Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Matthew R Scott"'
Autor:
Shiraz Vered, Alexa S. Beiser, Liron Sulimani, Sharon Sznitman, Mitzi M. Gonzales, Hugo J. Aparicio, Charles DeCarli, Matthew R. Scott, Saptaparni Ghosh, Gil M. Lewitus, David Meiri, Sudha Seshadri, Galit Weinstein
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Preclinical studies highlight the importance of endogenous cannabinoids (endocannabinoids; eCBs) in neurodegeneration. Yet, prior observational studies focused on limited outcome measures and assessed only few eCB compounds while
Externí odkaz:
https://doaj.org/article/093f68cbea874b4aa79ffe745a7b724d
Autor:
Prokopis C. Prokopiou, Nina Engels-Domínguez, Kathryn V. Papp, Matthew R. Scott, Aaron P. Schultz, Christoph Schneider, Michelle E. Farrell, Rachel F. Buckley, Yakeel T. Quiroz, Georges El Fakhri, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I. L. Jacobs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Older individuals exhibiting diminished function of the locus coeruleus while learning new information show faster cognitive decline that is typical for Alzheimer’s disease.
Externí odkaz:
https://doaj.org/article/064e0e4a05864dea8910777843fb04ad
Autor:
Xiaojun Hu, Weijian Luo, Jiliang Hu, Sheng Guo, Weilin Huang, Matthew R. Scott, Roland Wiest, Michael Dahlweid, Mauricio Reyes
Publikováno v:
BMC Medical Imaging, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract MR images (MRIs) accurate segmentation of brain lesions is important for improving cancer diagnosis, surgical planning, and prediction of outcome. However, manual and accurate segmentation of brain lesions from 3D MRIs is highly expensive, t
Externí odkaz:
https://doaj.org/article/f1619771d581480a841fa37719ba0091
Autor:
Matthew R. Scott, Olivia L. Hampton, Rachel F. Buckley, Jasmeer P. Chhatwal, Bernard J. Hanseeuw, Heidi IL. Jacobs, Michael J. Properzi, Justin S. Sanchez, Keith A. Johnson, Reisa A. Sperling, Aaron P. Schultz
Publikováno v:
NeuroImage, Vol 220, Iss , Pp 116991- (2020)
Neurofibrillary tau tangles are a hallmark pathology of Alzheimer's disease (AD) and are more closely associated with AD-related cortical atrophy and symptom severity than amyloid-beta (Aβ). However, studies regarding the effect of tau on longitudin
Externí odkaz:
https://doaj.org/article/e277ebee1046491c8973965075c1da79
Autor:
Olivia L. Hampton, Rachel F. Buckley, Lyssa K. Manning, Matthew R. Scott, Michael J. Properzi, Cleofé Peña-Gómez, Heidi I.L. Jacobs, Jasmeer P. Chhatwal, Keith A. Johnson, Reisa A. Sperling, Aaron P. Schultz
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102407- (2020)
Proteinopathies are key elements in the pathogenesis of age-related neurodegenerative diseases, particularly Alzheimer’s disease (AD), with the nature and location of the proteinopathy characterizing much of the disease phenotype. Susceptibility of
Externí odkaz:
https://doaj.org/article/9dd0e669cf9846008e81c5c15a1e2ed6
Autor:
Aaron P Schultz, Rachel F Buckley, Olivia L Hampton, Matthew R Scott, Michael J Properzi, Cleofé Peña-Gómez, Jeremy J Pruzin, Hyun-Sik Yang, Keith A Johnson, Reisa A Sperling, Jasmeer P Chhatwal
Publikováno v:
NeuroImage: Clinical, Vol 26, Iss , Pp - (2020)
Resting-state functional connectivity MRI (rs-fcMRI) is a non-invasive imaging technique that has come into increasing use to understand disrupted neural network function in neuropsychiatric disease. However, despite extensive study over the past 15
Externí odkaz:
https://doaj.org/article/6b859cf3219b4577b6a4e5af02bfe0a2
Autor:
Emma Nichols, Richard Merrick, Simon I Hay, Dibya Himali, Jayandra J Himali, Sally Hunter, Hannah A D Keage, Caitlin S Latimer, Matthew R Scott, Jaimie D Steinmetz, Jamie M Walker, Stephen B Wharton, Crystal D Wiedner, Paul K Crane, C Dirk Keene, Lenore J Launer, Fiona E Matthews, Julie Schneider, Sudha Seshadri, Lon White, Carol Brayne, Theo Vos
Refereed/Peer-reviewed Background: Population-based autopsy studies provide valuable insights into the causes of dementia but are limited by sample size and restriction to specific populations. Harmonisation across studies increases statistical power
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a18d5c62b55cf0622555f702f64c61
https://hdl.handle.net/11541.2/33489
https://hdl.handle.net/11541.2/33489
Autor:
Emer R McGrath, Matthew R Scott, Rachel Buckley, Claudia L Satizabal, Charles S. DeCarli, Shalender Bhasin, Ramachandran S Vasan, Joanne M Murabito, Alexa S Beiser, Sudha Seshadri
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Prokopis C. Prokopiou, Nina Engels-Domínguez, Kathryn V. Papp, Matthew R. Scott, Aaron P. Schultz, Christoph Schneider, Michelle E. Farrell, Rachel F. Buckley, Yakeel T. Quiroz, Georges El Fakhri, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I. L. Jacobs
Publikováno v:
Nature Communications, 13(1):1571. Nature Publishing Group
Animal and human imaging research reported that the presence of cortical Alzheimer's Disease's (AD) neuropathology, beta-amyloid and neurofibrillary tau, is associated with altered neuronal activity and circuitry failure, together facilitating clinic
Publikováno v:
IEEE Transactions on Image Processing. 29:8187-8198
The ability to synthesize multi-modality data is highly desirable for many computer-aided medical applications, e.g. clinical diagnosis and neuroscience research, since rich imaging cohorts offer diverse and complementary information unraveling human