Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Matthew P. Mullarkey"'
Autor:
Upasana Sahu, Matthew P. Mullarkey, Guangsheng Pei, Zhongming Zhao, Bangxing Hong, Balveen Kaur
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 30-41 (2023)
Longstanding evidence implicate glioma stem-like cells as the main drivers contributing toward glioblastoma (GBM) therapy resistance and tumor recurrence. Although oncolytic herpes simplex virus (oHSV) viral therapy is a promising biological therapy
Externí odkaz:
https://doaj.org/article/883a24feb9e349a08a398599e2fada98
Autor:
Hussein A. Zeineddine, Bryden H. Dawes, Matthew P. Mullarkey, Juan Carlos Martinez‐Gutierrez, Peng Roc Chen
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 4 (2023)
Cervical vertebral arteriovenous fistula is a rare entity that is typically managed with endovascular techniques. We describe 2 consecutive cases of spontaneous obliteration of high flow cervical vertebral arteriovenous fistulas following angiography
Externí odkaz:
https://doaj.org/article/2194d0a726cb4cb38fc845b57eb07c17
Publikováno v:
Viruses, Vol 14, Iss 1, p 118 (2022)
Oncolytic herpes simplex virus (oHSV) is a highly promising treatment for solid tumors. Intense research and development efforts have led to first-in-class approval for an oHSV for melanoma, but barriers to this promising therapy still exist that lim
Externí odkaz:
https://doaj.org/article/f23593e4a5ef496f90a96734a2aebf14
Publikováno v:
Royal Society Open Science, Vol 2, Iss 12 (2015)
Individual primates can be identified by the sound of their voice. Macaques have demonstrated an ability to discern conspecific identity from a harmonically structured ‘coo’ call. Voice recognition presumably requires the integrated perception of
Externí odkaz:
https://doaj.org/article/63fe7407320f4259b3e317fe230aa835
Autor:
Matthew P, Mullarkey, Hussein A, Zeineddine, Pedram, Honarpishesh, Matthew J, Kole, Joseph, Cochran
Publikováno v:
Journal of Clinical Neuroscience. 106:76-82
In the expanding era of endovascular treatment and minimally invasive techniques, the neurosurgical trainees have a steady decrease in the exposure to microsurgical skills. However, there remain a need for neurosurgical trainees to be proficient at s
Autor:
Bangxing Hong, Upasana Sahu, Matthew P Mullarkey, Evan Hong, Guangsheng Pei, Yuanqing Yan, Yoshihiro Otani, Yeshavanth Banasavadi-Siddegowda, Huihui Fan, Zhongming Zhao, Jianhua Yu, Michael A Caligiuri, Balveen Kaur
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006164
BackgroundMammalian cells have developed multiple intracellular mechanisms to defend against viral infections. These include RNA-activated protein kinase (PKR), cyclic GMP-AMP synthase and stimulation of interferon genes (cGAS-STING) and toll-like re
Autor:
Sara Murphy, Matthew P Mullarkey, Upasana Sahu, Bangxing Hong, Cole Lewis, Miguel Diaz, Pamela Wenzel, Abu Hena Mostafa Kamal, Nagireddy Putluri, Junhyoung Park, Benny Kaipparettu, Balveen Kaur
Publikováno v:
Neuro-Oncology. 24:vii227-vii227
Glioblastoma Multiforme (GBM) is the most aggressive malignant primary brain tumor and has abysmal 5-year overall survival. With the approval of oHSV Imlygic by FDA for metastatic melanoma and more recently, conditional approval of G47Δ, marketed by
Autor:
Upasana Sahu, Matthew P Mullarkey, Evan Hong, Pei Guangsheng, Zhao Zhongming, Bangxing Hong, Balveen Kaur
Publikováno v:
Neuro-Oncology. 24:vii280-vii280
The tumor microenvironment (TME), including the non-tumor cells and the extracellular matrix (ECM) plays a crucial role in tumor progression and metastasis. Hyaluronic acid (HA), the major glycosaminoglycan present in brain ECM, has long been associa
Publikováno v:
Neuro-Oncology. 24:vii220-vii220
Glioblastoma is one of the most lethal and treatment-resistant tumors of the central nervous system. Despite maximal surgical and medical therapy, survival remains dismal with a median of 21 months. Despite advances in treatment, this has only led to
Autor:
Bangxing Hong, Upasana Sahu, Matthew P Mullarkey, Evan Hong, Pei Guangsheng, Yuanqing Yan, Yoshihiro Otani, Huihui Fan, Zhao Zhongming, Balveen Kaur
Publikováno v:
Neuro-Oncology. 24:vii218-vii218
The host immune system has developed many mechanisms to defend against and clear virus infections, including PKR, cGAS-STING and TLR-MyD88 signaling pathways. Compromised anti-viral mechanisms in tumor cells allows for infection, replication and lysi