Výsledky vyhledávání - "Matthew P. McCusker"

Akademický článek

Nano-Strategies to Fight Multidrug Resistant Bacteria—'A Battle of the Titans'

Autor: Pedro V. Baptista, Matthew P. McCusker, Andreia Carvalho, Daniela A. Ferreira, Niamh M. Mohan, Marta Martins, Alexandra R. Fernandes

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Infectious diseases remain one of the leading causes of morbidity and mortality worldwide. The WHO and CDC have expressed serious concern regarding the continued increase in the development of multidrug resistance among bacteria. Therefore, the antib

Externí odkaz: https://doaj.org/article/3cd854d12b07429ebeb18ebef9af2f85

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Akademický článek

Multidrug-Resistant Escherichia coli in Bovine Animals, Europe

Autor: Evan Brennan, Marta Martins, Matthew P. McCusker, Juan Wang, Bruno Martins Alves, Daniel Hurley, Farid El Garch, Frédérique Woehrlé, Christine Miossec, Leisha McGrath, Shabarinath Srikumar, Patrick Wall, Séamus Fanning

Publikováno v: Emerging Infectious Diseases, Vol 22, Iss 9, Pp 1650-1652 (2016)

Of 150 Escherichia coli strains we cultured from specimens taken from cattle in Europe, 3 had elevated MICs against colistin. We assessed all 3 strains for the presence of the plasmid-mediated mcr-1 gene and identified 1 isolate as mcr-1–positive a

Externí odkaz: https://doaj.org/article/a46c1a5fc16a41119eb6baea42c36454

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Akademický článek

The Ins and Outs of RND Efflux Pumps in Escherichia coli

Autor: João eAnes, MATTHEW P. McCUSKER, Seamus eFanning, MARTA eMARTINS

Publikováno v: Frontiers in Microbiology, Vol 6 (2015)

Infectious diseases remain one of the principal causes of morbidity and mortality in the world. Relevant authorities including the WHO and CDC have expressed serious concern regarding the continued increase in the development of multidrug resistance

Externí odkaz: https://doaj.org/article/c5bc0d3f8d9b4c7b927c7678de378f00

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Akademický článek

Salmonella-host interactions - modulation of the host innate immune system

Autor: Daniel eHurley, MATTHEW P. McCUSKER, Seamus eFanning, MARTA eMARTINS

Publikováno v: Frontiers in Immunology, Vol 5 (2014)

Salmonella enterica (S. enterica) are Gram-negative bacteria that can invade a broad range of hosts causing both acute and chronic infections. This phenotype is related to its ability to replicate and persist within non-phagocytic host epithelial cel

Externí odkaz: https://doaj.org/article/aafbbc89d2de4f2282f98acade879e47

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Akademický článek

Complete genome sequence and phenotype microarray analysis of Cronobacter sakazakii SP291: a persistent isolate cultured from a powdered infant formula production facility

Autor: Qiongqiong eYan, Karen A Power, Shane eCooney, Edward eFox, Gopal R. Gopinath, Christopher J. Grim, Ben D. Tall, Matthew P. Mccusker, Seamus eFanning

Publikováno v: Frontiers in Microbiology, Vol 4 (2013)

Outbreaks of human infection linked to the powdered infant formula (PIF) food chain and associated with the bacterium Cronobacter, are of concern to public health. These bacteria are regarded as opportunistic pathogens linked to life-threatening infe

Externí odkaz: https://doaj.org/article/8f964cfcbcde439ca64588c6cb35830e

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Modulation of antimicrobial resistance in clinical isolates of Enterobacter aerogenes: A strategy combining antibiotics and chemosensitisers

Autor: Marta Martins, Matthew P. McCusker, Daniela Alves Ferreira, Séamus Fanning, Bruno Martins Alves, Donal Cooney, Anne Davin-Regli, Jean-Marie Pagès

Publikováno v: Journal of Global Antimicrobial Resistance
Journal of Global Antimicrobial Resistance, Elsevier, 2019, 16, pp.187-198. ⟨10.1016/j.jgar.2018.10.009⟩
Journal of Global Antimicrobial Resistance, 2019, 16, pp.187-198. ⟨10.1016/j.jgar.2018.10.009⟩

Objective The main focus of this study was to evaluate the antimicrobial susceptibility profiles of a number of human clinical isolates of Enterobacter aerogenes isolates and to explore the effects of selected chemosensitisers on reversal of the resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed86ba31020fea4a116c815c80cc886
https://hal-amu.archives-ouvertes.fr/hal-02649582

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Complete genomic sequence analyses of the first group A giraffe rotavirus reveals close evolutionary relationship with rotaviruses infecting other members of the Artiodactyla

Autor: Helen O’Shea, Lynda Gunn, O. Cashman, Marijke E. Beltman, Séamus Fanning, P. J. Collins, Matthew P. McCusker, Emily Mulherin, Jelle Matthijnssens

Publikováno v: Veterinary Microbiology. 170:151-156

Group A Rotaviruses (RVA) have been established as significant contributory agents of acute gastroenteritis in young children and many animal species. In 2008, we described the first RVA strain detected in a giraffe calf (RVA/Giraffe-wt/IRL/GirRV/200

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178374fce6338694f3d047360e6e914e
https://doi.org/10.1016/j.vetmic.2014.01.012

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Evidence of Metabolic Switching and Implications for Food Safety from the Phenome(s) of Salmonella enterica Serovar Typhimurium DT104 Cultured at Selected Points across the Pork Production Food Chain

Autor: Evonne McCabe, Séamus Fanning, Matthew P. McCusker, Denis O'Leary, Geraldine Duffy, Marta Martins

Publikováno v: Applied and Environmental Microbiology. 79:5437-5449

Salmonella enterica serovar Typhimurium DT104 is a recognized food-borne pathogen that displays a multidrug-resistant phenotype and that is associated with systemic infections. At one extreme of the food chain, this bacterium can infect humans, limit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff785abede683854e065e9b8b2d9e3f3
https://doi.org/10.1128/aem.01041-13

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A Simple Method for Assessment of MDR Bacteria for Over-Expressed Efflux Pumps

Autor: Matthew P. McCusker, Miguel Viveiros, Marta Martins, Séamus Fanning, Leonard Amaral, Jean-Marie Pagès, Isabel Couto

Publikováno v: The Open Microbiology Journal
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

It is known that bacteria showing a multi-drug resistance phenotype use several mechanisms to overcome the action of antibiotics. As a result, this phenotype can be a result of several mechanisms or a combination of thereof. The main mechanisms of an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c8314d5ccee70d1254ee7d5030a895
https://doi.org/10.2174/1874285801307010072

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Alternative Therapeutics against MDR Bacteria – 'Fighting the Epidemic of Antibiotic Resistance'

Autor: Matthew P. McCusker, Marta Martins

Publikováno v: Articles
Frontiers in Microbiology

The introduction of the first antibiotic, followed by the “golden age” of antibiotic discovery was expected to herald the end of infectious diseases. However, microbial evolution in response to antibiotic selection pressure has ended that expecta

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