Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthew R. Hendricks"'
Autor:
Grace P. Carreno-Florez, Brian R. Kocak, Matthew R. Hendricks, Jeffrey A. Melvin, Katrina B. Mar, Jessica Kosanovich, Rachel L. Cumberland, Greg M. Delgoffe, Sruti Shiva, Kerry M. Empey, John W. Schoggins, Jennifer M. Bomberger
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/27a20c8a04344fb7b4939fe6ea404259
Autor:
Allison L. Haas, Anna C. Zemke, Jeffrey A. Melvin, Catherine R. Armbruster, Matthew R. Hendricks, John Moore, Seyed Mehdi Nouraie, Patrick H. Thibodeau, Stella E. Lee, Jennifer M. Bomberger
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112270- (2023)
Summary: The cystic fibrosis (CF) respiratory tract harbors pathogenic bacteria that cause life-threatening chronic infections. Of these, Pseudomonas aeruginosa becomes increasingly dominant with age and is associated with worsening lung function and
Externí odkaz:
https://doaj.org/article/d50ebee9b83744a1b83baf06756823ac
Autor:
Lily A. Charpentier, Emily F. Dolben, Matthew R. Hendricks, Deborah A. Hogan, Jennifer M. Bomberger, Bruce A. Stanton
Publikováno v:
Membranes, Vol 13, Iss 9, p 752 (2023)
This article reviews the role of outer membrane vesicles (OMVs) in mediating the interaction between Gram-negative bacteria and their human hosts. OMVs are produced by a diverse range of Gram-negative bacteria during infection and play a critical rol
Externí odkaz:
https://doaj.org/article/e67c0166bb3e4493b2ba355ab0705a8c
Publikováno v:
mSphere, Vol 2, Iss 4 (2017)
ABSTRACT Clostridium perfringens enterotoxin (CPE) causes the diarrhea associated with a common bacterial food poisoning and many antibiotic-associated diarrhea cases. The severity of some CPE-mediated disease cases warrants the development of potent
Externí odkaz:
https://doaj.org/article/df344bf88aff4a9fb873e37a31048e96
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT Clostridium perfringens enterotoxin (CPE) binds to claudin receptors, e.g., claudin-4, and then forms a pore that triggers cell death. Pure cultures of host cells that do not express claudin receptors, e.g., fibroblasts, are unaffected by pa
Externí odkaz:
https://doaj.org/article/de0a0e4ae92f4adba6bf1dd16c8066e2
Autor:
Matthew R. Hendricks, Ram Savan
Publikováno v:
Science (New York, N.y.)
Immunity
Immunity
Summary Type I and III interferons (IFNs) drive effective antiviral functions but differentially affect tissue homeostasis. Using mouse models of severe inflammation, Broggi et al. and Major et al. report in Science that type III IFNs disrupt epithel
Autor:
Jennifer M. Bomberger, Yingshi Ouyang, Yoel Sadovsky, Donna B. Stolz, John V. Williams, Jeffrey A. Melvin, Sidney Lane, Matthew R. Hendricks
Publikováno v:
Cell reports
SUMMARY Extracellular vesicles (EVs) are increasingly appreciated as a mechanism of communication among cells that contribute to many physiological processes. Although EVs can promote either antiviral or proviral effects during viral infections, the
Autor:
Lucas Brane, Jay K. Kolls, Jonathan P. Richardson, Matthew R. Hendricks, Amy G. Hise, J. Agustin Cruz, Erin E. Childs, Sean C. Daugherty, Scott G. Filler, Norma V. Solis, Bianca M. Coleman, Joseph P. Hunter, Bemnet G. Mengesha, Abhishek V. Garg, Danielle La Saevig, Akash H. Verma, Heather R. Conti, Vincent M. Bruno, Satrajit Sinha, Sarah L. Gaffen, Julian R. Naglik
Publikováno v:
Conti, HR, Bruno, VM, Childs, EE, Daugherty, S, Hunter, JP, Mengesha, BG, Saevig, DL, Hendricks, MR, Coleman, BM, Brane, L, Solis, N, Cruz, J A, Verma, AH, Garg, AV, Hise, AG, Richardson, J P, Naglik, J R, Filler, SG, Kolls, JK, Sinha, S & Gaffen, SL 2016, ' IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis ', Cell Host & Microbe, vol. 20, no. 5, pp. 606–617 . https://doi.org/10.1016/j.chom.2016.10.001
Summary Signaling through the IL-17 receptor (IL-17R) is required to prevent oropharyngeal candidiasis (OPC) in mice and humans. However, the IL-17-responsive cell type(s) that mediate protection are unknown. Using radiation chimeras, we were able to
Publikováno v:
Journal of Virology. 90:4258-4261
Respiratory virus infections are common but generally self-limiting infections in healthy individuals. Although early clinical studies reported low detection rates, the development of molecular diagnostic techniques by PCR has led to an increased rec
Autor:
Chia Heng Lee, Emily A. Hemann, Marija S. Nadjsombati, Stephen K. Anderson, Richard Green, Snehal Ozarkar, Chandra Nath Roy, Saumendra N. Sarkar, Michael Gale, Ram Savan, Lomon So, Matthew R. Hendricks, Jakob von Moltke, Hongchuan Li, Adriana Forero
Publikováno v:
Immunity. 51(3)
Summary Type I and III interferons (IFNs) activate similar downstream signaling cascades, but unlike type I IFNs, type III IFNs (IFNλ) do not elicit strong inflammatory responses in vivo. Here, we examined the molecular mechanisms underlying this di