Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Matthew P. Torres"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The extracellular matrix (ECM) is a protein polymer network that physically supports cells within a tissue. It acts as an important physical and biochemical stimulus directing cell behaviors. For fibronectin (Fn), a predominant component of
Externí odkaz:
https://doaj.org/article/b03f52c719e54085b999ad36836d36fa
Autor:
Emily G. Saccuzzo, Mubark D. Mebrat, Hailee F. Scelsi, Minjoo Kim, Minh Thu Ma, Xinya Su, Shannon E. Hill, Elisa Rheaume, Renhao Li, Matthew P. Torres, James C. Gumbart, Wade D. Van Horn, Raquel L. Lieberman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Studies of folded-to-misfolded transitions using model protein systems reveal a range of unfolding needed for exposure of amyloid-prone regions for subsequent fibrillization. Here, we probe the relationship between unfolding and aggregation
Externí odkaz:
https://doaj.org/article/d4c43b083a34447bb38dec82f348044d
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1504-1515 (2018)
Summary: Heterotrimeric G proteins (Gαβγ) are essential transducers in G protein signaling systems in all eukaryotes. In yeast, G protein signaling differentially activates mitogen-activated protein kinases (MAPKs)—Fus3 and Kss1—a phenomenon c
Externí odkaz:
https://doaj.org/article/d473f429fdad4e96a15ebd52faf2b949
Autor:
Hyojung Kim, Courtney M. Moore, Santi Mestre-Fos, David A. Hanna, Loren Dean Williams, Amit R. Reddi, Matthew P. Torres
Hemeb(iron protoporphyrin IX) plays important roles in biology as a metallocofactor and signaling molecule. However, the targets of heme signaling and the network of proteins that mediate the exchange of heme from sites of synthesis or uptake to heme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9e79520bf8cbcabb9e004ef8c8f3fc7
https://doi.org/10.1101/2022.10.11.511733
https://doi.org/10.1101/2022.10.11.511733
Autor:
Meral Tunc-Ozdemir, Bo Li, Dinesh K. Jaiswal, Daisuke Urano, Alan M. Jones, Matthew P. Torres
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
Heterotrimeric G proteins function in development, biotic, and abiotic stress responses, hormone signaling as well as sugar sensing. We previously proposed that discrimination of these various external signals in the G protein pathway is accomplished
Externí odkaz:
https://doaj.org/article/b814f029419c4c37b1e01ede5dfff71d
Autor:
Henry M Dewhurst, Matthew P Torres
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172572 (2017)
Post-translational modifications (PTMs) provide an extensible framework for regulation of protein behavior beyond the diversity represented within the genome alone. While the rate of identification of PTMs has rapidly increased in recent years, our k
Externí odkaz:
https://doaj.org/article/ee1645ac8b0b4a84835a5735f2f89aa9
Autor:
Claudia Montllor-Albalate, Hyojung Kim, Anna E. Thompson, Alex P. Jonke, Matthew P. Torres, Amit R. Reddi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Cu/Zn superoxide dismutase (Sod1) is a key antioxidant enzyme, and its importance is underscored by the fact that its ablation in cell and animal models results in oxidative stress; metabolic defects; and reductions in cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b94d7014196012d33d153331c50618d
https://pubmed.ncbi.nlm.nih.gov/34969852
https://pubmed.ncbi.nlm.nih.gov/34969852
Autor:
James C. Gumbart, Matthew P. Torres, Shilpa Choudhury, Yui Tik Pang, Zahra Nassiri Toosi, Ruth Austin, Wei Li, Xinya Su
Publikováno v:
Sci Signal
Intrinsically disordered regions (IDRs) in proteins are often targets of combinatorial posttranslational modifications, which serve to regulate protein structure and function. Emerging evidence suggests that the N-terminal tails of G protein γ subun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5505d71defbad7f31eef62b03707cb
https://pubmed.ncbi.nlm.nih.gov/34158397
https://pubmed.ncbi.nlm.nih.gov/34158397
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
The inherited form of open angle glaucoma arises due to a toxic gain-of-function intracellular misfolding event involving a mutated myocilin olfactomedin domain (OLF). Mutant myocilin is recognized by the endoplasmic reticulum (ER)-resident heat shoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61587dfc755e9c65cc58ea9d5f32a3cc
http://link.springer.com/article/10.1038/s41598-019-48751-8
http://link.springer.com/article/10.1038/s41598-019-48751-8
The extracellular matrix (ECM) is a protein polymer network that physically supports cells within a tissue and also acts as an important biochemical stimulus directing cell behaviors. For fibronectin, a predominant component of the ECM, these physica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a720b92357304af743277827ffa5a2f6
https://doi.org/10.21203/rs.3.rs-468701/v1
https://doi.org/10.21203/rs.3.rs-468701/v1