Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Matthew R, Dreher"'
Autor:
Timo L. M. ten Hagen, Matthew R. Dreher, Sara Zalba, Ann L. B. Seynhaeve, Mohamadreza Amin, Li Li, Dieter Haemmerich
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Ten Hagen et al. developed a computational model to simulate intravascular triggered drug delivery systems (IV-DDS), which they validated using quantitative intravital microscopy in mice. Their model potentially enables the engineering of more effica
Externí odkaz:
https://doaj.org/article/292013dcfbbe4560a8cff83d92bc8106
Autor:
Alexander S. Pasciak, Sasicha Manupipatpong, Ferdinand K. Hui, Larry Gainsburg, Rebecca Krimins, M. Christine Zink, Cory F. Brayton, Meaghan Morris, Jaime Sage, Danielle R. Donahue, Matthew R. Dreher, Dara L. Kraitchman, Clifford R. Weiss
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Purpose To evaluate the safety, feasibility, and preliminary efficacy of yttrium-90 (90Y) radioembolization (RE) as a minimally invasive treatment in a canine model with presumed spontaneous brain cancers. Materials Three healthy research do
Externí odkaz:
https://doaj.org/article/29771edf9a704377bd6e1d984ca2b8fc
Autor:
Alexander S. Pasciak, Sasicha Manupipatpong, Ferdinand K. Hui, Larry Gainsburg, Rebecca Krimins, M. Christine Zink, Cory F. Brayton, Meaghan Morris, Jaime Sage, Danielle R. Donahue, Matthew R. Dreher, Dara L. Kraitchman, Clifford R. Weiss
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-3 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/51bb4828656f4796b8baea4313064668
Autor:
Mark W. Dewhirst, David Needham, Timo L.M. ten Hagen, Gerben A. Koning, Ashutosh Chilkoti, Won Park, Gabi Hanna, Shiva Das, Matthew R. Dreher, Andrew J. Simnick, Ji-Young Park, Chelsea D. Landon, Lars H. Lindner, Ashley A. Manzoor
PDF file - 83K, Citation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e66045944b81cc05c5d9096f9c12db
https://doi.org/10.1158/0008-5472.22393964.v1
https://doi.org/10.1158/0008-5472.22393964.v1
Supplementary Figure 1 from Thermal Cycling Enhances the Accumulation of a Temperature-Sensitive Biopolymer in Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3236c73255abb3fb3def7afa98aaf2e
https://doi.org/10.1158/0008-5472.22370433
https://doi.org/10.1158/0008-5472.22370433
Autor:
Mark W. Dewhirst, David Needham, Timo L.M. ten Hagen, Gerben A. Koning, Ashutosh Chilkoti, Won Park, Gabi Hanna, Shiva Das, Matthew R. Dreher, Andrew J. Simnick, Ji-Young Park, Chelsea D. Landon, Lars H. Lindner, Ashley A. Manzoor
AVI file - 34.5MB, Real-time intravascular release of doxorubicin from Dox-TSL and subsequent redistribution of drug in B16 melanoma tumor tissue. The video shows drug (red) delivered over the first 20min, at 20x magnification. The eNOS-GFPtg mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7566102854984d337f797e7992c274
https://doi.org/10.1158/0008-5472.22393952
https://doi.org/10.1158/0008-5472.22393952
Autor:
Mark W. Dewhirst, David Needham, Timo L.M. ten Hagen, Gerben A. Koning, Ashutosh Chilkoti, Won Park, Gabi Hanna, Shiva Das, Matthew R. Dreher, Andrew J. Simnick, Ji-Young Park, Chelsea D. Landon, Lars H. Lindner, Ashley A. Manzoor
AVI file - 41.7MB, Real-time drug delivery of free doxorubicin and Dox-TSL in heated FaDu tumor tissue. The blood vessels are highlighted in green and drug is red. The video shows drug delivered over the first 20min, at 20x magnification. Free drug q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47626bdd01973a44e087fcf05cac1f41
https://doi.org/10.1158/0008-5472.22393958
https://doi.org/10.1158/0008-5472.22393958
Autor:
Mark W. Dewhirst, David Needham, Timo L.M. ten Hagen, Gerben A. Koning, Ashutosh Chilkoti, Won Park, Gabi Hanna, Shiva Das, Matthew R. Dreher, Andrew J. Simnick, Ji-Young Park, Chelsea D. Landon, Lars H. Lindner, Ashley A. Manzoor
Traditionally, the goal of nanoparticle-based chemotherapy has been to decrease normal tissue toxicity by improving drug specificity to tumors. The enhanced permeability and retention effect can permit passive accumulation into tumor interstitium. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b119116676ac980f585d26c62d68ae6d
https://doi.org/10.1158/0008-5472.c.6503915.v1
https://doi.org/10.1158/0008-5472.c.6503915.v1
The delivery of anticancer therapeutics to solid tumors remains a critical problem in the treatment of cancer. This study reports a new methodology to target a temperature-responsive macromolecular drug carrier, an elastin-like polypeptide (ELP) to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a785e73d394960b4b5578f6f8dbfbc2
https://doi.org/10.1158/0008-5472.c.6496398
https://doi.org/10.1158/0008-5472.c.6496398
Autor:
Matthew R. Dreher, Pedro Garcia, Sean L. Willis, Andrew L. Lewis, Shuning Bian, Daniel F. Daly, Marcus Caine, Alexander Henman, Yiqing Tang, Robert Carlisle, Eleanor Stride
Understanding the intra-tumoral distribution of chemotherapeutic drugs is extremely important in predicting therapeutic outcome. Tissue mimicking gel phantoms are useful for studying drug distribution in vitro but quantifying distribution is laboriou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a906a92ac6820943611763ad2c821ea
https://doi.org/10.1016/j.ejps.2021.105772
https://doi.org/10.1016/j.ejps.2021.105772