Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthew N McCarroll"'
Autor:
Matthew N McCarroll, Alex V Nechiporuk
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85087 (2013)
Essential cellular components of the paired sensory organs of the vertebrate head are derived from transient thickenings of embryonic ectoderm known as cranial placodes. The epibranchial (EB) placodes give rise to sensory neurons of the EB ganglia th
Externí odkaz:
https://doaj.org/article/3b9f383b1cac40b2b7c38b77c7684831
Autor:
Bin Yang, Merlin Lange, Alfred Millett-Sikking, Xiang Zhao, Jordão Bragantini, Shruthi VijayKumar, Mason Kamb, Rafael Gómez-Sjöberg, Ahmet Can Solak, Wanpeng Wang, Hirofumi Kobayashi, Matthew N. McCarroll, Lachlan W. Whitehead, Reto P. Fiolka, Thomas B. Kornberg, Andrew G. York, Loic A. Royer
Publikováno v:
Nature Methods. 19:461-469
The promise of single-objective light-sheet microscopy is to combine the convenience of standard single-objective microscopes with the speed, coverage, resolution and gentleness of light-sheet microscopes. We present DaXi, a single-objective light-sh
Autor:
Siwen Wang, Zhonghan Li, Desiree Aispuro, Nathan Guevara, Juno Van Valkenburgh, Boxi Chen, Xiaoyun Zhou, Matthew N. McCarroll, Fei Ji, Xu Cong, Priyanka Sarkar, Rohit Chaudhuri, Zhili Guo, Nicole P. Perkins, Shiqun Shao, Jason K. Sello, Kai Chen, Min Xue
Publikováno v:
Journal of the American Chemical Society, vol 144, iss 44
Delivering cargo molecules across the plasma membrane is critical for biomedical research, and the need to develop molecularly well-defined tags that enable cargo transportation is ever-increasing. We report here a hydrophilic endocytosis-promoting p
Autor:
Bin, Yang, Merlin, Lange, Alfred, Millett-Sikking, Xiang, Zhao, Jordão, Bragantini, Shruthi, VijayKumar, Mason, Kamb, Rafael, Gómez-Sjöberg, Ahmet Can, Solak, Wanpeng, Wang, Hirofumi, Kobayashi, Matthew N, McCarroll, Lachlan W, Whitehead, Reto P, Fiolka, Thomas B, Kornberg, Andrew G, York, Loic A, Royer
Publikováno v:
Nature methods. 19(4)
The promise of single-objective light-sheet microscopy is to combine the convenience of standard single-objective microscopes with the speed, coverage, resolution and gentleness of light-sheet microscopes. We present DaXi, a single-objective light-sh
Autor:
Lindsay P. Cameron, Douglas Myers-Turnbull, Jayashri Viswanathan, Oliver Fiehn, Zachary Rabow, Guoliang Zhang, David E. Olson, Bianca Yaghoobi, Zefan Q. Hurley, Brandon M. Brown, Jamie Peters, David Kokel, Maxemiliano V. Vargas, Robert J. Tombari, Lauren J. Laskowski, Matthew N. McCarroll, John D. McCorvy, Alexander J. Pell, Taohui Liu, Pamela J. Lein, Jack C. Taylor, Yi Zuo, Ju Lu, Yann Ehinger, Michelle Tjia, Heike Wulff, Emilie I. Anderson, Lee E. Dunlap, Dorit Ron
Publikováno v:
Nature, vol 589, iss 7842
Nature
Nature
The psychedelic alkaloid ibogaine has anti-addictive properties in both humans and animals1. Unlike most medications for the treatment of substance use disorders, anecdotal reports suggest that ibogaine has the potential to treat addiction to various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac37c443462daef2d948da379f29fb96
https://escholarship.org/uc/item/5pp1d1vm
https://escholarship.org/uc/item/5pp1d1vm
Autor:
Merlin Lange, Reto Fiolka, Lachlan Whitehead, Bin Yang, Ahmet Can Solak, Andrew York, Matthew N McCarroll, Hirofumi Kobayashi, Loic Royer, Wanpeng Wang, Shruthi Vijay Kumar, Alfred Millett-Sikking, Thomas B. Kornberg
Recent developments in Oblique Plane Microscopy (OPM) have shown that it can achieve high spatio-temporal resolution. Here we describe a single objective light-sheet microscope based on oblique plane illumination that achieves: (i) large field of vie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3a5ce952b63896a28848476eb795f87
https://doi.org/10.1101/2020.09.22.309229
https://doi.org/10.1101/2020.09.22.309229
TRPA1 receptors sense chemical irritants, but they do not normally respond to light. Previous studies have identified compounds that confer photosensitivity onto vertebrate TRPA1. However, the pharmacology of TRPA1-mediated non-visual photosensation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1fc551743cdf36c6b1d3a89f850b1ef
https://doi.org/10.1101/2020.06.10.111203
https://doi.org/10.1101/2020.06.10.111203
Autor:
Douglas Myers-Turnbull, Jack C Taylor, Cole Helsell, Matthew N McCarroll, Chris S Ki, Tia A Tummino, Shreya Ravikumar, Reid Kinser, Leo Gendelev, Rebekah Alexander, Michael J Keiser, David Kokel
Purpose Compounds that act on the central nervous system (CNS) are crucial tools in drug discovery and neuroscience. To discover compounds with novel mechanisms of action, researchers have developed behavioral screens in larval zebrafish including va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9d38f3ac1518d69a76453d0973bde61
https://doi.org/10.1101/2020.01.01.891432
https://doi.org/10.1101/2020.01.01.891432
Autor:
Capria Rinaldi, Leo Gendelev, Randall T. Peterson, Reid Kinser, Cole Helsell, Giancarlo N. Bruni, Jack C. Taylor, Matthew N. McCarroll, Amanda Carbajal, Jung Ho Gong, Douglas Myers-Turnbull, Jason K. Sello, David Kokel, Hye Jin Kang, Michael J. Keiser, Susumu Tomita
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Anesthetics are generally associated with sedation, but some anesthetics can also increase brain and motor activity—a phenomenon known as paradoxical excitation. Previous studies have identified GABAA receptors as the primary targets of most anesth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cc30638eaa09534fd1afd3af00f04d
https://escholarship.org/uc/item/8vz8j9rq
https://escholarship.org/uc/item/8vz8j9rq
Publikováno v:
ACS chemical biology, vol 11, iss 4
Many psychiatric drugs modulate the nervous system through multi-target mechanisms. However, systematic identification of multi-target compounds has been difficult using traditional in vitro screening assays. New approaches to phenotypic profiling in