Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Matthew L. Stein"'
Autor:
Ronan C. Bracken, Lindsay M. Davison, Dennis P. Buehler, Maci E. Fulton, Emily E. Carson, Quanhu Sheng, Lindsey K. Stolze, Christelle Guillermier, Matthew L. Steinhauser, Jonathan D. Brown
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110011- (2024)
Summary: Combinatorial signaling by proinflammatory cytokines synergizes to exacerbate toxicity to cells and tissue injury during acute infections. To explore synergism at the gene-regulatory level, we investigated the dynamics of transcription and c
Externí odkaz:
https://doaj.org/article/968e40391d4f4f4f936e241935d0f84b
Autor:
Niyatie Ammanamanchi, Jessie Yester, Anita P. Bargaje, Dawn Thomas, Kathryn C. Little, Shannon Janzef, Kimberly Francis, Jacqueline Weinberg, Jennifer Johnson, Thomas Seery, Tyler Hutchinson Harris, Bryan J. Funari, Kirsten Rose-Felker, Matthew Zinn, Susan A. Miller, Shawn C. West, Brian Feingold, Hairu Zhou, Matthew L. Steinhauser, Timothy Csernica, Robert Michener, Bernhard Kühn
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/b14b4c429d99421f8e7ed27a267d1878
Autor:
Mei Massengale, Justin L. Massengale, Catherine R. Benson, Ninib Barywano, Toshihiko Oki, Matthew L. Steinhauser, Alissa Wang, Deepak Balani, Luke S. Oh, Mark A. Randolph, Thomas J. Gill III, Henry M. Kronenberg, David T. Scadden
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
The identity and origin of the stem/progenitor cells for adult joint cartilage repair remain unknown, impeding therapeutic development. Simulating the common therapeutic modality for cartilage repair in humans, i.e., full-thickness microfracture join
Externí odkaz:
https://doaj.org/article/93dd27813cb9489d8c95bbc3880422ed
Autor:
Jeffrey R. Erickson, C. Blake Nichols, Matthew L. Stein, Hitoshi Uchinoumi, Julie Bossuyt, Donald M. Bers
Publikováno v:
The Journal of biological chemistry, vol 290, iss 42
Erickson, JR; Nichols, CB; Uchinoumi, H; Stein, ML; Bossuyt, J; & Bers, DM. (2015). S-nitrosylation induces both autonomous activation and inhibition of calcium/calmodulin-dependent protein Kinase II δ. Journal of Biological Chemistry, 290(42), 25646-25656. doi: 10.1074/jbc.M115.650234. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6d41p06j
Erickson, JR; Nichols, CB; Uchinoumi, H; Stein, ML; Bossuyt, J; & Bers, DM. (2015). S-nitrosylation induces both autonomous activation and inhibition of calcium/calmodulin-dependent protein Kinase II δ. Journal of Biological Chemistry, 290(42), 25646-25656. doi: 10.1074/jbc.M115.650234. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6d41p06j
© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. NO is known to modulate calcium handling and cellular signaling in the myocardium, but key targets for NO in the heart remain unidentified. Recent reports have implied that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3936ad3d9fc92d91c1684eda7498836
https://escholarship.org/uc/item/6d41p06j
https://escholarship.org/uc/item/6d41p06j
Publikováno v:
Biophysical Journal. 112:532a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30b4b99b7162fae806c17b3520b5ab6c
https://doi.org/10.1016/j.bpj.2016.11.2875
https://doi.org/10.1016/j.bpj.2016.11.2875
Autor:
Bradley M. Wertheim, Rui-Sheng Wang, Christelle Guillermier, Christiane V.R. Hütter, William M. Oldham, Jörg Menche, Matthew L. Steinhauser, Bradley A. Maron
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
In pulmonary arterial hypertension (PAH), inflammation promotes a fibroproliferative pulmonary vasculopathy. Reductionist studies emphasizing single biochemical reactions suggest a shift toward glycolytic metabolism in PAH; however, key questions rem
Externí odkaz:
https://doaj.org/article/3241f24b97504570a5420e07c730d523
Autor:
Amanda Ferguson, Julie Bossuyt, Chia Wei Chang, Maura Ferrero, Derrick Ha, Matthew L. Stein, Sven Bossuyt, Robert R. Rigor, C. Blake Nichols, Brent M. Wood
Rationale: Both β-adrenergic receptor (β-AR) and G q -coupled receptor (G q R) agonist–driven signaling play key roles in the events, leading up to and during cardiac dysfunction. How these stimuli interact at the level of protein kinase D (PKD),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0157de0c254c373ca75e4efd0045871
https://europepmc.org/articles/PMC4031034/
https://europepmc.org/articles/PMC4031034/
Autor:
Pouneh K. Fazeli, Yang Zhang, John O'Keefe, Tristan Pesaresi, Mingyue Lun, Brian Lawney, Matthew L. Steinhauser
Publikováno v:
Molecular Metabolism, Vol 42, Iss , Pp 101082- (2020)
Objective: The human adaptive fasting response enables survival during periods of caloric deprivation. A crucial component of the fasting response is the shift from glucose metabolism to utilization of lipids, underscoring the importance of adipose t
Externí odkaz:
https://doaj.org/article/eea256eefcbb4ae38c4dc685cec26e37
Autor:
Yang Zhang, Christelle Guillermier, Thomas De Raedt, Andrew G. Cox, Ophelia Maertens, Dean Yimlamai, Mingyue Lun, Adam Whitney, Richard L. Maas, Wolfram Goessling, Karen Cichowski, Matthew L. Steinhauser
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101355- (2020)
Summary: Malignant tumors exhibit high degrees of genomic heterogeneity at the cellular level, leading to the view that subpopulations of tumor cells drive growth and treatment resistance. To examine the degree to which tumors also exhibit metabolic
Externí odkaz:
https://doaj.org/article/65c606e11867455bb254d8409165dc47
Autor:
Ana Vujic, Carolin Lerchenmüller, Ting-Di Wu, Christelle Guillermier, Charles P. Rabolli, Emilia Gonzalez, Samuel E. Senyo, Xiaojun Liu, Jean-Luc Guerquin-Kern, Matthew L. Steinhauser, Richard T. Lee, Anthony Rosenzweig
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The adult mammalian heart has a limited cardiomyogenic capacity. Here the authors show that intensive exercise leads to a 4.6-fold increase in murine cardiomyocyte proliferation requiring the expression of miR-222, and that exercise induces an extend
Externí odkaz:
https://doaj.org/article/2df138bce0e446388382bb5c88daeae8