Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Matthew P, Morrow"'
Autor:
Laurent Humeau, David Weiner, Robert H Vonderheide, Matthew P Morrow, Trevor McMullan, Anthony F Shields, Ashish V Chintakuntlawar, Kimberly A Kraynyak, Autumn J McRee, Jennifer M Johnson, Weijing Sun, Jan Pawlicki, Albert J Sylvester, Robert Samuels, Joseph J Kim, Jean D Boyer, Jeffrey M Skolnik
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Human telomerase reverse transcriptase (hTERT) is frequently classified as a ‘universal’ tumor associated antigen due to its expression in a vast number of cancers. We evaluated plasmid DNA-encoded hTERT as an immunotherapy across nine
Externí odkaz:
https://doaj.org/article/a019d7273be04e4cbb43557f12c156de
Autor:
Pablo Tebas, ShuPing Yang, Jean D. Boyer, Emma L. Reuschel, Ami Patel, Aaron Christensen-Quick, Viviane M. Andrade, Matthew P. Morrow, Kimberly Kraynyak, Joseph Agnes, Mansi Purwar, Albert Sylvester, Jan Pawlicki, Elisabeth Gillespie, Igor Maricic, Faraz I. Zaidi, Kevin Y. Kim, Yaya Dia, Drew Frase, Patrick Pezzoli, Katherine Schultheis, Trevor R.F. Smith, Stephanie J. Ramos, Trevor McMullan, Karen Buttigieg, Miles W. Carroll, John Ervin, Malissa C. Diehl, Elliott Blackwood, Mammen P. Mammen, Jessica Lee, Michael J. Dallas, Ami Shah Brown, Jacqueline E. Shea, J.Joseph Kim, David B. Weiner, Kate E. Broderick, Laurent M. Humeau
Publikováno v:
EClinicalMedicine, Vol 31, Iss , Pp 100689- (2021)
Background: A vaccine against SARS-CoV-2 is of high urgency. Here the safety and immunogenicity induced by a DNA vaccine (INO-4800) targeting the full length spike antigen of SARS-CoV-2 are described. Methods: INO-4800 was evaluated in two groups of
Externí odkaz:
https://doaj.org/article/a9f1cb97a12243469984e15dede48ebe
Autor:
Jeffrey M, Jacobson, David, Zahrieh, Carrie A, Strand, Marcia, Cruz-Correa, Surakit, Pungpapong, Lewis R, Roberts, Sumithra J, Mandrekar, Luz María, Rodriguez, Jean, Boyer, Idania, Marrero, Kimberly A, Kraynyak, Matthew P, Morrow, Albert J, Sylvester, Jan M, Pawlicki, Elisabeth, Gillespie, Eduardo, Barranco, Ellen, Richmond, Asad, Umar, David B, Weiner, Paul J, Limburg
Publikováno v:
Cancer Prevention Research. 16:163-173
Chronic hepatitis C can lead to cirrhosis and hepatocellular carcinoma. We studied the safety and immunogenicity of a novel therapeutic hepatitis C virus (HCV) genotype 1a/1b consensus DNA vaccine, INO-8000, encoding HCV NS3, NS4A, NS4B, and NS5A pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22816b511314916d704c305f6aca562
https://doi.org/10.1158/1940-6207.capr-22-0217
https://doi.org/10.1158/1940-6207.capr-22-0217
Autor:
Ted Mau, Milan R. Amin, Peter C. Belafsky, Simon R. Best, Aaron D. Friedman, Adam M. Klein, David G. Lott, Randal C. Paniello, Seth M. Pransky, Nabil F. Saba, Tamara Howard, Michael Dallas, Aditya Patel, Matthew P. Morrow, Jeffrey M. Skolnik
Publikováno v:
The Laryngoscope.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77c9efc7023a2515f06d460f62bcb572
https://doi.org/10.1002/lary.30749
https://doi.org/10.1002/lary.30749
Autor:
Mark L. Bagarazzi, Cornelia L. Trimble, David B. Weiner, Stanley Plotkin, J. Joseph Kim, Niranjan Y. Sardesai, Laurent Humeau, Amir S. Khan, Russell Vang, Jian Yan, Jean D. Boyer, Dawson Knoblock, Michael Dallas, Albert J. Sylvester, Kimberly A. Kraynyak, Matthew P. Morrow
Supplemental Figure 1 - Rates of CIN2/3 regression (primary endpoint) or CIN2/3 regression concomitant with clearance of HPV16 and/or HPV18 infection (secondary endpoint) in the Per Protocol population of the Phase IIb study of VGX-3100 for the treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aba4a17eb58c63a1341c4b673bd3881
