Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Matthew M Grabowski"'
Autor:
Lisa H Butterfield, Howard L Kaufman, Steven A Rosenberg, Simon Turcotte, Robert L Ferris, Craig L Slingluff, David Byrd, Jyothi Sethuraman, Brian Gastman, Michael Lim, Michael T Lotze, Mokenge Malafa, Adekunle Odunsi, Fumito Ito, Genevieve Boland, Pranav Murthy, Adam Berger, Haider Mahdi, Piyush K Agarwal, Stephen Broderick, Peter E Fecci, Yuman Fong, Stephanie L Goff, Matthew M Grabowski, Carol D Morris, Rogerio I Neves, Sara I Pai, Sangeetha Prabhakaran, Ragheed Saoud, Joseph Skitzki, Vernon K Sondak, John B Sunwoo, Cecilia CS Yeung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Immunotherapy is now a cornerstone for cancer treatment, and much attention has been placed on the identification of prognostic and predictive biomarkers. The success of biomarker development is dependent on accurate and timely collection of biospeci
Externí odkaz:
https://doaj.org/article/20db5803d1fa467cab907b6e8216be86
Autor:
Tyler J. Alban, Matthew M. Grabowski, Balint Otvos, Defne Bayik, Wesley Wang, Ajay Zalavadia, Vlad Makarov, Katie Troike, Mary McGraw, Anja Rabljenovic, Adam Lauko, Chase Neumann, Gustavo Roversi, Kristin A. Waite, Gino Cioffi, Nirav Patil, Thuy T. Tran, Kathleen McCortney, Alicia Steffens, C. Marcela Diaz, J. Mark Brown, Kathleen M. Egan, Craig M. Horbinski, Jill S. Barnholtz-Sloan, Prajwal Rajappa, Michael A. Vogelbaum, Richard Bucala, Timothy A. Chan, Manmeet S. Ahluwalia, Justin D. Lathia
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Intratumoral heterogeneity is a defining hallmark of glioblastoma, driving drug resistance and ultimately recurrence. Many somatic drivers of microenvironmental change have been shown to affect this heterogeneity and, ultimately, the treatment respon
Externí odkaz:
https://doaj.org/article/235cfdd3465841ec8a0ca9c96d6c14cb
Autor:
Ethan S. Srinivasan, Eric W. Sankey, Matthew M. Grabowski, Pakawat Chongsathidkiet, Peter E. Fecci
Publikováno v:
International Journal of Hyperthermia, Vol 37, Iss 2, Pp 27-34 (2020)
The rise of immunotherapy (IT) in oncological treatment has greatly improved outcomes in a number of disease states. However, its use in tumors of the central nervous system (CNS) remains limited for multiple reasons related to the unique immunologic
Externí odkaz:
https://doaj.org/article/9fab6bc6d79542359923e8cdf938c5d9
Autor:
Eric W. Sankey, Vadim Tsvankin, Matthew M. Grabowski, Gautam Nayar, Kristen A. Batich, Aida Risman, Cosette D. Champion, April K. S. Salama, C. Rory Goodwin, Peter E. Fecci
Publikováno v:
Cancer Medicine, Vol 8, Iss 16, Pp 6809-6831 (2019)
Abstract The number of patients who develop metastatic brain lesions is increasing as the diagnosis and treatment of systemic cancers continues to improve, resulting in longer patient survival. The role of surgery in the management of brain metastasi
Externí odkaz:
https://doaj.org/article/95ca8b3e47a44c8d8b9ee78642166a2e
Autor:
Justin D. Lathia, Feixiong Cheng, Manmeet S. Ahluwalia, Tae Hyun Hwang, Ahmad M. Khalil, Bjarne Winther Kristensen, Craig Horbinski, Michael A. Vogelbaum, Balint Otvos, Matthew M. Grabowski, Mia Sorensen, Mary McGraw, Tyler J. Alban, Alice Lo, Dionysios C. Watson, Gustavo Roversi, Adam Lauko, Daniel J. Silver, Daniel Vail, Changjin Hong, Chihyun Park, Yadi Zhou, Defne Bayik
Supplementary Figures 1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fc2be5baaa02c29a761e36a940bdd0
