Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Matthew M Hurley"'
Autor:
Gregory Simand, Gregory J. Simand, Evan Hess, Linghai Kong, Nicholas J. Raddatz, Matthew M Hurley, Brian Maunze, SuJean Choi, Aron M. Geurts, David A. Baker
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 76-76 (2022)
OBJECTIVES/GOALS: We aim to determine whether non-neuronal, non-synaptic glutamate signaling mechanisms can be targeted to produce highly specific, narrow changes in brain function that would benefit CNS disorders. To do this, we investigated cogniti
Externí odkaz:
https://doaj.org/article/f0d5bc85c7a9421885ab6fab76126b3b
An evolutionary and cognitive account of the addictive mind candy that is humor.Some things are funny—jokes, puns, sitcoms, Charlie Chaplin, The Far Side, Malvolio with his yellow garters crossed—but why? Why does humor exist in the first place?
Autor:
Evan M. Hess, Sara N. Kassel, Gregory Simandl, Nicholas Raddatz, Brian Maunze, Matthew M. Hurley, Michael Grzybowski, Jason Klotz, Aron Geurts, Qing-Song Liu, SuJean Choi, Robert C. Twining, David A. Baker
Publikováno v:
The Journal of Neuroscience. 43:2349-2361
The importance of neuronal glutamate to synaptic transmission throughout the brain illustrates the immense therapeutic potential and safety risks of targeting this system. Astrocytes also release glutamate, the clinical relevance of which is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0f13b5b3165b41660ba3aa7a247cb6
https://doi.org/10.1523/jneurosci.1525-22.2023
https://doi.org/10.1523/jneurosci.1525-22.2023
Autor:
Adriano Dellapolla, Ian Kloehn, Harshida Pancholi, Ben Callif, David Wertz, Kayla E. Rohr, Matthew M. Hurley, Kimberly M. Baker, Samer Hattar, Marieke R. Gilmartin, Jennifer A. Evans
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Light improves cognitive function in humans; however, the neurobiological mechanisms underlying positive effects of light remain unclear. One obstacle is that most rodent models have employed lighting conditions that cause cognitive deficits
Externí odkaz:
https://doaj.org/article/933aa58583174768b0ff8c9ff02dcc4b
Autor:
Matthew M. Hurley, Kimberly R. Smith, Civonnia Harris, Ethan J. Goodman, Susan Carnell, Vidyulata Kamath, Timothy H. Moran, Kimberley E. Steele
Publikováno v:
International Journal of Obesity. 46:2114-2119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e8edde9cf8a6a9a45fe131a2de0e1d
https://doi.org/10.1038/s41366-022-01214-z
https://doi.org/10.1038/s41366-022-01214-z
Adolescent female rats recovered from the activity‐based anorexia display blunted hedonic responding
Autor:
Matthew M. Hurley, Ashraf N. Nawari, Victoria X. Chen, Shannon C. O'Brien, Aliasgher I. Sabir, Ethan J. Goodman, Lucas J. Wiles, Aditi Biswas, Sean Andrew Aston, Seva G. Khambadkone, Kellie L. Tamashiro, Timothy H. Moran
Publikováno v:
International Journal of Eating Disorders. 55:1042-1053
As patients with anorexia nervosa tend to "like" palatable tastants less than controls, we set out to model this preclinically by using the taste reactivity test (TRT) to assess hedonic state in rats following weight restoration from a bout of activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434c5bf0d2945484ce280f9de622ce72
https://doi.org/10.1002/eat.23752
https://doi.org/10.1002/eat.23752
Autor:
Gregory Simandl, Gregory J. Simandl, Evan Hess, Linghai Kong, Nicholas J. Raddatz, Matthew M. Hurley, Brian Maunze, SuJean Choi, Aaron M. Geurts, David A. Baker
Publikováno v:
Journal of Clinical and Translational Science. 7:145-145
OBJECTIVES/GOALS: We aim to discover safer and more effective therapeutics for CNS disorders. Current therapeutic development is hindered by dosing out drugs for safe consumption. By identifying proteins with narrow functional roles in the brain (i.e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5345a89067f35d4cc01d7ae26e41af42
https://doi.org/10.1017/cts.2023.510
https://doi.org/10.1017/cts.2023.510
Autor:
Matthew M. Hurley, Brian Maunze, Megan E. Block, Mogen M. Frenkel, Michael J. Reilly, Eugene Kim, Yao Chen, Yan Li, David A. Baker, Qing-Song Liu, SuJean Choi
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
While pituitary adenylate cyclase activating polypeptide (PACAP) signaling in the hypothalamic ventromedial nuclei (VMN) has been shown to regulate feeding, a challenge in unmasking a role for this peptide in obesity is that excess feeding can involv
Externí odkaz:
https://doaj.org/article/bde0f4e8be1b45eebeb927f47525f53a
Autor:
SuJean Choi, Matthew M. Hurley, Megan E. Block, Tanya Dabra, Neerali Patel, Matthew Hearing, Riley McCoy, Michael J. Reilly, William Conley, Eden M. Anderson, Christopher Chen, Brian Maunze, Zane Cooper, Evan Hess
Publikováno v:
Neuroendocrinology
Leptin signaling pathways, stemming primarily from the hypothalamus, are necessary for maintaining normal energy homeostasis and body weight. In both rodents and humans, dysregulation of leptin signaling leads to morbid obesity and diabetes. Since le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a0b94632a6d9c31690ee11b8a6c545
https://doi.org/10.1159/000501337
https://doi.org/10.1159/000501337