Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Matthew R Aronson"'
Publikováno v:
APL Bioengineering, Vol 5, Iss 1, Pp 011501-011501-11 (2021)
Most clinically approved cancer therapies are potent and toxic small molecules that are limited by severe off-target toxicities and poor tumor-specific localization. Over the past few decades, attempts have been made to load chemotherapies into lipos
Externí odkaz:
https://doaj.org/article/b952dad308de4afb83b36f5cc521b811
Autor:
Atip Lawanprasert, Caitlin A Guinan, Erica A Langford, Carly E Hawkins, Janna N Sloand, Howard W Fescemyer, Matthew R Aronson, Jacob A Halle, James H Marden, Scott H Medina
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229467 (2020)
Glycans are multi-branched sugars that are displayed from lipids and proteins. Through their diverse polysaccharide structures they can potentiate a myriad of cellular signaling pathways involved in development, growth, immuno-communication and survi
Externí odkaz:
https://doaj.org/article/f852500316364d2589b72844cafb4cc4
Publikováno v:
Molecules, Vol 25, Iss 12, p 2751 (2020)
Antimicrobial discovery in the age of antibiotic resistance has demanded the prioritization of non-conventional therapies that act on new targets or employ novel mechanisms. Among these, supramolecular antimicrobial peptide assemblies have emerged as
Externí odkaz:
https://doaj.org/article/d7a221707c4c42ec96d6ddbc07b5dd6e
Autor:
Paul M. Gehret, Ian N. Jacobs, Riccardo Gottardi, Matthew R. Aronson, Soheila Ali Akbari Ghavimi
Publikováno v:
The Laryngoscope. 132:1356-1363
OBJECTIVES/HYPOTHESIS Subglottic stenosis (SGS) results from dysregulated extracellular matrix deposition by laryngotracheal fibroblasts causing scar tissue formation following intubation. Recent work has highlighted a relationship between this infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8db1c33012f48ceeefb81e096966a5b
https://doi.org/10.1002/lary.29769
https://doi.org/10.1002/lary.29769
Autor:
Paul M. Gehret, Ryan C. Borek, John A. Germiller, Soheila Ali Akbari Ghavimi, Matthew R. Aronson, Riccardo Gottardi, Ian N. Jacobs, Karen B. Zur, Kyra W.Y. Smith, Rossana Schipani
Publikováno v:
Advanced Drug Delivery Reviews. 174:168-189
Pediatric upper airway disorders are frequently life-threatening and require precise assessment and intervention. Targeting these pathologies remains a challenge for clinicians due to the high complexity of pediatric upper airway anatomy and numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddbe60b4188759405e8bac3f1173375
https://doi.org/10.1016/j.addr.2021.04.004
https://doi.org/10.1016/j.addr.2021.04.004
Autor:
Christy George, John N. Alumasa, Adam Bolotsky, Michael D. Howe, Anthony D. Baughn, Dennis C. Chan, Andrew W. Simonson, Scott H. Medina, Elizabeth A. Proctor, Tapas K. Mal, Kenneth C. Keiler, Agustey S. Mongia, Atip Lawanprasert, Matthew R. Aronson, Aida Ebrahimi
Publikováno v:
Nature biomedical engineering
Precision antimicrobials aim to kill pathogens without damaging commensal bacteria in the host, and thereby cure disease without antibiotic-associated dysbiosis. Here we report the de novo design of a synthetic host defence peptide that targets a spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ca644ed7043ad5af37917b7eeef625
http://europepmc.org/articles/PMC8131206
http://europepmc.org/articles/PMC8131206
Autor:
Katherine M. Aird, Matthew R. Aronson, Jacob A. Halle, Rose A. Gogal, Andrew W. Simonson, Scott H. Medina, Adam B. Glick, Erika S. Dahl
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Bacteria and cancer cells share a common trait—both possess an electronegative surface that distinguishes them from healthy mammalian counterparts. This opens opportunities to repurpose antimicrobial peptides (AMPs), which are cationi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1d0253160446bb128f8dd700fa165d
https://europepmc.org/articles/PMC7596148/
https://europepmc.org/articles/PMC7596148/
Autor:
Elizabeth A. Proctor, Agustey S. Mongia, Kenneth C. Keiler, Andrew W. Simonson, Dennis C. Chan, Aida Ebrahimi, Matthew R. Aronson, John N. Alumasa, Adam Bolotsky, Scott H. Medina
Precision antimicrobials that can kill pathogens without damaging host commensals hold potential to cure disease without antibiotic-associated dysbiosis. Here we report the de novo design of host defense peptides that have been rationally engineered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9764a2c27e9275a2abfacb11be4153
https://doi.org/10.26434/chemrxiv.12267992
https://doi.org/10.26434/chemrxiv.12267992
Autor:
Christina Go, Yi Zhang, Taha Cangoz, Jonathan Soboloff, Robert Hooper, Muniswamy Madesh, Bryant Schultz, Neeharika Nemani, Matthew R. Aronson
Publikováno v:
Science Signaling. 12
Ca2+ signals, which facilitate pluripotent changes in cell fate, reflect the balance between cation entry and export. We found that overexpression of either isoform of the Ca2+-extruding plasma membrane calcium ATPase 4 (PMCA4) pump in Jurkat T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bf4056cb933f1589b5d7863d155b7b
https://doi.org/10.1126/scisignal.aaw2627
https://doi.org/10.1126/scisignal.aaw2627
Publikováno v:
APL Bioengineering, Vol 5, Iss 1, Pp 011501-011501-11 (2021)
APL Bioengineering
APL Bioengineering
Most clinically approved cancer therapies are potent and toxic small molecules that are limited by severe off-target toxicities and poor tumor-specific localization. Over the past few decades, attempts have been made to load chemotherapies into lipos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1174a1d3cc4404688edf577e24dfe6
https://doaj.org/article/b952dad308de4afb83b36f5cc521b811
https://doaj.org/article/b952dad308de4afb83b36f5cc521b811