Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Matthew M. Dedek"'
Autor:
Victor J. Hruby, Bahar Tan, Minying Cai, Alexander V. Mayorov, James P. Cain, Erin S. Palmer, Matthew M. Dedek, Dev Trivedi, Dustin K. Tanaka
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:3099-3102
A novel hybrid melanocortin pharmacophore was designed based on the topographical similarities between the pharmacophores of Agouti related protein (AGRP) an endogenous melanocortin antagonist, and α-melanocyte-stimulating hormone (α-MSH), an endog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bc881439fa48b9cbe5ea551c4310cc
https://doi.org/10.1016/j.bmcl.2011.03.019
https://doi.org/10.1016/j.bmcl.2011.03.019
Autor:
Matthew M. Dedek, Minying Cai, Josef Vagner, Erin S. Palmer, Bahar Tan, April R. Van Scoy, James P. Cain, Victor J. Hruby, Alexander V. Mayorov, Dev Trivedi
Publikováno v:
Journal of Medicinal Chemistry. 51:187-195
A variety of dicarboxylic acid linkers introduced between the alpha-amino group of Pro(6) and the -amino group of Lys(10) of the cyclic lactam alpha-melanocyte-stimulating hormone (alpha-MSH)-derived Pro(6)-D-Phe(7)/D-Nal(2')(7)-Arg(8)-Trp(9)-Lys(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6fcea9b8832c048124f399df5de4aa
https://doi.org/10.1021/jm070461w
https://doi.org/10.1021/jm070461w
Autor:
null Matthew M. Dedek, null Devendra Trivedi, null James P. Cain, null Minying Cai, null Victor J. Hruby
Publikováno v:
Current Topics in Medicinal Chemistry. 7:1085-1097
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::563a38d3cea4f79a38a50300dcf32c5c
https://doi.org/10.2174/156802607780906654
https://doi.org/10.2174/156802607780906654
Autor:
James P. Cain, Alexander V. Mayorov, Victor J. Hruby, Minying Cai, D. Trivedi, Matthew M. Dedek
The processed products of the proopiomelanocortin gene (ACTH, alpha-MSH, beta-MSH, gamma-MSH, etc.) interact with five melanocortin receptors, the MC1R, MC2R, MC3R, MC4R, and MC5R to modulate and control many important biological functions crucial fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf24732b1d7d3c28e3d8cf68635c77c
https://europepmc.org/articles/PMC2274922/
https://europepmc.org/articles/PMC2274922/
Autor:
Minying Cai, Josef Vagner, Xuyuan Gu, Dev Trivedi, Victor J. Hruby, Matthew M. Dedek, Jinfa Ying
Publikováno v:
Journal of medicinal chemistry. 49(23)
Intensive efforts have been made to develop potent and selective ligands for certain human melanocortin receptors as possible treatments for obesity and sexual dysfunction due to the role of these receptors in feeding behavior, energy homeostasis, se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e84895264934974a6b431ff2496c53
https://pubmed.ncbi.nlm.nih.gov/17154518
https://pubmed.ncbi.nlm.nih.gov/17154518
Autor:
Alexander V. Mayorov, Minying Cai, Erin S. Palmer, Matthew M. Dedek, James P. Cain, April R. Van Scoy, Bahar Tan, Josef Vagner, Dev Trivedi, Victor J. Hruby
Publikováno v:
Journal of Medicinal Chemistry; Dec2007, Vol. 51 Issue 2, p187-195, 9p
Autor:
Xi, Ning
Publikováno v:
Current Topics in Medicinal Chemistry; June 2007, Vol. 7 Issue: 11 p1040-1041, 2p