Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Matthew R, Holahan"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionSocial memory involves social recognition: the ability to discriminate between two or more conspecifics when one has been previously encountered. The CA2 region of the hippocampus has been implicated in social memory, as lesions and dysfu
Externí odkaz:
https://doaj.org/article/76bea7ee07cc49a7ad87d7e2c3a88461
Autor:
Nikolaos Tzakis, Matthew R. Holahan
Publikováno v:
IBRO Reports, Vol 8, Iss , Pp 91-100 (2020)
Preadolescent development is characterized by a reorganization of connectivity within and between brain regions that coincides with the emergence of complex behaviors. During the preadolescent period, the rodent hippocampus and regions of the frontal
Externí odkaz:
https://doaj.org/article/4bd5619a4caa472ca3826183bbef622e
Autor:
Brendan Hoffe, Matthew R. Holahan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The biological response of brain tissue to biomechanical strain are of fundamental importance in understanding sequela of a brain injury. The time after impact can be broken into four main phases: hyperacute, acute, subacute and chronic. It is crucia
Externí odkaz:
https://doaj.org/article/f5afac4dee6c43c6972b054bb8bc58c6
Publikováno v:
Journal of Parkinson's Disease. 12:2339-2352
The contribution of the microbiota to induce gastrointestinal inflammation is hypothesized to be a key component of alpha-synuclein (aSyn) aggregation within the gastrointestinal (GI) tract in the pathological progression of Parkinson’s disease (PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb6110d334e4f85f37f62200d49e01e
https://doi.org/10.3233/jpd-223461
https://doi.org/10.3233/jpd-223461
Autor:
Nikolaos Tzakis, Matthew R. Holahan
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
The CA2 region of the hippocampus is a somewhat obscure area lacking in an understanding of its form and function. Until recently, the CA2 has been thought of as merely an extension of the CA3, with some referring to it as the CA3a region. Recent inv
Externí odkaz:
https://doaj.org/article/a551c11267e746818f82c21c772922f6
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
An important aspect concerning the underlying nature of memory function is an understanding of how memories are acquired and lost. The stability, and ultimate demise, of memory over the lifespan of an organism remains a critical topic in determining
Externí odkaz:
https://doaj.org/article/bd2a3ea42cc34dc5a2c473a64a829b50
Autor:
Brendan Hoffe, Matthew R. Holahan
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
In recent years, the move to study neurodegenerative disease using larger animal models with brains that are more similar to humans has gained interest. While pigs have been used for various biomedical applications and research, it has only been rece
Externí odkaz:
https://doaj.org/article/d51a935ff24a41e28bd3f79f0eedd6a1
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Rationale: Incubation of craving is a phenomenon whereby responding for cues associated with a reward increases over extended periods of abstinence. Both contingent and non-contingent behavioral designs have been used to study the incubation of cravi
Externí odkaz:
https://doaj.org/article/10a262d8dd084018b04de81562393a18
Autor:
Isabelle Boutet, Charles A. Collin, Lindsey S. MacLeod, Claude Messier, Matthew R. Holahan, Elizabeth Berry-Kravis, Reno M. Gandhi, Cary S. Kogan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
To generate meaningful information, translational research must employ paradigms that allow extrapolation from animal models to humans. However, few studies have evaluated translational paradigms on the basis of defined validation criteria. We outlin
Externí odkaz:
https://doaj.org/article/7cf6800844ef4d399e59424c5ce0c331
Autor:
Matthew R. Holahan
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
In a number of animal species, the growth-associated protein (GAP), GAP-43 (aka: F1, neuromodulin, B-50, G50, pp46), has been implicated in the regulation of presynaptic vesicular function and axonal growth and plasticity via its own biochemical prop
Externí odkaz:
https://doaj.org/article/33729256ecb445fd865edb9b281aa1ec