Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Matthew R, Meyer"'
1
Akademický článek
PrecivityAD2™ Blood Test: Analytical Validation of an LC-MS/MS Assay for Quantifying Plasma Phospho-tau217 and Non-Phospho-tau217 Peptide Concentrations That Are Used with Plasma Amyloid-β42/40 in a Multianalyte Assay with Algorithmic Analysis for Detecting Brain Amyloid Pathology
Autor: Stephanie M. Eastwood, Matthew R. Meyer, Kristopher M. Kirmess, Traci L. Wente-Roth, Faith Irvin, Mary S. Holubasch, Philip B. Verghese, Tim West, Joel B. Braunstein, Kevin E. Yarasheski, John H. Contois
Publikováno v: Diagnostics, Vol 14, Iss 16, p 1739 (2024)
Alzheimer’s disease (AD) is a progressive irreversible neurodegenerative disorder that represents a major global public health concern. Traditionally, AD is diagnosed using cerebrospinal fluid biomarker analysis or brain imaging modalities. Recentl
Externí odkaz: https://doaj.org/article/28e6fa8ca16042328d46beeee1e30200
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2
Akademický článek
Independent study demonstrates amyloid probability score accurately indicates amyloid pathology
Autor: Ilana Fogelman, Tim West, Joel B. Braunstein, Philip B. Verghese, Kristopher M. Kirmess, Matthew R. Meyer, John H. Contois, Eli Shobin, Kyle L. Ferber, Jake Gagnon, Carrie E. Rubel, Danielle Graham, Randall J. Bateman, David M. Holtzman, Shuguang Huang, Joanne Yu, Sha Yang, Kevin E. Yarasheski
Publikováno v: Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 765-778 (2023)
Abstract Background The amyloid probability score (APS) is the model read‐out of the analytically validated mass spectrometry‐based PrecivityAD® blood test that incorporates the plasma Aβ42/40 ratio, ApoE proteotype, and age to identify the lik
Externí odkaz: https://doaj.org/article/93cd3d1753d44499bd17189a775abc36
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3
Akademický článek
Comparison of plasma and CSF biomarkers in predicting cognitive decline
Autor: Andrew J. Aschenbrenner, Yan Li, Rachel L. Henson, Katherine Volluz, Jason Hassenstab, Philip Verghese, Tim West, Matthew R. Meyer, Kristopher M. Kirmess, Anne M. Fagan, Chengjie Xiong, David Holtzman, John C. Morris, Randall J. Bateman, Suzanne E. Schindler
Publikováno v: Annals of Clinical and Translational Neurology, Vol 9, Iss 11, Pp 1739-1751 (2022)
Abstract Objectives Concentrations of amyloid‐β peptides (Aβ42/Aβ40) and neurofilament light (NfL) can be measured in plasma or cerebrospinal fluid (CSF) and are associated with Alzheimer’s disease brain pathology and cognitive impairment. Thi
Externí odkaz: https://doaj.org/article/8f7c8d145d2b4e17b9754fd515d4d64c
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4
Akademický článek
A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis
Autor: Tim West, Kristopher M. Kirmess, Matthew R. Meyer, Mary S. Holubasch, Stephanie S. Knapik, Yan Hu, John H. Contois, Erin N. Jackson, Scott E. Harpstrite, Randall J. Bateman, David M. Holtzman, Philip B. Verghese, Ilana Fogelman, Joel B. Braunstein, Kevin E. Yarasheski
Publikováno v: Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background The development of blood-based biomarker tests that are accurate and robust for Alzheimer’s disease (AD) pathology have the potential to aid clinical diagnosis and facilitate enrollment in AD drug trials. We developed a high-res
Externí odkaz: https://doaj.org/article/c91cadfca9d9471da9fe34743049c0b5
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5
Plasma Aβ42/Aβ40 Ratios in Older People With Human Immunodeficiency Virus
Autor: Sarah A Cooley, Brittany Nelson, Anna Boerwinkle, Kevin E Yarasheski, Kris M Kirmess, Matthew R Meyer, Suzanne E Schindler, John C Morris, Anne Fagan, Beau M Ances, Jane A O’Halloran
Publikováno v: Clinical Infectious Diseases. 76:1776-1783
Background As people with human immunodeficiency virus (HIV) (PWH) age, it remains unclear whether they are at higher risk for age-related neurodegenerative disorders—for example, Alzheimer disease (AD)—and, if so, how to differentiate HIV-associ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8bdb9c0e76cdb42353a15bc2b454d4d
https://doi.org/10.1093/cid/ciad001
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