Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Matthew M. Yeh"'
Autor:
Hung-Wen Tsai, Chien-Yu Chiou, Wei-Jong Yang, Tsan-An Hsieh, Cheng-Yi Chen, Che-Wei Hsu, Yih-Jyh Lin, Min-En Hsieh, Matthew M. Yeh, Chin-Chun Chen, Meng-Ru Shen, Pau-Choo Chung
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 261-270 (2024)
Goal: The early diagnosis and treatment of hepatitis is essential to reduce hepatitis-related liver function deterioration and mortality. One component of the widely-used Ishak grading system for the grading of periportal interface hepatitis is based
Externí odkaz:
https://doaj.org/article/39b885ccbc2b47bab366ff030aa2c10c
Autor:
Yongjun Liu, David P. Al‐Adra, Ruoxin Lan, Geunyoung Jung, Huihua Li, Matthew M. Yeh, Yao‐Zhong Liu
Publikováno v:
Hepatology Communications, Vol 6, Iss 8, Pp 2170-2181 (2022)
Abstract Dysregulation of expression of functional genes and pathways plays critical roles in the etiology and progression of hepatocellular carcinoma (HCC). Next generation‐based RNA sequencing (RNA‐seq) offers unparalleled power to comprehensiv
Externí odkaz:
https://doaj.org/article/62e249f9781c40558a28590a568cc0d5
Autor:
George N. Ioannou, Christian L. Horn, Vishal Kothari, Matthew M. Yeh, Irene Shyu, Sum P. Lee, Christopher E. Savard
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100330- (2023)
It has been postulated that inflammasomes, in particular the NLRP3 (NLR family pyrin domain containing 3) inflammasome, mediate the necroinflammation and fibrosis that characterize nonalcoholic steatohepatitis (NASH) by engaging innate immune respons
Externí odkaz:
https://doaj.org/article/47d6015b513c4fc0926ba16b50728c65
Autor:
George N. Ioannou, Sum P. Lee, Peter S. Linsley, Vivian Gersuk, Matthew M. Yeh, Yen‐Ying Chen, Yi‐Jen Peng, Moumita Dutta, Gabby Mascarinas, Bruk Molla, Julia Yue Cui, Christopher Savard
Publikováno v:
Hepatology Communications, Vol 6, Iss 4, Pp 780-794 (2022)
Proprotein convertase subtilisin/kexin type 9 (Pcsk9) binds to hepatic low‐density lipoprotein receptor (LDLR) and induces its internalization and degradation. Pcsk9 inhibition increases LDLR expression by hepatocytes, which causes increased uptake
Externí odkaz:
https://doaj.org/article/ef686476bec244748709ac6cd63fc5bf
Autor:
Yen-Ying Chen, Matthew M. Yeh
Publikováno v:
Journal of the Formosan Medical Association, Vol 120, Iss 1, Pp 68-77 (2021)
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in North America and Europe, with increasing prevalence in other regions of the world. Its spectrum encompass steatosis, non-alcoholic steatohepatitis (NASH), fibrosis
Externí odkaz:
https://doaj.org/article/0c4672ea35d64a92bb5eaee49e5249ff
Publikováno v:
Gut and Liver, Vol 13, Iss 6, Pp 596-603 (2019)
Gastric intestinal metaplasia (GIM) is a known premalignant condition of the human stomach along the pathway to gastric cancer (GC). Histologically, GIM represents the replacement of normal gastric mucosa by mucin-secreting intestinal mucosa. Helicob
Externí odkaz:
https://doaj.org/article/457a84cfc32640799d3ba034c0e90725
Autor:
Jessie Qiaoyi Liang, Narcissus Teoh, Lixia Xu, Sharon Pok, Xiangchun Li, Eagle S. H. Chu, Jonathan Chiu, Ling Dong, Evi Arfianti, W. Geoffrey Haigh, Matthew M. Yeh, George N. Ioannou, Joseph J. Y. Sung, Geoffrey Farrell, Jun Yu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nonalcoholic steatohepatitis (NASH) and dietary cholesterol are risk factors for hepatocellular carcinoma (HCC). Here, the authors utilise mouse models to show that dietary cholesterol induces NASH by deregulating genes involved in metabolism, inflam
Externí odkaz:
https://doaj.org/article/f586a8b5cf4f4dbbb56141228ef1c3be
Autor:
Joseph R. Roberts, MD, Konstantin Koro, MD, Matthew M. Yeh, MD, PhD, Michael D. Saunders, MD, Adam W. Templeton, MD
Publikováno v:
VideoGIE, Vol 3, Iss 8, Pp 244-246 (2018)
Externí odkaz:
https://doaj.org/article/d1155aee6e934d17b49d3a415da08df8
Autor:
George N. Ioannou, Savitha Subramanian, Alan Chait, W. Geoffrey Haigh, Matthew M. Yeh, Geoffrey C. Farrell, Sum P. Lee, Christopher Savard
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1067-1079 (2017)
We recently reported that cholesterol crystals form in hepatocyte lipid droplets (LDs) in human and experimental nonalcoholic steatohepatitis. Herein, we assigned WT C57BL/6J mice to a high-fat (15%) diet for 6 months, supplemented with 0%, 0.25%, 0.
Externí odkaz:
https://doaj.org/article/64140dc3cc9a4d47bcb07f51a58c9e39
Autor:
Priya Handa, Bryan D. Maliken, James E. Nelson, Kelly A. Hennessey, L. Akhila Vemulakonda, Vicki Morgan-Stevenson, Barjinder K. Dhillon, Rohit Gupta, Matthew M. Yeh, Kris V. Kowdley
Publikováno v:
Annals of Hepatology, Vol 16, Iss 1, Pp 77-85 (2017)
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. We have previously shown that hepatic reticuloendothelial system (RES) iron deposition is associated with an advanced degree of nonalcoholic steatoh
Externí odkaz:
https://doaj.org/article/6bf710d62f12440ca5d8fc93b424908c