Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Matthew R, Reinhard"'
Autor:
Junliang, Hao, James P, Beck, John M, Schaus, Joseph H, Krushinski, Qi, Chen, Christopher D, Beadle, Paloma, Vidal, Matthew R, Reinhard, Bruce A, Dressman, Steven M, Massey, Serge L, Boulet, Michael P, Cohen, Brian M, Watson, David, Tupper, Kevin M, Gardinier, Jason, Myers, Anette M, Johansson, Jeffery, Richardson, Daniel S, Richards, Erik J, Hembre, David M, Remick, David A, Coates, Rajni M, Bhardwaj, Benjamin A, Diseroad, David, Bender, Greg, Stephenson, Craig D, Wolfangel, Nuria, Diaz, Brian G, Getman, Xu-Shan, Wang, Beverly A, Heinz, Jeff W, Cramer, Xin, Zhou, Deanna L, Maren, Julie F, Falcone, Rebecca A, Wright, Stephen N, Mitchell, Guy, Carter, Charles R, Yang, Robert F, Bruns, Kjell A, Svensson
Publikováno v:
Journal of medicinal chemistry. 62(19)
Clinical development of catechol-based orthosteric agonists of the dopamine D1 receptor has thus far been unsuccessful due to multiple challenges. To address these issues, we identified LY3154207 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38771cd6f379be26a1a0dc76826df19b
https://pubmed.ncbi.nlm.nih.gov/31532644
https://pubmed.ncbi.nlm.nih.gov/31532644
Autor:
James A, Monn, Lourdes, Prieto, Lorena, Taboada, Junliang, Hao, Matthew R, Reinhard, Steven S, Henry, Christopher D, Beadle, Lesley, Walton, Teresa, Man, Helene, Rudyk, Barry, Clark, David, Tupper, S Richard, Baker, Carlos, Lamas, Carlos, Montero, Alicia, Marcos, Jaime, Blanco, Mark, Bures, David K, Clawson, Shane, Atwell, Frances, Lu, Jing, Wang, Marijane, Russell, Beverly A, Heinz, Xushan, Wang, Joan H, Carter, Brian G, Getman, John T, Catlow, Steven, Swanson, Bryan G, Johnson, David B, Shaw, David L, McKinzie
Publikováno v:
Journal of medicinal chemistry. 58(18)
Identification of orthosteric mGlu(2/3) receptor agonists capable of discriminating between individual mGlu2 and mGlu3 subtypes has been highly challenging owing to the glutamate-site sequence homology between these proteins. Herein we detail the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3e08f0001b2fb8da6ecccee3a121fe3
https://pubmed.ncbi.nlm.nih.gov/26313429
https://pubmed.ncbi.nlm.nih.gov/26313429