https://doi.org/10.1158/2159-8290.22535263
https://doi.org/10.1158/2159-8290.22535263
Autor:
Justin D. Lathia, Feixiong Cheng, Manmeet S. Ahluwalia, Tae Hyun Hwang, Ahmad M. Khalil, Bjarne Winther Kristensen, Craig Horbinski, Michael A. Vogelbaum, Balint Otvos, Matthew M. Grabowski, Mia Sorensen, Mary McGraw, Tyler J. Alban, Alice Lo, Dionysios C. Watson, Gustavo Roversi, Adam Lauko, Daniel J. Silver, Daniel Vail, Changjin Hong, Chihyun Park, Yadi Zhou, Defne Bayik
Gene list for network medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f8cc337b4422599431580de88f85dd
https://doi.org/10.1158/2159-8290.22535260.v1
https://doi.org/10.1158/2159-8290.22535260.v1
Data from Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner
Autor:
Justin D. Lathia, Feixiong Cheng, Manmeet S. Ahluwalia, Tae Hyun Hwang, Ahmad M. Khalil, Bjarne Winther Kristensen, Craig Horbinski, Michael A. Vogelbaum, Balint Otvos, Matthew M. Grabowski, Mia Sorensen, Mary McGraw, Tyler J. Alban, Alice Lo, Dionysios C. Watson, Gustavo Roversi, Adam Lauko, Daniel J. Silver, Daniel Vail, Changjin Hong, Chihyun Park, Yadi Zhou, Defne Bayik
Myeloid-derived suppressor cells (MDSC) that block antitumor immunity are elevated in glioblastoma (GBM) patient blood and tumors. However, the distinct contributions of monocytic (mMDSC) versus granulocytic (gMDSC) subsets have yet to be determined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e0a630646e5b7b2422e3f94b7612de
https://doi.org/10.1158/2159-8290.c.6547804.v1
https://doi.org/10.1158/2159-8290.c.6547804.v1
Autor:
Justin D. Lathia, Peter E. Fecci, Michael A. Vogelbaum, Manmeet S. Ahluwalia, Gene H. Barnett, Alireza M. Mohammadi, Charlie Androjna, Sarah Johnson, Anja Rabljenovic, Tomas Radivoyevitch, Erin E. Mulkearns-Hubert, Defne Bayik, Matthew M. Grabowski, Tyler J. Alban, Balint Otvos
Supplementary Figures 1-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79db2696cb399dbd733477034c5e2e5b
https://doi.org/10.1158/1078-0432.22480611
https://doi.org/10.1158/1078-0432.22480611
Autor:
Justin D. Lathia, Peter E. Fecci, Michael A. Vogelbaum, Manmeet S. Ahluwalia, Gene H. Barnett, Alireza M. Mohammadi, Charlie Androjna, Sarah Johnson, Anja Rabljenovic, Tomas Radivoyevitch, Erin E. Mulkearns-Hubert, Defne Bayik, Matthew M. Grabowski, Tyler J. Alban, Balint Otvos
Purpose:Glioblastoma (GBM) immunotherapy clinical trials are generally initiated after standard-of-care treatment—including surgical resection, perioperative high-dose steroid therapy, chemotherapy, and radiation treatment—has either begun or fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c754b628c0a8f6914a50a0502301a1
https://doi.org/10.1158/1078-0432.c.6530484.v1
https://doi.org/10.1158/1078-0432.c.6530484.v1
Autor:
Matthew M. Grabowski, Dionysios C. Watson, Kunho Chung, Juyeun Lee, Defne Bayik, Adam Lauko, Tyler Alban, Jan Joseph Melenhorst, Timothy Chan, Justin D. Lathia, Manmeet S. Ahluwalia, Alireza M. Mohammadi
SummaryGlioblastoma (GBM) treatment includes maximal safe resection of the core and MRI contrast-enhancing (CE) tumor. Complete resection of the infiltrative non-contrast-enhancing (NCE) tumor rim is rarely achieved. We established a safe, semi-autom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9fc2656de8d9fa4d2710dc66f70cc05
https://doi.org/10.1101/2023.03.09.23285970
https://doi.org/10.1101/2023.03.09.23285970