Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Matthew R. Medcalf"'
Publikováno v:
Metabolites, Vol 12, Iss 1, p 24 (2021)
Methotrexate (MTX) is widely used in the treatment of autoimmune arthritis but is limited by its unpredictable and variable response profile. Currently, no biomarkers exist to predict or monitor early therapeutic responses to MTX. Using a collagen-in
Externí odkaz:
https://doaj.org/article/ddc0a2caa5054cf7ae67f9f52aa01b96
Autor:
Matthew R. Medcalf, Pooja Bhadbhade, Ted R. Mikuls, James R. O’Dell, Rebekah L. Gundry, Ryan S. Funk
Publikováno v:
Metabolites, Vol 11, Iss 12, p 824 (2021)
Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response
Externí odkaz:
https://doaj.org/article/a65b59be9dd14d04a4415b95ee3d7621
Autor:
Kevin D. Moeller, Kendall J. Blumer, Matthew R. Medcalf, Ruby L. Krueger, Zach T. Medcalf, Peter A. Rosston, Yu Zhu, Kevin M. Kaltenbronn
Publikováno v:
Synthesis (Stuttg)
The biological activity of natural products YM-254890 (YM) and FR900359 (FR) has led to significant interest in both their synthesis and the construction of more simplified analogs. While the simplified analogs lose much of the potency of the natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e32974a43d907392f34d8b43ec92d47
https://europepmc.org/articles/PMC9838186/
https://europepmc.org/articles/PMC9838186/
Autor:
Matthew R. Medcalf, Leonidas E. Bantis, Peng Shi, Pooja Bhadbhade, Rebekah L. Gundry, Ted R. Mikuls, Bryant R. England, James R. O'Dell, Ryan S. Funk
Publikováno v:
SSRN Electronic Journal.
Methotrexate (MTX) remains the first-choice disease-modifying therapy in rheumatoid arthritis (RA). However, clinical response is variable, and no reliable predictive biomarkers of efficacy currently exist. In this study, plasma metabolomic profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d5a9477ff190ad9d7da942ecf3ea37
https://doi.org/10.2139/ssrn.4084764
https://doi.org/10.2139/ssrn.4084764
Autor:
Matthew R. Medcalf, Clark B. Summers, Jamie A. Veliz, Eric B. Hines, Katherine E. Hundley, Ryan R. Parmar, Lakshmi N. Roy, Rabindra N. Roy, Lucas S. Tebbe, John J. Dinga
Publikováno v:
Journal of Biophysical Chemistry. :91-98
Values of the second thermodynamic dissociation constant pK2 of the protonated form of monosodium 1,4-piperazinediethanesulfonate (PIPES) have been determined at twelve different temperatures in the temperature range from (278.15 to 328.15) K includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a6a2810881b36071abd1a425e97fb5
https://doi.org/10.4236/jbpc.2014.53010
https://doi.org/10.4236/jbpc.2014.53010