Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Matthew R, Rice"'
Autor:
Liseth Carmona-Pérez, Xavier Dagenais-Lussier, Linh T. Mai, Tanja Stögerer, Sharada Swaminathan, Stéphane Isnard, Matthew R. Rice, Betsy J. Barnes, Jean-Pierre Routy, Julien van Grevenynghe, Simona Stäger
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
HIV-1 infection is characterized by inflammation and a progressive decline in CD4+ T cell count. Despite treatment with antiretroviral therapy (ART), the majority of people living with HIV (PLWH) maintain residual levels of inflammation, a low degree
Externí odkaz:
https://doaj.org/article/f2823c61a0e14a9e9f33b2d74c271aa6
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Interferon Regulatory Factor 5 (IRF5) is one of nine members of the IRF family of transcription factors. Although initially discovered as a key regulator of the type I interferon and pro-inflammatory cytokine arm of the innate immune response, IRF5 h
Externí odkaz:
https://doaj.org/article/aeba889a33274fe2bc21c7eaffd3b506
Autor:
Zarina Brune, Dan Li, Su Song, Dan Iris Li, Isabel Castro, Rhea Rasquinha, Matthew R. Rice, Qin Guo, Kyle Kampta, Matthew Moss, Morgan Lallo, Erica Pimenta, Carter Somerville, Margaret Lapan, Victoria Nelson, Camila O. dos Santos, Lionel Blanc, Kevin Pruitt, Betsy J. Barnes
Publikováno v:
bioRxiv
SummaryDespite the progress made in identifying cellular factors and mechanisms that predict progression and metastasis, breast cancer remains the second leading cause of death for women in the US. Using The Cancer Genome Atlas and mouse models of sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d17d498084db7490259ce122c9735c
https://europepmc.org/articles/PMC10246023/
https://europepmc.org/articles/PMC10246023/
Publikováno v:
Biochemistry
Biosynthesis of the hydroxamate siderophore aerobactin requires the activity of four proteins encoded within the iuc operon. Recently, we biochemically reconstituted the biosynthetic pathway and structurally characterized IucA and IucC, two enzymes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80db158181419604fa37edd25b9fbca
https://doi.org/10.1021/acs.biochem.0c00250
https://doi.org/10.1021/acs.biochem.0c00250
Publikováno v:
The Journal of Immunology. 208:105.32-105.32
The recruitment of leukocytes to sites of infection is an essential component of the innate immune response to pathogens. Defects in leukocyte migration can render the host susceptible to recurrent infections. In our efforts to identify new mediators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15455fc4f43c03928a72b475e4b73391
https://doi.org/10.4049/jimmunol.208.supp.105.32
https://doi.org/10.4049/jimmunol.208.supp.105.32
Publikováno v:
The Journal of Immunology. 208:52.15-52.15
Toll-like receptors (TLRs) represent a subset of pathogen-recognition receptors (PRRs) employed by the innate immune system to detect pathogen-associated molecular patterns (PAMPs) and initiate the response to invading microbes. The transcription fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e847431f23aaa7e768c2f1a24c8a8ab1
https://doi.org/10.4049/jimmunol.208.supp.52.15
https://doi.org/10.4049/jimmunol.208.supp.52.15
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Interferon Regulatory Factor 5 (IRF5) is one of nine members of the IRF family of transcription factors. Although initially discovered as a key regulator of the type I interferon and pro-inflammatory cytokine arm of the innate immune response, IRF5 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da878a588bc814c65ef54d59330cfd7b
https://www.frontiersin.org/article/10.3389/fimmu.2020.01143/full
https://www.frontiersin.org/article/10.3389/fimmu.2020.01143/full
Autor:
Lisa S. Mydy, Eric J. Drake, Andrew M. Gulick, Courtney C. Aldrich, Daniel Bailey, Evan M. Alexander, Matthew R. Rice
Publikováno v:
Journal of Biological Chemistry. 293:7841-7852
Aerobactin, a citryl-hydroxamate siderophore, is produced by a number of pathogenic Gram-negative bacteria to aid in iron assimilation. Interest in this well-known siderophore was reignited by recent investigations suggesting that it plays a key role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a28580dec250c2e84ea6cb1241b84e9
https://doi.org/10.1074/jbc.ra118.002798
https://doi.org/10.1074/jbc.ra118.002798
Publikováno v:
The Journal of Immunology. 204:151.22-151.22
The transcription factor IRF5 modulates human B cell activation, proliferation, and plasmablast differentiation via an intrinsic mechanism. Targeted knockdown of IRF5 in human primary naïve B cells revealed a significant reduction in CD19+CD86+ B ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee6acae94ee45011e7e8c63f99051030
https://doi.org/10.4049/jimmunol.204.supp.151.22
https://doi.org/10.4049/jimmunol.204.supp.151.22
Autor:
Daniel C, Bailey, Evan, Alexander, Matthew R, Rice, Eric J, Drake, Lisa S, Mydy, Courtney C, Aldrich, Andrew M, Gulick
Publikováno v:
The Journal of biological chemistry. 293(20)
Aerobactin, a citryl-hydroxamate siderophore, is produced by a number of pathogenic Gram-negative bacteria to aid in iron assimilation. Interest in this well-known siderophore was reignited by recent investigations suggesting that it plays a key role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f07cbc873e2f936abf22ae7276cb5ed
https://pubmed.ncbi.nlm.nih.gov/29618511
https://pubmed.ncbi.nlm.nih.gov/29618511