Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Matthew R Allen"'
Autor:
John G Damrath, Neal X Chen, Corinne E Metzger, Shruthi Srinivasan, Kalisha O'Neill, Annabel Biruete, Keith G Avin, Joseph M Wallace, Matthew R Allen, Sharon M Moe
Publikováno v:
JBMR Plus, Vol 6, Iss 3, Pp n/a-n/a (2022)
ABSTRACT Chronic kidney disease‐mineral and bone disorder (CKD‐MBD) increases cardiovascular calcification and skeletal fragility in part by increasing systemic oxidative stress and disrupting mineral homeostasis through secondary hyperparathyroi
Externí odkaz:
https://doaj.org/article/84eb20bab12e481584fe0301a35fc26d
Autor:
Rachel Kohler, Carli A Tastad, Alexander J Stacy, Elizabeth A Swallow, Corinne E Metzger, Matthew R Allen, Joseph M Wallace
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
ABSTRACT Micro‐computed tomography is a critical assessment tool for bone‐related preclinical research, especially in murine models. To expedite the scanning process, researchers often image multiple bones simultaneously; however, it is unknown i
Externí odkaz:
https://doaj.org/article/11c385f7d9b44f979b7c60cafb1e4807
Autor:
Gregory G Grecco, Briana E Mork, Jui-Yen Huang, Corinne E Metzger, David L Haggerty, Kaitlin C Reeves, Yong Gao, Hunter Hoffman, Simon N Katner, Andrea R Masters, Cameron W Morris, Erin A Newell, Eric A Engleman, Anthony J Baucum, Jiuen Kim, Bryan K Yamamoto, Matthew R Allen, Yu-Chien Wu, Hui-Chen Lu, Patrick L Sheets, Brady K Atwood
Publikováno v:
eLife, Vol 10 (2021)
Despite the rising prevalence of methadone treatment in pregnant women with opioid use disorder, the effects of methadone on neurobehavioral development remain unclear. We developed a translational mouse model of prenatal methadone exposure (PME) tha
Externí odkaz:
https://doaj.org/article/5a76cf5be8ef4e9aa4a2a863c7ea3745
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250438 (2021)
Chronic kidney disease (CKD) causes bone loss, particularly in cortical bone, through formation of cortical pores which lead to skeletal fragility. Animal models of CKD have shown variability in the skeletal response to CKD between males and females
Externí odkaz:
https://doaj.org/article/fd497ebbaea44f74a62727f54a5e7638
Autor:
Matthew R Allen, Joseph Wallace, Erin McNerney, Jeffry Nyman, Keith Avin, Neal Chen, Sharon Moe
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230379 (2020)
Individuals with chronic kidney disease have elevated levels of oxidative stress and are at a significantly higher risk of skeletal fracture. Advanced glycation end products (AGEs), which accumulate in bone and compromise mechanical properties, are k
Externí odkaz:
https://doaj.org/article/1546b9e8414a419d8a317e1340ce093b
Autor:
Matthew R Allen, Erin McNerny, Mohammad Aref, Jason M Organ, Christopher L Newman, Brian McGowan, Tim Jang, David B Burr, Drew M Brown, Max Hammond, Paul R Territo, Chen Lin, Scott Persohn, Lei Jiang, Amanda A Riley, Brian P McCarthy, Gary D Hutchins, Joseph M Wallace
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181750 (2017)
A growing number of studies have investigated combination treatment as an approach to treat bone disease. The goal of this study was to investigate the combination of alendronate and raloxifene with a particular focus on mechanical properties. To ach
Externí odkaz:
https://doaj.org/article/69e88f7ab0404ba3bd53ff7795738462
Autor:
Keith G Avin, Neal X Chen, Jason M Organ, Chad Zarse, Kalisha O'Neill, Richard G Conway, Robert J Konrad, Robert L Bacallao, Matthew R Allen, Sharon M Moe
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159411 (2016)
Skeletal muscle atrophy and impaired muscle function are associated with lower health-related quality of life, and greater disability and mortality risk in those with chronic kidney disease (CKD). However, the pathogenesis of skeletal dysfunction in
Externí odkaz:
https://doaj.org/article/9fab6b85c9054d00800570163fd79134
Autor:
Christopher L Newman, Sharon M Moe, Neal X Chen, Max A Hammond, Joseph M Wallace, Jeffry S Nyman, Matthew R Allen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99262 (2014)
Chronic kidney disease (CKD), which leads tocortical bone loss and increasedporosity,increases therisk of fracture. Animal models have confirmed that these changes compromise whole bone mechanical properties. Estimates from whole bone testing suggest
Externí odkaz:
https://doaj.org/article/dbab2c7e5be54b2298e063cab5fda199
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106904 (2014)
The sympathetic nervous system (SNS) plays an important role in mediating bone remodeling. However, the exact role that beta-1 adrenergic receptors (beta1AR) have in this process has not been elucidated. We have previously demonstrated the ability of
Externí odkaz:
https://doaj.org/article/8e8b9fc6e3c24a1e9dd1d466deb9d972
Autor:
Corinne E. Metzger, Robert C. Moore, Alexander S. Pirkle, Landon Y. Tak, Josephina Rau, Jessica A. Bryan, Alexander Stefanov, Matthew R. Allen, Michelle A. Hook
Publikováno v:
Bone Reports, Vol 21, Iss , Pp 101761- (2024)
Spinal cord injury (SCI) leads to significant sublesional bone loss and high fracture rates. While loss of mechanical loading plays a significant role in SCI-induced bone loss, animal studies have demonstrated mechanical loading alone does not fully
Externí odkaz:
https://doaj.org/article/5453a134865147b6a3e4a6e66d13a86f