Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Matthew M. Ford"'
Autor:
Colleen A. Mangold, Benjamin Wronowski, Mei Du, Dustin R. Masser, Niran Hadad, Georgina V. Bixler, Robert M. Brucklacher, Matthew M. Ford, William E. Sonntag, Willard M. Freeman
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-19 (2017)
Abstract Background The necessity of including both males and females in molecular neuroscience research is now well understood. However, there is relatively limited basic biological data on brain sex differences across the lifespan despite the diffe
Externí odkaz:
https://doaj.org/article/8ff50482fdfc4d15be815b02c6ed9c50
Autor:
Matthew M. Ford, Xiaojie Wang, Colin Studholme, Christopher D. Kroenke, Natali Newman, Verginia C. Cuzon Carlson, Kathleen A. Grant
Publikováno v:
Proc Natl Acad Sci U S A
One factor that contributes to the high prevalence of fetal alcohol spectrum disorder (FASD) is binge-like consumption of alcohol before pregnancy awareness. It is known that treatments are more effective with early recognition of FASD. Recent advanc
Autor:
Rita Cervera-Juanes, Houda Mesnaoui, Carlos F. Aylwin, Matthew M. Ford, Alejandro Lomniczi, Verginia C. Cuzon Carlson, Betsy Ferguson, Timothy L. Carlson
Publikováno v:
Addict Biol
Hazardous, heavy drinking increases risk for developing alcohol use disorder (AUD), which affects ~ 7% of adult Americans. Thus understanding the molecular mechanisms promoting risk for heavy drinking is essential to developing more effective AUD pha
Autor:
Cara Stull, Kathleen A. Grant, Matthew M. Ford, Brandy L. Dozier, Jeremiah P. Jensen, Erich J. Baker, Deborah A. Finn
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Sporadic reports of alcohol consumption being linked to menstrual cycle phase highlight the need to consider hormonally-characterized menstrual cycle phase in understanding the sex-specific effects of risk for alcohol drinking in women. OB
Autor:
Alejandro Lomniczi, Kathleen A. Grant, Matthew M. Ford, Betsy Ferguson, Timothy L. Carlson, Verginia C. Cuzon Carlson, Rita Cervera-Juanes
Publikováno v:
Neuropsychopharmacology
Alcohol use disorder (AUD) is a chronic condition with devastating health and socioeconomic effects. Still, pharmacotherapies to treat AUD are scarce. In a prior study aimed at identifying novel AUD therapeutic targets, we investigated the DNA methyl
Autor:
Matthew M. Ford, Jeremiah P. Jensen, Deborah A. Finn, John C. Crabbe, David J. Rossi, Michelle A. Nipper, Melinda L. Helms
Publikováno v:
Neuroscience. 397:127-137
Sensitivity to anticonvulsant effects of the γ-aminobutyric acid(A) receptor-active neurosteroid allopregnanolone (ALLO) during ethanol withdrawal varies across genotypes, with high sensitivity in genotypes with mild withdrawal and low sensitivity i
Publikováno v:
The FASEB Journal. 35
Autor:
Dustin R. Masser, Matthew M. Ford, Aditya Pisupati, David R. Stanford, Cory B. Giles, William E. Sonntag, Colleen A. Mangold, Georgina V. Bixler, Jonathan D. Wren, Willard M. Freeman
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 72:16-29
The major histocompatibility complex I (MHCI) pathway, which canonically functions in innate immune viral antigen presentation and detection, is functionally pleiotropic in the central nervous system (CNS). Alternative roles include developmental syn
Autor:
Matthew M. Ford, Alexander Kuryatov, Kathleen A. Grant, Eliot R. Spindel, Jon Lindstrom, Daicia C. Allen, Lyndsey E. Shorey-Kendrick, Larry J. Wilhelm
Publikováno v:
Neuropharmacology
Nicotinic acetylcholine receptors (nAChRs) are highly conserved between humans and non-human primates. Conservation exists at the level of genomic structure, protein structure and epigenetics. Overall homology of nAChRs at the protein level is 98% in
Autor:
Arlan Richardson, Mikhail G. Dozmorov, Dustin R. Masser, Hunter Porter, Jonathan D. Wren, Matthew M. Ford, Niran Hadad, David R. Stanford, Cory B. Giles, Colleen A. Mangold, Willard M. Freeman, Archana Unnikrishnan, Constantin Georgescu
Publikováno v:
Aging Cell
Summary DNA methylation is a central regulator of genome function, and altered methylation patterns are indicative of biological aging and mortality. Age‐related cellular, biochemical, and molecular changes in the hippocampus lead to cognitive impa