https://doi.org/10.1158/1078-0432.22467135.v1
https://doi.org/10.1158/1078-0432.22467135.v1
Autor:
Mark L. Bagarazzi, Cornelia L. Trimble, David B. Weiner, Stanley Plotkin, J. Joseph Kim, Niranjan Y. Sardesai, Laurent Humeau, Amir S. Khan, Russell Vang, Jian Yan, Jean D. Boyer, Dawson Knoblock, Michael Dallas, Albert J. Sylvester, Kimberly A. Kraynyak, Matthew P. Morrow
Purpose: As previously reported, treatment of high-grade cervical dysplasia with VGX-3100 resulted in complete histopathologic regression (CR) concomitant with elimination of HPV16/18 infection in 40.0% of VGX-3100–treated patients compared with on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b28af5e03ba2006f897889071c16ba8
https://doi.org/10.1158/1078-0432.c.6526548.v1
https://doi.org/10.1158/1078-0432.c.6526548.v1
Autor:
Mark L. Bagarazzi, Ildiko Csiki, David Weiner, Rakesh Kumar, Mark Esser, Susan Duff, Sandra Oyola, Michael Dallas, Russell Vang, Drishty Mangrolia, Kelsie Dickerson, Aubrey Anton, Sophie Tan, Lindsay Sakata, Jean Boyer, Alexander Lin, Gregory S. Weinstein, Joshua M. Bauml, Dawson M. Knoblock, Albert J. Sylvester, Kimberly A. Kraynyak, Matthew P. Morrow, Roger B. Cohen, Charu Aggarwal
Supplemental Table 2: Number of patients in each cohort with any seroreactivity against the candidate antigens (HPV 16,18 E6 and E7) at (A) any timepoint following vaccination and (B) three months following final vaccination Supplemental Table 3: Flo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eabed1abfd4b80f484b655c53dec8d
https://doi.org/10.1158/1078-0432.22472916.v1
https://doi.org/10.1158/1078-0432.22472916.v1
Autor:
Mark L. Bagarazzi, Ildiko Csiki, David Weiner, Rakesh Kumar, Mark Esser, Susan Duff, Sandra Oyola, Michael Dallas, Russell Vang, Drishty Mangrolia, Kelsie Dickerson, Aubrey Anton, Sophie Tan, Lindsay Sakata, Jean Boyer, Alexander Lin, Gregory S. Weinstein, Joshua M. Bauml, Dawson M. Knoblock, Albert J. Sylvester, Kimberly A. Kraynyak, Matthew P. Morrow, Roger B. Cohen, Charu Aggarwal
Purpose:Clinical responses with programmed death (PD-1) receptor–directed antibodies occur in about 20% of patients with advanced head and neck squamous cell cancer (HNSCCa). Viral neoantigens, such as the E6/E7 proteins of HPV16/18, are attractive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6796bfeadb07acc04de8d95a04654454
https://doi.org/10.1158/1078-0432.c.6528372
https://doi.org/10.1158/1078-0432.c.6528372
Autor:
Mark L. Bagarazzi, Cornelia L. Trimble, David B. Weiner, Stanley Plotkin, J. Joseph Kim, Niranjan Y. Sardesai, Laurent Humeau, Amir S. Khan, Russell Vang, Jian Yan, Jean D. Boyer, Dawson Knoblock, Michael Dallas, Albert J. Sylvester, Kimberly A. Kraynyak, Matthew P. Morrow
Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781222e7481bb332437ebd226d7503f2
https://doi.org/10.1158/1078-0432.22467138
https://doi.org/10.1158/1078-0432.22467138
Autor:
Mark L. Bagarazzi, Ildiko Csiki, David Weiner, Rakesh Kumar, Mark Esser, Susan Duff, Sandra Oyola, Michael Dallas, Russell Vang, Drishty Mangrolia, Kelsie Dickerson, Aubrey Anton, Sophie Tan, Lindsay Sakata, Jean Boyer, Alexander Lin, Gregory S. Weinstein, Joshua M. Bauml, Dawson M. Knoblock, Albert J. Sylvester, Kimberly A. Kraynyak, Matthew P. Morrow, Roger B. Cohen, Charu Aggarwal
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51803170b0d9f9397e5106bcc930d031
https://doi.org/10.1158/1078-0432.22472922.v1
https://doi.org/10.1158/1078-0432.22472922.v1