Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Matthew R. Lewin"'
Publikováno v:
Toxins, Vol 15, Iss 10, p 598 (2023)
A field biologist was bitten by a female Nikolsky’s viper (Vipera berus nikolskii) in Kharkiv Oblast, Ukraine. Two months later, the patient began to experience cold-induced vasospasm of the affected digit diagnosed as acquired Raynaud phenomenon.
Externí odkaz:
https://doaj.org/article/343c207d51cf43bab1cb2095b7cded42
Autor:
Lyndi L. Gilliam, John Gilliam, Stephen P. Samuel, Rebecca W. Carter, Jerry Ritchey, Tommaso Bulfone, José María Gutiérrez, David J. Williams, Daniela M. Durkin, Sally I. Stephens, Matthew R. Lewin
Publikováno v:
Toxins, Vol 15, Iss 9, p 557 (2023)
Antivenom is currently the standard-of-care treatment for snakebite envenoming, but its efficacy is limited by treatment delays, availability, and in many cases, species specificity. Many of the rapidly lethal effects of envenoming are caused by veno
Externí odkaz:
https://doaj.org/article/1006e9abf5ee4345884a8bfb0b1bc445
Publikováno v:
Toxins, Vol 15, Iss 1, p 49 (2023)
Respiratory and airway-protective muscle weakness caused by the blockade of neuromuscular transmission is a major cause of early mortality from snakebite envenoming (SBE). Once weakness is manifest, antivenom appears to be of limited effectiveness in
Externí odkaz:
https://doaj.org/article/14b5c3e097494964a949cad50d5302aa
Autor:
Abhinandan Chowdhury, Matthew R. Lewin, Rebecca Carter, Raul Soria, Matt Aldridge, Bryan G. Fry
Publikováno v:
Toxins, Vol 14, Iss 12, p 836 (2022)
The African viperid snake genera Atheris, Cerastes, and Proatheris are closely related, similar in size, but occupy extremely divergent ecological niches (arboreal in tropical rainforests, fossorial in deserts, and swamp-dwelling, respectively). Thei
Externí odkaz:
https://doaj.org/article/ab238764fab64504a8027d72c2b36d8c
Autor:
Rebecca W. Carter, Charles J. Gerardo, Stephen P. Samuel, Surendra Kumar, Suneetha D. Kotehal, Partha P. Mukherjee, Farshad M. Shirazi, Peter D. Akpunonu, Chanaveerappa Bammigatti, Ashish Bhalla, Neeraj Manikath, Timothy F. Platts-Mills, Matthew R. Lewin
Publikováno v:
Toxins, Vol 15, Iss 1, p 22 (2022)
Introduction: Snakebite is an urgent, unmet global medical need causing significant morbidity and mortality worldwide. Varespladib is a potent inhibitor of venom secretory phospholipase A2 (sPLA2) that can be administered orally via its prodrug, vare
Externí odkaz:
https://doaj.org/article/c311204965e24b16a3d9d91af6d28086
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
African spitting cobras are unique among cobras for their potent anticoagulant venom activity arising from strong inhibition of Factor Xa. This anticoagulant effect is exerted by venom phospholipase A2 (Group I PLA2) toxins whose activity contributes
Externí odkaz:
https://doaj.org/article/6c5b8a7158544a4584538ca992da9c1e
Autor:
Muhammad Hamza, Cecilie Knudsen, Christeine Ariaranee Gnanathasan, Wuelton Monteiro, Matthew R. Lewin, Andreas H. Laustsen, Abdulrazaq G. Habib
Publikováno v:
Toxicon: X, Vol 11, Iss , Pp 100079- (2021)
Snakebite envenoming is a major cause of morbidity and mortality in rural communities throughout the tropics. Generally, the main clinical features of snakebites are local swelling, tissue necrosis, shock, spontaneous systemic hemorrhage, incoagulabl
Externí odkaz:
https://doaj.org/article/e2ea5e9d82f84b21a9e430ffa6c9c08d
Autor:
Matthew R. Lewin, Rebecca W. Carter, Isabel A. Matteo, Stephen P. Samuel, Sunita Rao, Bryan G. Fry, Philip E. Bickler
Publikováno v:
Toxins, Vol 14, Iss 11, p 783 (2022)
The availability of effective, reliably accessible, and affordable treatments for snakebite envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin-specific inhibitors with oral bioavailability used in conjunction with
Externí odkaz:
https://doaj.org/article/f40412e125cf47e3a31c4b6c8f7dda5e
Autor:
Abhinandan Chowdhury, Christina N. Zdenek, Matthew R. Lewin, Rebecca Carter, Tomaž Jagar, Erika Ostanek, Hannah Harjen, Matt Aldridge, Raul Soria, Grace Haw, Bryan G. Fry
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Palearctic vipers are medically significant snakes in the genera Daboia, Macrovipera, Montivipera, and Vipera which occur throughout Europe, Central Asia, Near and Middle East. While the ancestral condition is that of a small-bodied, lowland species,
Externí odkaz:
https://doaj.org/article/c4093c89a64943138728be0ff61fcf2e
Autor:
Daniela M. Durkin, Alison N. Young, Kent Khtikian, Zuzana Karjala, Arin L. Isenstein, Bryan G. Fry, Matthew R. Lewin
Publikováno v:
Toxins, Vol 14, Iss 7, p 495 (2022)
Bites from venomous marine annelid ‘bloodworms’ (e.g., Glycera spp.) do not appear to have been described in the medical literature despite being seemingly well-known to bait diggers and fishermen. The few laboratory study reports describe their
Externí odkaz:
https://doaj.org/article/f1db19328e424dd09eaf8f96f32d0d01