Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Matthew Loberg"'
Publikováno v:
Journal of the American Society of Cytopathology. 11:S64
Publikováno v:
Experimental Hematology. 111:S136-S137
Autor:
Tim Stearns, Simon Haas, Jennifer J. Trowbridge, Matthew Loberg, Lars Velten, Elizabeth Eudy, Rebecca Bell, Kira Young
Hematopoietic stem cells (HSCs) are responsible for lifelong maintenance and regeneration of the blood system. With aging, loss of HSC function is a major contributor to decline in overall hematopoietic function, leading to increased rate of infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42d36ddf6200e2d087b0ef075475b666
https://doi.org/10.1101/2020.07.11.198846
https://doi.org/10.1101/2020.07.11.198846
Autor:
Jennifer J. Trowbridge, Elizabeth Eudy, Kristina D. Mujica, Logan S. Schwartz, Kira Young, Matthew Loberg
The MLL-AF9 fusion protein occurring as a result of t(9;11) translocation gives rise to pediatric and adult acute leukemias of distinct lineages, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and mixed phenotype acute le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76dc4c731988660c0e63c9609f9110d6
https://doi.org/10.1101/2020.06.13.149310
https://doi.org/10.1101/2020.06.13.149310
Autor:
Jennifer J. Trowbridge, Kristina D. Mujica, Logan S. Schwartz, Matthew Loberg, Kira Young, Elizabeth Eudy
Publikováno v:
Exp Hematol
The MLL-AF9 fusion protein occurring as a result of t(9;11) translocation gives rise to pediatric and adult acute leukemias of distinct lineages, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and mixed-phenotype acute le
Autor:
Matthew Loberg, Marie-Dominique Filippi, Kira Young, Lars Velten, Tim Stearns, Elizabeth Eudy, Simon Haas, Rebecca Bell, Jennifer J. Trowbridge, Devyani Sharma
Publikováno v:
Cell Stem Cell
Decline in hematopoietic stem cell (HSC) function with age underlies limited health span of our blood and immune systems. In order to preserve health into older age, it is necessary to understand the nature and timing of initiating events that cause
Autor:
Kristin M Allan, Wesley J. Murphy, Jennifer E. Hurtig, Juliet Chepngeno, Jonathan K. Allotey, Herbert Sizek, Kevin A. Morano, Matthew Loberg, Jennifer M. Pilat, Afton H. Widdershins, Susmit Tripathi, Matthew R. Naticchia, Min Goo Kang, Joseph B. David, James West
Publikováno v:
Free Radical Biology and Medicine. 101:356-366
A broad range of redox-regulated proteins undergo reversible disulfide bond formation on oxidation-prone cysteine residues. Heightened reactivity of the thiol groups in these cysteines also increases susceptibility to modification by organic electrop
Autor:
Joseph E Kelly, Matthew Spencer, John A Buchan, Jill E. Clodfelter, James West, Aaron H. Graff, Matthew Loberg, Kevin A. Morano, Jennifer E. Hurtig, W. Todd Lowther, Kristin M Allan
Publikováno v:
Chemical research in toxicology. 32(3)
To prevent the accumulation of reactive oxygen species and limit associated damage to biological macromolecules, cells express a variety of oxidant-detoxifying enzymes, including peroxiredoxins. In Saccharomyces cerevisiae, the peroxiredoxin Tsa1 pla
Publikováno v:
Blood. 134:526-526
Hematopoietic stem cells (HSCs) are responsible for long-term maintenance and regeneration of the hematopoietic system. Loss of long-term (LT)-HSC function is a major contributor to decline in hematopoietic function with aging, leading to increased r
Autor:
Kira Young, Matthew Loberg, Jennifer M. SanMiguel, Jennifer J. Trowbridge, Sarah Heuer, Tim Stearns
Publikováno v:
Blood. 134:5-5
During aging, intrinsic and extrinsic stressors are thought to contribute to clonal expansion of HSCs carrying somatic mutations, leading to clonal hematopoiesis (CH). While CH is benign in the majority of individuals, the presence of CH is associate