Unveiling the epigenetic impact of vegan vs. omnivorous diets on aging: insights from the Twins Nutrition Study (TwiNS)

Autor: Varun B. Dwaraka, Lucia Aronica, Natalia Carreras-Gallo, Jennifer L. Robinson, Tayler Hennings, Matthew M. Carter, Michael J. Corley, Aaron Lin, Logan Turner, Ryan Smith, Tavis L. Mendez, Hannah Went, Emily R. Ebel, Erica D. Sonnenburg, Justin L. Sonnenburg, Christopher D. Gardner

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-19 (2024)

Abstract Background Geroscience focuses on interventions to mitigate molecular changes associated with aging. Lifestyle modifications, medications, and social factors influence the aging process, yet the complex molecular mechanisms require an in-dep

Externí odkaz: https://doaj.org/article/869a3e24e5c04b8ab44dadf995536283

A microbiome‐targeting fibre‐enriched nutritional formula is well tolerated and improves quality of life and haemoglobin A1c in type 2 diabetes: A double‐blind , randomized, placebo‐controlled trial

Autor: Juan P. Frias, Martin L. Lee, Matthew M. Carter, Emily R. Ebel, Ren‐Hau Lai, Lars Rikse, Marc E. Washington, Justin L. Sonnenburg, Christopher J. Damman

Publikováno v: Diabetes, Obesity and Metabolism. 25:1203-1212

To investigate a prebiotic fiber-enriched nutritional formula on health-related quality of life and metabolic control in type 2 diabetes.This was a 12-week, double-blind, placebo-controlled study with an unblinded dietary advice only comparator arm.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b2412dd6e0f905a8dfead0d92b8858
https://doi.org/10.1111/dom.14967

Butyrate Differentiates Permissiveness to Clostridioides difficile Infection and Influences Growth of Diverse C. difficile Isolates

Autor: Daniel A. Pensinger, Andrea T. Fisher, Horia A. Dobrila, William Van Treuren, Jackson O. Gardner, Steven K. Higginbottom, Matthew M. Carter, Benjamin Schumann, Carolyn R. Bertozzi, Victoria Anikst, Cody Martin, Elizabeth V. Robilotti, Jo May Chow, Rachael H. Buck, Lucy S. Tompkins, Justin L. Sonnenburg, Andrew J. Hryckowian

Publikováno v: Infection and Immunity. 91

A disrupted “dysbiotic” gut microbiome engenders susceptibility to the diarrheal pathogen Clostridioides difficile by impacting the metabolic milieu of the gut. Diet, in particular the microbiota accessible carbohydrates (MACs) found in dietary f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015982d9e1c831b25f4989643d7cb525
https://doi.org/10.1128/iai.00570-22

