Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Matthew R, Berwick"'
Autor:
Louise N. Slope, Jack A. Bryant, Matthew R. Berwick, Naa Dei Nikoi, Anna F. A. Peacock, Lily Riordan, Felicity de Cogan
Publikováno v:
Current Eye Research. 46:751-757
The development of a polyarginine cell-penetrating peptide (CPP) could enable the treatment of age-related macular degeneration, with drugs like bevacizumab, to be administered using eye drops instead of intravitreal injections. Topical formulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744843fad820791fdddf360bcce44c64
https://doi.org/10.1080/02713683.2020.1830117
https://doi.org/10.1080/02713683.2020.1830117
Autor:
Heping Xu, Judith Lechner, Matthew R. Berwick, Felicity de Cogan, Aisling Lynch, Robert A H Scott, Peter J Morgan-Warren, Ann Logan, Lisa J Hill, Anna F. A. Peacock, Mei Chen
Publikováno v:
de Cogan, F, Hill, L J, Lynch, A, Morgan-Warren, P J, Lechner, J, Berwick, M R, Peacock, A F A, Chen, M, Scott, R A H, Xu, H & Logan, A 2017, ' Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides ', Investigative ophthalmology & visual science, vol. 58, no. 5, pp. 2578-2590 . https://doi.org/10.1167/iovs.16-20072
Purpose: To evaluate the efficacy of anti-VEGF agents for treating choroidal neovascularization (CNV) when delivered topically using novel cell-penetrating peptides (CPPs) compared with delivery by intravitreal (ivit) injection.Methods: CPP toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be72947f6ceaaf0b6be76c58ebccdab
https://pure.qub.ac.uk/en/publications/topical-delivery-of-antivegf-drugs-to-the-ocular-posterior-segment-using-cellpenetrating-peptides(c69f21f4-fce1-4e50-9cea-bf3528ae97fa).html
https://pure.qub.ac.uk/en/publications/topical-delivery-of-antivegf-drugs-to-the-ocular-posterior-segment-using-cellpenetrating-peptides(c69f21f4-fce1-4e50-9cea-bf3528ae97fa).html
Autor:
Anna F. A. Peacock, Matthew R. Berwick, Beryl Oppenheim, Felicity de Cogan, Olachi Anuforom, Antonio Belli, Julie E. Gough, Ann Logan, Erik A. B. Hughes, Artemis Stamboulis, Leigh Townsend, Robert A. H. Scott, Richard L. Williams, Mark A. Webber, Liam M. Grover, Fenella D. Halstead
Publikováno v:
Townsend, L, Williams, R L, Anuforom, O, Berwick, M R, Halstead, F, Hughes, E, Stamboulis, A, Oppenheim, B, Gough, J, Grover, L, Scott, R A H, Webber, M, Peacock, A F A, Belli, A, Logan, A & De Cogan, F 2017, ' Antimicrobial peptide coatings for hydroxyapatite : Electrostatic and covalent attachment of antimicrobial peptides to surfaces ', Journal of the Royal Society Interface, vol. 14, no. 126, 20160657 . https://doi.org/10.1098/rsif.2016.0657
The interface between implanted devices and their host tissue is complex and is often optimized for maximal integration and cell adhesion. However, this also gives a surface suitable for bacterial colonization. We have developed a novel method of mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae0ef1da262b47e5a5a2c64b7b37bf9
https://www.research.manchester.ac.uk/portal/en/publications/antimicrobial-peptide-coatings-for-hydroxyapatite(f03aadd6-dfdf-4e0d-8904-d8143045a472).html
https://www.research.manchester.ac.uk/portal/en/publications/antimicrobial-peptide-coatings-for-hydroxyapatite(f03aadd6-dfdf-4e0d-8904-d8143045a472).html
Autor:
Matthew R, Berwick, David J, Lewis, Andrew W, Jones, Rosemary A, Parslow, Timothy R, Dafforn, Helen J, Cooper, John, Wilkie, Zoe, Pikramenou, Melanie M, Britton, Anna F A, Peacock
Publikováno v:
Journal of the American Chemical Society
A new peptide sequence (MB1) has been designed which, in the presence of a trivalent lanthanide ion, has been programmed to self-assemble to form a three stranded metallo-coiled coil, Ln(III)(MB1)3. The binding site has been incorporated into the hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0e8be7f28962e8d0cf32fd35b0c2c28
https://pubmed.ncbi.nlm.nih.gov/24405157
https://pubmed.ncbi.nlm.nih.gov/24405157
Autor:
Melanie M. Britton, Stephen E. Harding, Caitlin F. Smith, Anna F. A. Peacock, Louise N. Slope, Matthew R. Berwick, Arthur J. Rowe, Gary G. Adams, Siobhan M. King, Sarah L. Newton, Richard B. Gillis
Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2420ffccd0115f5404ac3fb313970ce