254.2015.1021403
https://doi.org/10.3109/00498254.2015.1021403
Publikováno v:
Biophysical Journal. 99:834-844
The effect of cholesterol (CHOL) on the material properties of supported lipid bilayers composed of lipid mixtures that mimic the composition of lipid microdomains was studied by force-volume (FV) imaging under near-physiological conditions. These st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d709b4ccbf7acc6eebc26d6537daa6c
https://doi.org/10.1016/j.bpj.2010.04.072
https://doi.org/10.1016/j.bpj.2010.04.072
Autor:
Fausto Sanz, Matthew R. Nussio, Joseph G. Shapter, Nicolas H. Voelcker, Gerard Oncins, Endre J. Szili, Ingrid Ridelis
Publikováno v:
The Journal of Physical Chemistry B. 113:10339-10347
In this study, we compare for the first time the nanomechanical properties of lipid bilayer islands on flat and porous surfaces. 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC) and 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) bilay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a060d8787c2122800aa0361516b344
https://doi.org/10.1021/jp811035g
https://doi.org/10.1021/jp811035g
Publikováno v:
Journal of Nanoparticle Research. 11:2013-2022
The adhesion of gold nanoparticles either electrostatically or chemically attached to a substrate has been probed using AFM operating in force spectroscopy mode. A monolayer of –NH2 terminated 3-aminopropyltriethoxysilane or –SH terminated 3-merc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddae2aacf8d7e3840955819a10168b56
https://doi.org/10.1007/s11051-008-9562-1
https://doi.org/10.1007/s11051-008-9562-1
Publikováno v:
Langmuir. 24:4238-4244
Expanded cross-linked copolymers of poly(N-isopropylacrylamide) (PNiPAAm) and poly(acrylic acid) (PAAc) of varying monomer ratios were grafted from a crystalline silicon surface. Surface-tethered polymerization was performed at a slightly basic pH, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a906c330905551487282517c0305d9f4
https://doi.org/10.1021/la703668s
https://doi.org/10.1021/la703668s
Autor:
Matthew R. Nussio, Monessha Nambiar, Susanne Zeile, Bandaru Narasimha Murthy, Christopher T. Gibson, Joseph G. Shapter, Nicolas H. Voelcker, Narayanaswamy Jayaraman
Solubilization of single walled carbon nanotubes (SWNTs) in aqueous milieu by self assembly of bivalent glycolipids is described. Thorough analysis of the resulting composites involving Vis/near-IR spectroscopy, surface plasmon resonance, confocal Ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac8089eb7c9a09041f8579e7b45894a
https://hdl.handle.net/1959.8/154873
https://hdl.handle.net/1959.8/154873
Autor:
Juliet A. Gerrard, Stefani S. Griesser, Heath Ecroyd, Sofia Giorgetti, Benjamin Thierry, Matthew R. Nussio, Vittorio Bellotti, Joseph G. Shapter, Hans J. Griesser, Megan Garvey, John A. Carver
Publikováno v:
Biopolymers. 95(6)
The well-characterized small heat-shock protein, alphaB-crystallin, acts as a molecular chaperone by interacting with unfolding proteins to prevent their aggregation and precipitation. Structural perturbation (e.g., partial unfolding) enhances the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d0629c5e0cd4061187b80520fd87b8
https://pubmed.ncbi.nlm.nih.gov/21225714
https://pubmed.ncbi.nlm.nih.gov/21225714
Autor:
Nicolas H. Voelcker, Matthew J. Sykes, Joseph G. Shapter, John O. Miners, Matthew R. Nussio, Benjamin C. Lewis
Publikováno v:
Chemistry and physics of lipids. 163(2)
Cytochromes P450 (CYP) are key enzymes involved in the metabolism of drugs and other lipophilic xenobiotics and endogenous compounds. In this study, atomic force microscopy was applied to characterise the association of CYP2C9 to dimyristoylphosphati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edc06ec4224877364f9698b588a6c92
https://pubmed.ncbi.nlm.nih.gov/19925783
https://pubmed.ncbi.nlm.nih.gov/19925783
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 25(2)
Drug-membrane interactions assume considerable importance in pharmacokinetics and drug metabolism. Here, we present the interaction of chlorpromazine hydrochloride (CPZ) with supported phospholipid bilayers. It was demonstrated that CPZ binds rapidly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf2bad2b8f17a18ec3090962b431759
https://pubmed.ncbi.nlm.nih.gov/19093750
https://pubmed.ncbi.nlm.nih.gov/19093750
Autor:
John O. Miners, Matthew J. Sykes, Nicolas H. Voelcker, Matthew R. Nussio, Benjamin S. Flavel, Joseph G. Shapter
Publikováno v:
ResearcherID
The analysis of membrane domain segregation and phase separation is of significant interest for the understanding of cell membranes. In this paper, we report a new approach to atomic force microscopy (AFM) of artificial membranes, using both function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecda882a43a215b56a6ef907e2120e0
https://doi.org/10.1109/iconn.2008.4639261
https://doi.org/10.1109/iconn.2008.4639261