Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Matthew P. Patricelli"'
Autor:
Yi Liu, Pingda Ren, Anjali Babbar, Sarah J. Firdaus, Jeffrey H. Chen, Tess Ely, Jun Feng, Jeff M. Kucharski, Yuching Chen, Linda V. Kessler, Ulf Peters, Rasmus Hansen, Lian-Sheng Li, Matthew R. Janes, Matthew P. Patricelli
Supplementary Table 1. Biochemical and Cell engagement SAR. Supplementary Table 2. Data collection and refinement statistics (Molecular replacement). Supplementary Table 3. Selectivity of ARS-853 across KRAS isoforms and GTP vs. GDP states. Supplemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb4c1da5f413c618429e4a216ba9b29
https://doi.org/10.1158/2159-8290.22531619
https://doi.org/10.1158/2159-8290.22531619
Autor:
Nathanael S. Gray, David M. Sabatini, Kwok-Kin Wong, Pasi A. Janne, Stephen J. Elledge, Danny M. Chou, Kathryn D. Held, Hidemasa Kawamura, Abigail Altabef, Tanya Tupper, Yuchuan Wang, Matthew P. Patricelli, Seong A. Kang, Carson C. Thoreen, Mario Niepel, Dalia Ercan, Peng Gao, Kenneth D. Westover, Jinhua Wang, Nicholas P. Kwiatkowski, Yan Liu, Wooyoung Hur, Xin Zhang, Sivapriya Kirubakaran, Chunxiao Xu, Qingsong Liu
PDF file - 719K, Supplemental figure 1. Torin2 on PC-3 wide type cell line, the IB was made after 30 min treatment of drug at indicated concentrations. Supplemental figure 2. Torin1, Torin2, AZD8055 and BEZ235 on HeLa and HCT-116 cell line at differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f1b766942775ec1d341f6520972504
https://doi.org/10.1158/0008-5472.22398726.v1
https://doi.org/10.1158/0008-5472.22398726.v1
Autor:
Nathanael S. Gray, David M. Sabatini, Kwok-Kin Wong, Pasi A. Janne, Stephen J. Elledge, Danny M. Chou, Kathryn D. Held, Hidemasa Kawamura, Abigail Altabef, Tanya Tupper, Yuchuan Wang, Matthew P. Patricelli, Seong A. Kang, Carson C. Thoreen, Mario Niepel, Dalia Ercan, Peng Gao, Kenneth D. Westover, Jinhua Wang, Nicholas P. Kwiatkowski, Yan Liu, Wooyoung Hur, Xin Zhang, Sivapriya Kirubakaran, Chunxiao Xu, Qingsong Liu
PDF file - 401K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfd6389bcfe5cc37d8e136047ce9803
https://doi.org/10.1158/0008-5472.22398723.v1
https://doi.org/10.1158/0008-5472.22398723.v1
Autor:
Nathanael S. Gray, David M. Sabatini, Kwok-Kin Wong, Pasi A. Janne, Stephen J. Elledge, Danny M. Chou, Kathryn D. Held, Hidemasa Kawamura, Abigail Altabef, Tanya Tupper, Yuchuan Wang, Matthew P. Patricelli, Seong A. Kang, Carson C. Thoreen, Mario Niepel, Dalia Ercan, Peng Gao, Kenneth D. Westover, Jinhua Wang, Nicholas P. Kwiatkowski, Yan Liu, Wooyoung Hur, Xin Zhang, Sivapriya Kirubakaran, Chunxiao Xu, Qingsong Liu
PDF file - 69K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b19dcaaff2b32304691f7dfcabff892
https://doi.org/10.1158/0008-5472.22398729
https://doi.org/10.1158/0008-5472.22398729
Autor:
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172649 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0152934.].
Externí odkaz:
https://doaj.org/article/a8fee0abbac8433b9e3e6fd4953734b3
Autor:
Tinghu Zhang, Edward T. Chouchani, Nathanael S. Gray, Matthew P. Patricelli, Milka Kostic, Lyn H. Jones, Jianwei Che, Wenchao Lu
Publikováno v:
RSC Chemical Biology
Targeted covalent inhibitors have regained widespread attention in drug discovery and have emerged as powerful tools for basic biomedical research. Fueled by considerable improvements in mass spectrometry sensitivity and sample processing, chemoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f198e962ae30072c0d7dd8a499287189
http://europepmc.org/articles/PMC8341086
http://europepmc.org/articles/PMC8341086
Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.
Autor:
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152934 (2016)
We describe the identification of a novel, tumor-specific missense mutation in the active site of casein kinase 1α (CSNK1A1) using activity-based proteomics. Matched normal and tumor colon samples were analyzed using an ATP acyl phosphate probe in a
Externí odkaz:
https://doaj.org/article/ffc6200c89354154984d306f8d950e36
Autor:
Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, Nilotpal Roy, Justine P. Lu, Landon R. Whitby, Jaclyn C. Brannon, Albert Parker, Joel M. Chick, Christie L. Eissler, Ashley Wong, Joe L. Rodriguez, Socorro Rodiles, Kim Masuda, John R. Teijaro, Gabriel M. Simon, Matthew P. Patricelli, Benjamin F. Cravatt
The JAK family of non-receptor tyrosine kinases includes four subtypes (JAK1, JAK2, JAK3, and TYK2) and is responsible for signal transduction downstream of diverse cytokine receptors. JAK inhibitors have emerged as important therapies for immuno(onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993a7767159730d69ddcc97d83645185
https://doi.org/10.1101/2022.01.31.478302
https://doi.org/10.1101/2022.01.31.478302
Autor:
Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, Nilotpal Roy, Justine P. Lu, Landon R. Whitby, Elva Ye, Jaclyn C. Brannon, Albert Parker, Joel M. Chick, Christie L. Eissler, Ashley J. Wong, Joe L. Rodriguez, Socorro Rodiles, Kim Masuda, John R. Teijaro, Gabriel M. Simon, Matthew P. Patricelli, Benjamin F. Cravatt
Publikováno v:
Nature Chemical Biology. 18:1288-1288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::275e9db8da4441d7c34e8f187f2398ea
https://doi.org/10.1038/s41589-022-01181-6
https://doi.org/10.1038/s41589-022-01181-6
Autor:
Nathanael S. Gray, Wenchao Lu, Tinghu Zhang, Milka Kostic, Jianwei Che, Edward T. Chouchani, Matthew P. Patricelli, Lyn H. Jones
Publikováno v:
RSC Chemical Biology. 2:670-671
Correction for ‘Fragment-based covalent ligand discovery’ by Wenchao Lu et al., RSC Chem. Biol., 2021, DOI: 10.1039/d0cb00222d.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fe50568640f4aebee23980c153ea27b
https://doi.org/10.1039/d1cb90008k
https://doi.org/10.1039/d1cb90008k