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

Autor: Robert C, Jones, Jim, Karkanias, Mark A, Krasnow, Angela Oliveira, Pisco, Stephen R, Quake, Julia, Salzman, Nir, Yosef, Bryan, Bulthaup, Phillip, Brown, William, Harper, Marisa, Hemenez, Ravikumar, Ponnusamy, Ahmad, Salehi, Bhavani A, Sanagavarapu, Eileen, Spallino, Ksenia A, Aaron, Waldo, Concepcion, James M, Gardner, Burnett, Kelly, Nikole, Neidlinger, Zifa, Wang, Sheela, Crasta, Saroja, Kolluru, Maurizio, Morri, Serena Y, Tan, Kyle J, Travaglini, Chenling, Xu, Marcela, Alcántara-Hernández, Nicole, Almanzar, Jane, Antony, Benjamin, Beyersdorf, Deviana, Burhan, Kruti, Calcuttawala, Matthew M, Carter, Charles K F, Chan, Charles A, Chang, Stephen, Chang, Alex, Colville, Rebecca N, Culver, Ivana, Cvijović, Gaetano, D'Amato, Camille, Ezran, Francisco X, Galdos, Astrid, Gillich, William R, Goodyer, Yan, Hang, Alyssa, Hayashi, Sahar, Houshdaran, Xianxi, Huang, Juan C, Irwin, SoRi, Jang, Julia Vallve, Juanico, Aaron M, Kershner, Soochi, Kim, Bernhard, Kiss, William, Kong, Maya E, Kumar, Angera H, Kuo, Rebecca, Leylek, Baoxiang, Li, Gabriel B, Loeb, Wan-Jin, Lu, Sruthi, Mantri, Maxim, Markovic, Patrick L, McAlpine, Antoine, de Morree, Karim, Mrouj, Shravani, Mukherjee, Tyler, Muser, Patrick, Neuhöfer, Thi D, Nguyen, Kimberly, Perez, Ragini, Phansalkar, Nazan, Puluca, Zhen, Qi, Poorvi, Rao, Hayley, Raquer-McKay, Nicholas, Schaum, Bronwyn, Scott, Bobak, Seddighzadeh, Joe, Segal, Sushmita, Sen, Shaheen, Sikandar, Sean P, Spencer, Lea C, Steffes, Varun R, Subramaniam, Aditi, Swarup, Michael, Swift, Will, Van Treuren, Emily, Trimm, Stefan, Veizades, Sivakamasundari, Vijayakumar, Kim Chi, Vo, Sevahn K, Vorperian, Wanxin, Wang, Hannah N W, Weinstein, Juliane, Winkler, Timothy T H, Wu, Jamie, Xie, Andrea R, Yung, Yue, Zhang, Angela M, Detweiler, Honey, Mekonen, Norma F, Neff, Rene V, Sit, Michelle, Tan, Jia, Yan, Gregory R, Bean, Vivek, Charu, Erna, Forgó, Brock A, Martin, Michael G, Ozawa, Oscar, Silva, Angus, Toland, Venkata N P, Vemuri, Shaked, Afik, Kyle, Awayan, Olga Borisovna, Botvinnik, Ashley, Byrne, Michelle, Chen, Roozbeh, Dehghannasiri, Adam, Gayoso, Alejandro A, Granados, Qiqing, Li, Gita, Mahmoudabadi, Aaron, McGeever, Julia Eve, Olivieri, Madeline, Park, Neha, Ravikumar, Geoff, Stanley, Weilun, Tan, Alexander J, Tarashansky, Rohan, Vanheusden, Peter, Wang, Sheng, Wang, Galen, Xing, Rebecca, Culver, Les, Dethlefsen, Po-Yi, Ho, Shixuan, Liu, Jonathan S, Maltzman, Ross J, Metzger, Koki, Sasagawa, Rahul, Sinha, Hanbing, Song, Bruce, Wang, Steven E, Artandi, Philip A, Beachy, Michael F, Clarke, Linda C, Giudice, Franklin W, Huang, Kerwyn Casey, Huang, Juliana, Idoyaga, Seung K, Kim, Mark, Krasnow, Christin S, Kuo, Patricia, Nguyen, Thomas A, Rando, Kristy, Red-Horse, Jeremy, Reiter, David A, Relman, Justin L, Sonnenburg, Albert, Wu, Sean M, Wu, Tony, Wyss-Coray

Publikováno v: Science
Tabula Sapiens Consortium* 2022, ' The Tabula Sapiens : A multiple-organ, single-cell transcriptomic atlas of humans ', Science (New York, N.Y.), vol. 376, no. 6594, pp. eabl4896 . https://doi.org/10.1126/science.abl4896

INTRODUCTION: Although the genome is often called the blueprint of an organism, it is perhaps more accurate to describe it as a parts list composed of the various genes that may or may not be used in the different cell types of a multicellular organi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f726fc016f86cd4ce8c15a69dce9f6be
https://pubmed.ncbi.nlm.nih.gov/36198687

Microbiome assembly in The Gambia

Autor: Matthew M. Carter, Matthew R. Olm, Erica D. Sonnenburg

Publikováno v: Nature Microbiology. 7:18-19

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d405af779eb1850d587f7f283a872cd
https://doi.org/10.1038/s41564-021-01036-1