Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Matthew P. Vincenti"'
Autor:
Sabrina Ceeraz, Susan K. Eszterhas, Petra A. Sergent, David A. Armstrong, Alix Ashare, Thomas Broughton, Li Wang, Dov Pechenick, Christopher M. Burns, Randolph J. Noelle, Matthew P. Vincenti, Roy A. Fava
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Abstract Background In addition to activated T cells, the immune checkpoint inhibitor “V domain-containing Ig suppressor of T-cell activation” (VISTA) is expressed by myeloid cell types, including macrophages and neutrophils. The importance of VI
Externí odkaz:
https://doaj.org/article/5d72d8c1bf0948c0bbccc700bc1f2200
Autor:
Marina Trefethen, Luke Rozema, Matthew P. Vincenti, Paula P. Schnurr, Brian Shiner, Bradley V. Watts, Martin Kulldorff, Krista F. Huybrechts, Jaimie L. Gradus, Jiang Gui, Jenna A. Forehand, Tammy Jiang
Publikováno v:
Biol Psychiatry
Background Despite the prevalence and negative impact of posttraumatic stress disorder (PTSD), there are few medications approved by the United States Food and Drug Administration (FDA) for treatment, and approved medications do not work well enough.
Publikováno v:
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry. 46(4)
Objective The authors evaluated the distribution of psychiatry residency positions funded by the Department of Veterans Affairs between 2014 and 2020 with respect to geographic location and hospital patient population rurality. Methods The authors co
Autor:
Randolph J. Noelle, Susan K. Eszterhas, Li Wang, Christopher M. Burns, David A. Armstrong, Alix Ashare, Matthew P. Vincenti, Petra A. Sergent, Sabrina Ceeraz, Thomas Broughton, Dov A. Pechenick, Roy A. Fava
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Background In addition to activated T cells, the immune checkpoint inhibitor “V domain-containing Ig suppressor of T-cell activation” (VISTA) is expressed by myeloid cell types, including macrophages and neutrophils. The importance of VISTA expre
Publikováno v:
Cancer Medicine
Effective treatment of metastatic renal cell carcinoma (RCC) remains a major medical concern, as these tumors are refractory to standard therapies and prognosis is poor. Although molecularly targeted therapies have shown some promise in the treatment
Publikováno v:
Molecular Cancer Research. 7:1517-1524
Matrix metalloproteinase-1 (MMP-1) is an inflammation-inducible neutral protease that mediates extracellular matrix remodeling and promotes tumor invasion. In this study, we examined the activation of MMP-1 gene expression in A549 lung carcinoma cell
Autor:
Dolores Cortez, Srinivas Mummidi, Jeffrey L. Barnes, Matthew P. Vincenti, Anthony J. Valente, Marc D. Feldman, Bjorn Steffensen, Bysani Chandrasekar
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H3356-H3365
Matrix metalloproteinases (MMPs) degrade collagen and mediate tissue remodeling. The novel cytokine IL-17 is expressed during various inflammatory conditions and modulates MMP expression. We investigated the effect of IL-17 on MMP-1 expression in pri
Publikováno v:
Osteoarthritis and Cartilage. 15(4):431-441
Interleukin-1beta (IL-1beta) stimulates collagenase-1 (Matrix Metalloproteinase-1 (MMP-1)) expression in articular chondrocytes, leading to cleavage of type II collagen and irreversible cartilage degradation. The nuclear factor-kappa B (NF-kappaB) pa
Publikováno v:
Arthritis & Rheumatism. 46:3230-3239
OBJECTIVE To define the role of Bcl-3, a member of the inhibitor of nuclear factor kappaB (NF-kappaB) family and a known regulator of NF-kappaB, in interleukin-1 (IL-1)-induced matrix metalloproteinase 1 (MMP-1) transcription in chondrocytes and syno
Publikováno v:
Nucleic Acids Research. 29:4361-4372
Osteoarthritic chondrocytes secrete matrix metalloproteinase-13 (MMP-13) in response to interleukin-1 (IL-1), causing digestion of type II collagen in cartilage. Using chondrocytic cells, we previously determined that IL-1 induced a strong MMP-13 tra