Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Matthew M. Crane"'
Autor:
Matthew M. Crane, Mitsuhiro Tsuchiya, Ben W. Blue, Jared D. Almazan, Kenneth L. Chen, Siobhan R. Duffy, Alexandra Golubeva, Annaiz M. Grimm, Alison M. Guard, Shauna A. Hill, Ellen Huynh, Ryan M. Kelly, Michael Kiflezghi, Hyunsung D. Kim, Mitchell Lee, Ting-I. Lee, Jiayi Li, Bao M.G. Nguyen, Riley M. Whalen, Feng Y. Yeh, Mark McCormick, Brian K. Kennedy, Joe R. Delaney, Matt Kaeberlein
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss , Pp 104-108 (2019)
An increase in cell size with age is a characteristic feature of replicative aging in budding yeast. Deletion of the gene encoding Whi5 results in shortened duration of G1 and reduced cell size, and has been previously suggested to increase replicati
Externí odkaz:
https://doaj.org/article/c89ce9517266486f955ce79743486c70
Autor:
Kenneth L. Chen, Toby N. Ven, Matthew M. Crane, Dexter E. Chen, Yen-Chi Feng, Nozomi Suzuki, Adam E. Russell, Diogo de Moraes, Matt Kaeberlein
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss , Pp 52-56 (2019)
Recently, microfluidic technologies have been developed to allow higher throughput collection of yeast replicative lifespan data. Adoption of these devices has been limited, in part, due to the high cost of the motorized microscopy instrumentation fr
Externí odkaz:
https://doaj.org/article/d581a5beefe545e9aa0b3ffef2386942
Autor:
Bryan Sands, Nikolay Burnaevskiy, Soo R. Yun, Matthew M. Crane, Matt Kaeberlein, Alexander Mendenhall
Publikováno v:
Translational Medicine of Aging, Vol 2, Iss , Pp 1-10 (2018)
One way scientists can observe and quantify processes in living cells is to engineer the genomes of animals to express multiple fluorescent proteins and then quantify those signals by various imaging techniques. To allow our laboratories to confident
Externí odkaz:
https://doaj.org/article/069145c92079481f9a1b8a182e305448
Autor:
Adriana San-Miguel, Peri T. Kurshan, Matthew M. Crane, Yuehui Zhao, Patrick T. McGrath, Kang Shen, Hang Lu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Experimenter scoring of cellular imaging data can be biased. This study describes an automated and unbiased multidimensional phenotyping method that relies on machine learning and complex feature computation of imaging data, and identifies weak allel
Externí odkaz:
https://doaj.org/article/03b8216cade54677a546756f6c9445f4
Autor:
Robin W. Klemm, Justin P. Norton, Ronald A. Cole, Chen S. Li, Seong H. Park, Matthew M. Crane, Liying Li, Diana Jin, Alexandra Boye-Doe, Tina Y. Liu, Yoko Shibata, Hang Lu, Tom A. Rapoport, Robert V. Farese, Jr., Craig Blackstone, Yi Guo, Ho Yi Mak
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1465-1475 (2013)
Lipid droplets (LDs) are the major fat storage organelles in eukaryotic cells, but how their size is regulated is unknown. Using genetic screens in C. elegans for LD morphology defects in intestinal cells, we found that mutations in atlastin, a GTPas
Externí odkaz:
https://doaj.org/article/70257a33a26343e89708a3a6891a3693
Autor:
David J Thaller, Matt Kaeberlein, C. Patrick Lusk, Owen T Terpstra, Sara N. Mouton, Arnold J. Boersma, Matthew M. Crane, Liesbeth M. Veenhoff, Anton Steen, Irina L Rempel
Publikováno v:
eLife, 9:54707, 1-23. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 9 (2020)
eLife
eLife, Vol 9 (2020)
eLife
Cellular aging is a multifactorial process that is characterized by a decline in homeostatic capacity, best described at the molecular level. Physicochemical properties such as pH and macromolecular crowding are essential to all molecular processes i
Autor:
Hyunsung D. Kim, Michael G. Kiflezghi, Ting-I Lee, Ryan M. Kelly, Jared Almazan, Mitchell B. Lee, Siobhan R. Duffy, Shauna A. Hill, Riley Whalen, Feng Y. Yeh, Ellen Huynh, Mitsuhiro Tsuchiya, Bao M.G. Nguyen, Ken Chen, Brian K. Kennedy, Annaiz M. Grimm, Matt Kaeberlein, Joe R. Delaney, Mark A. McCormick, Matthew M. Crane, Ben W. Blue, Jiayi Li, Alison M. Guard, Alexandra Golubeva
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss, Pp 104-108 (2019)
An increase in cell size with age is a characteristic feature of replicative aging in budding yeast. Deletion of the gene encoding Whi5 results in shortened duration of G1 and reduced cell size, and has been previously suggested to increase replicati
Autor:
Diogo de Moraes, Nozomi Suzuki, Ken Chen, Dexter E. Chen, Matt Kaeberlein, Matthew M. Crane, Toby N. Ven, Yen-Chi Feng, Adam E Russell
Publikováno v:
Translational medicine of aging
Translational Medicine of Aging, Vol 3, Iss, Pp 52-56 (2019)
Translational Medicine of Aging, Vol 3, Iss, Pp 52-56 (2019)
Recently, microfluidic technologies have been developed to allow higher throughput collection of yeast replicative lifespan data. Adoption of these devices has been limited, in part, due to the high cost of the motorized microscopy instrumentation fr
Autor:
Sara N Mouton, David J Thaller, Matthew M Crane, Irina L Rempel, Owen T Terpstra, Anton Steen, Matt Kaeberlein, C Patrick Lusk, Arnold J Boersma, Liesbeth M Veenhoff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e32374c74afc99e29945ab9d7da629
https://doi.org/10.7554/elife.54707.sa2
https://doi.org/10.7554/elife.54707.sa2
Autor:
Arjun Dulal, Alex T. Gong, Matthew M. Crane, Troy E. Reihsen, Robert M. Sweet, Alexander Mendenhall
Our research is focused on creating and simulating hyper-realistic artificial human tissue analogues. Generation and simulation of macroscopic biological material depends upon accurate ground-truth data on spectral properties of materials. Here, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8868a7c124071a0161f6890f0b07d85e
https://doi.org/10.1101/2020.02.25.964924
https://doi.org/10.1101/2020.02.25.964924