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pro vyhledávání: '"Matthew Lalonde"'
Autor:
Erika A. Eksioglu, Gabriela M. Wright, Jason M. Foulks, Matthew Lalonde, Steven L. Warner, Kenneth L. Wright
Publikováno v:
Cancer Research. 83:5150-5150
Background: The inflammaging modulator, S100A9, mediates immunosuppression and plays a key role in the pathogenesis of low-risk myelodysplastic syndrome (MDS). Specifically, S100A9’s feedforward activation in the bone marrow (BM) induces pyroptotic
Autor:
Yuta Matsumura, Ethika Tyagi, Steven L. Warner, Satya Pathi, Adam Siddiqui, Curtis A. Allred, Salah Sommakia, Matthew Lalonde, David J. Bearss, Clifford J. Whatcott, Jason M. Foulks
Publikováno v:
Cancer Research. 81:606-606
Pyruvate kinase is a crucial enzyme responsible for the last step of glycolysis. Cancer cells can use the M2 isoform of pyruvate kinase (PKM2), to better balance respiration and biosynthesis due to allosteric switching between the less active dimeric
Autor:
Clifford J. Whatcott, David J. Bearss, Steve Warner, Jason M. Foulks, Joshua L. Andersen, Ethika Tyagi, Tetyana V. Forostyan, Adam Siddiqui, Matthew Lalonde
Publikováno v:
Cancer Research. 81:1478-1478
TNK1 (thirty-eight-negative kinase 1) is an ACK non-receptor tyrosine kinase expressed during developmental hematopoiesis. Expression in adult tissues has been implicated in hematologic malignancies and in mediation of cellular stress and apoptosis.